Destination memory in Alzheimer’s Disease: When I imagine telling Ronald Reagan about Paris

Haj, Mohamad El; Postal, Virginie; Allain, Philippe

doi:10.1016/j.cortex.2011.11.014

Cited by 56 publications

(54 citation statements)

References 23 publications

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“…Our results extend those of previous studies [1,3] as they show a decline in destination memory in normal aging and even greater decline in AD subjects. The decline in the latter could be due to inhibitory dysfunction.…”

Section: Discussionsupporting

confidence: 91%

“…This hypothesis is in line with the theory of Lustig and colleagues [5] who attribute the memory decline observed with normal aging to inhibitory deterioration. Recent reports also relate the memory decline in AD patients to inhibitory dysfunction [3,6].…”

Section: Discussionmentioning

confidence: 99%

“…This procedure has been fully described elsewhere [3,4]. Table 1 shows the performance on the executive and destination tasks.…”

Section: Methodsmentioning

confidence: 99%

“…They had to determine whether they had previously told that fact to that face or not. A corrected recognition score for each participant was calculated as the proportion of hits (i.e., correct yes responses) minus the proportion of false alarms (i.e., incorrect yes responses) (for a similar procedures, see, El Haj and colleagues [3]). …”

Section: Methodsmentioning

confidence: 99%

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Destination Memory in Mild Alzheimer’s Disease

Haj

Postal

Gall

et al. 2013

Behavioural Neurology

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Abstract. In order to assess their destination memory, sixteen patients with probable mild Alzheimer Disease (AD), sixteen older adults and 16 young adults were asked to tell facts to pictures. On a subsequent task, they were asked to remember whether they had previously told that fact to that face or not. AD patients showed poorer destination recall than the older adults, and the older adults showed poorer destination recall than the young adults. Our results suggest that destination memory is highly impaired in AD.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

“…This procedure has been fully described elsewhere [3,4]. Table 1 shows the performance on the executive and destination tasks.…”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Destination Memory in Mild Alzheimer’s Disease

Haj

Postal

Gall

et al. 2013

Behavioural Neurology

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“…Up to now, target memory has exclusively been studied in FtF contexts. In a prototypical paradigm participants are placed in fictitious communication situations where they have to tell multiple facts to multiple persons; afterwards their target memory is assessed and, for example, compared to their memory for facts alone (El Haj, Postal, & Allain, 2013;Gopie & MacLeod, 2009;Gopie, Craik, & Hasher, 2010). Results show that people generally remember their communication partners and conversation topics quite well separately, but struggle with target memory (Brown, Hornstein, & Memon, 2006;Gopie & MacLeod, 2009;Gopie et al, 2010;Marsh & Hicks, 2002).…”

Section: Target Memorymentioning

confidence: 97%

For they know not what they do? Target memory and metacognitive monitoring of self-disclosures on social networking sites

Pieschl

Moll

2016

Computers in Human Behavior

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Flexibility decline contributes to similarity of past and future thinking in Alzheimer's disease

2015

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A striking similarity has been suggested between past and future thinking in Alzheimer’s Disease (AD), a similarity attributable to abnormalities in common modular cognitive functions and neuroanatomical substrates. This study extends this literature by identifying specific executive function deficits underlying past and future thinking in AD. Twenty-four participants with a clinical diagnosis of probable (mild) AD and 26 older controls generated past and future events and underwent tests of binding and the executive functions of flexibility, inhibition, and updating. AD patients showed similar autobiographical performances in past and future event generation, and so did control participants. In each group, the similarity of past and future thinking was predicted by flexibility. Furthermore, AD patients with low flexibility showed higher similarity of past and future thinking than those with high flexibility. These findings are interpreted in terms of involvement of the hippocampus and frontal lobes in future thinking. Deficits in these brain regions in AD are likely to compromise the ability to recombine episodic information into novel and flexible configurations as scenarios for the future.

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Destination memory in Alzheimer’s Disease: When I imagine telling Ronald Reagan about Paris

Cited by 56 publications

References 23 publications

Destination Memory in Mild Alzheimer’s Disease

Destination Memory in Mild Alzheimer’s Disease

For they know not what they do? Target memory and metacognitive monitoring of self-disclosures on social networking sites

Flexibility decline contributes to similarity of past and future thinking in Alzheimer's disease

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