Abstract:A continuously operated
single-stage mixed suspension–mixed
product removal (MSMPR) crystallizer was developed for the continuous
cooling crystallization of 2-chloro-
N
-(4-methylphenyl)propanamide
(CNMP) in toluene from 25 to 0 °C. The conversion of the previous
batch to a continuous process was key to developing a methodology
linking the synthesis and purification unit operations of CNMP and
gave further insight in the development of continuous process trains
for active pharmaceutical … Show more
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