Design optimization of biomedical stent under the influence of the radial pressure using FEM

Britto, J. Jerold John; Venkatesh, Ramakrishna; Prabhakaran, R.; Amudhan, K.

doi:10.1016/j.matpr.2020.04.567

Cited by 5 publications

(2 citation statements)

References 14 publications

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“…The optimization of biodegradable stents for cardiovascular applications has been carried out by several authors with the aim of evaluating the impact of geometrical features on mechanical performance [ 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 ] or trying to provide optimal designs pursuing specific hemodynamic, structural and geometrical objectives [ 50 , 51 , 52 ]. Unfortunately, these thresholds are not clearly defined for a tracheobronchial device: the main problem is migration, so radial force should be the criterion for optimization.…”

Section: Introductionmentioning

confidence: 99%

Computational Analysis of Polymeric Biodegradable and Customizable Airway Stent Designs

Ayechu-Abendaño,

Pérez-Jiménez,

Sánchez-Matás

et al. 2024

Polymers

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The placement of endotracheal prostheses is a procedure used to treat tracheal lesions when no other surgical options are available. Unfortunately, this technique remains controversial. Both silicon and metallic stents are used with unpredictable success rates, as they have advantages but also disadvantages. Typical side effects include restenosis due to epithelial hyperplasia, obstruction and granuloma formation. Repeat interventions are often required. Biodegradable stents are promising in the field of cardiovascular biomechanics but are not yet approved for use in the respiratory system. The aim of the present study is to summarize important information and to evaluate the role of different geometrical features for the fabrication of a new tracheo-bronchial prosthesis prototype, which should be biodegradable, adaptable to the patient’s lesion and producible by 3D printing. A parametric design and subsequent computational analysis using the finite element method is carried out. Two different stent designs are parameterized and analyzed. The biodegradable material chosen for simulations is polylactic acid. Experimental tests are conducted for assessing its mechanical properties. The role of the key design parameters on the radial force of the biodegradable prosthesis is investigated. The computational results allow us to elucidate the role of the pitch angle, the wire thickness and the number of cells or units, among other parameters, on the radial force. This work may be useful for the design of ad hoc airway stents according to the patient and type of lesion.

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Section: Introductionmentioning

confidence: 99%

Computational Analysis of Polymeric Biodegradable and Customizable Airway Stent Designs

Ayechu-Abendaño,

Pérez-Jiménez,

Sánchez-Matás

et al. 2024

Polymers

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“…Migliavacca et al [21,22] applied the FEM to understand the effects of different geometric parameters (thickness, metal to arterial surface ratio, longitudinal and radial cut lengths) of a typical diamond-shaped coronary stent on its mechanical performance. Etave et al [23], Pant et al [24], Britto et al [25] and Wei et al [26] proposed several stent designs with different geometry by varying the shape of the circumferential rings and the links and investigated how to improve the design. Liu et al [27,28] demonstrated the feasibility of using shape memory polymers (SMPs) for vascular stent design.…”

Section: Introductionmentioning

confidence: 99%

Computational Analysis of Mechanical Performance for Composite Polymer Biodegradable Stents

et al. 2021

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Bioresorbable stents (BRS) represent the latest generation of vascular scaffolds used for minimally invasive interventions. They aim to overcome the shortcomings of established bare-metal stents (BMS) and drug-eluting stents (DES). Recent advances in the field of bioprinting offer the possibility of combining biodegradable polymers to produce a composite BRS. Evaluation of the mechanical performance of the novel composite BRS is the focus of this study, based on the idea that they are a promising solution to improve the strength and flexibility performance of single material BRS. Finite element analysis of stent crimping and expansion was performed. Polylactic acid (PLA) and polycaprolactone (PCL) formed a composite stent divided into four layers, resulting in sixteen unique combinations. A comparison of the mechanical performance of the different composite configurations was performed. The resulting stresses, strains, elastic recoil, and foreshortening were evaluated and compared to existing experimental results. Similar behaviour was observed for material configurations that included at least one PLA layer. A pure PCL stent showed significant elastic recoil and less shortening compared to PLA and composite structures. The volumetric ratio of the materials was found to have a more significant effect on recoil and foreshortening than the arrangement of the material layers. Composite BRS offer the possibility of customising the mechanical behaviour of scaffolds. They also have the potential to support the fabrication of personalised or plaque-specific stents.

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In Silico Evaluation of Bilinear Elastoplastic Coronary Artery Stents

Alihemmati

Vahidi

Nik³

et al. 2021

Adv Eng Mater

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Design optimization of biomedical stent under the influence of the radial pressure using FEM

Cited by 5 publications

References 14 publications

Computational Analysis of Polymeric Biodegradable and Customizable Airway Stent Designs

Computational Analysis of Polymeric Biodegradable and Customizable Airway Stent Designs

Computational Analysis of Mechanical Performance for Composite Polymer Biodegradable Stents

In Silico Evaluation of Bilinear Elastoplastic Coronary Artery Stents

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