Design of a randomized controlled trial to assess the comparative effectiveness of a multifaceted intervention to improve three-year adherence to colorectal cancer screening among patients cared for in rural community health centers

Davis, Terry C.; Morris, James; Reed, Elise H; Curtis, Laura M.; Wolf, Michael S.; Davis, Adrienne B.; Arnold, Connie L.

doi:10.1016/j.cct.2021.106654

Cited by 2 publications

(1 citation statement)

References 28 publications

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“…One study ranked at level I, eleven studies ranked at level II, followed by seven at level III, and one at level V. The most common limitation was decreased generalizability due to sampling homogeneity and insufficiency as found in 11 studies [4,14,[17][18][19][20][21][22][23][24][25]. The other limitations were unaccounted confounders, overreporting, nonexperimental designs, data heterogeneity, and high attrition rates respectively [4,[24][25][26][27][28]. The strength in many of the studies was the randomization of participants as seen in the samples of ten studies.…”

Section: Quality Assessmentmentioning

confidence: 99%

Are Contemporary Interventions Effectively Lowering Barriers to Colorectal Cancer Screening in African Americans?

2023

J Community Med Public Health

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Background: African Americans (AAs) disproportionately experience higher prevalence and mortality rates of colorectal cancer (CRC) compared to other racial groups in the United States [1]. Despite advancements in screening methods, CRC screening rates in AA adults have remained marginally lower than projected quotas aimed at slowing prevalence and mortality rates [2]. Notably, AA populations face multi-causal barriers to CRC screening adherence. Barriers can be categorized into socioeconomic disparities, decreased proximity and access to healthcare providers, knowledge and self-efficacy disparity, and ongoing systemic and social bias [3][4][5]. Researchers, public health stakeholders, and healthcare professionals are currently exploring various interventions to curb demographic barriers and increase AA CRC screening rates. Method: This systematic review synthesized evidence from 20 recent studies on the interventions implemented to increase CRC screening rates in AA adults 45 years and older. Searching peer-reviewed, freely accessible articles written in English and published from 2019 to 2023 yielded over 400 citations with keywords below. These citations were narrowed down further to 163 by hand searching and eliminating studies that did not address colorectal cancer screenings. These studies were exported to a reference management application called RefWorks, which was used to eliminate any duplicate studies. After eliminating duplicate studies, the resulting 142 studies' abstracts were hand searched and separated into folders based on studies that discussed CRC screening rates in AA, CRC screening rates in the general population, and CRC screening interventions. These three folders of studies were then reviewed. Studies that were not experimental or quasi-experimental, not based in the United States, and did not include AA participants were all filtered out and excluded. This process left 40 articles for manual review based on inclusion and exclusion criteria, as seen in Figure 1. This review process yielded 20 final articles for analysis in the systematic review. Results: The literature review indicates that the most effective interventions that increase screening intent and completion in AA adults are multi-modal, patient-centered, and accessibility. Further, direct-to-patient delivered Fecal Immunochemical Test (FIT) kits showed a statistically significant increase in screening adherence compared to traditional endoscopic methods. This review illuminated the need for further research with larger sample sizes, better generalizability, multiregional AA populations, and increased AA male participants. Conclusion & Implications: This review has been instrumental in highlighting the importance of convenient, at-home, non-invasive, and low-cost testing options in filling this screening gap. One of the hypotheses of this review that may have otherwise been falsely accepted was proven wrong because a systematic review enabled the investigator to conduct a comprehensive, multifaceted exploration of the topic. This ...

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Section: Quality Assessmentmentioning

confidence: 99%

Are Contemporary Interventions Effectively Lowering Barriers to Colorectal Cancer Screening in African Americans?

2023

J Community Med Public Health

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Chemotherapy delivery in early-onset colorectal cancer is impacted by urban versus rural settings in Colorado

Sheneman,

Hu,

Das

et al. 2024

Colorectal Cancer

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Design of a randomized controlled trial to assess the comparative effectiveness of a multifaceted intervention to improve three-year adherence to colorectal cancer screening among patients cared for in rural community health centers

Cited by 2 publications

References 28 publications

Are Contemporary Interventions Effectively Lowering Barriers to Colorectal Cancer Screening in African Americans?

Are Contemporary Interventions Effectively Lowering Barriers to Colorectal Cancer Screening in African Americans?

Chemotherapy delivery in early-onset colorectal cancer is impacted by urban versus rural settings in Colorado

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