Design and characterisation of a phased antenna array for intact breast hyperthermia

Curto, Sergio; García-Miquel, Aleix; Suh, Myung‐Won; Vidal, N.; López-Villegas, J.M.; Prakash, Punit

doi:10.1080/02656736.2017.1337935

Cited by 30 publications

(41 citation statements)

References 49 publications

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“…In practical tests, according to some references, 29,30 a fresh ex vivo chicken breast ( ε r = 57.75 [F/M], σ = 1.49 [S/M], C = 2156 [J/(Kg.°C)], K = 0.53 [W/(m.°C)] 27,29,30 ) can be used. Therefore, simulations were repeated considering the experimental setup, i. e. single layer ex vivo chicken breast as phantom.…”

Section: Methodsmentioning

confidence: 99%

“…Recently, wearable hyperthermia applicators have been proposed because of their more convenient structure 29,30 . Besides, wearable structures usually need less power due to their small water bolus volume.…”

Section: Introductionmentioning

confidence: 99%

“…Besides, wearable structures usually need less power due to their small water bolus volume. In Reference 29, a single antenna wearable applicator in order to achieve the tumor temperature of 46°C 30 has been designed. However, this applicator needs a high input power and is less proper for superficial and also deep tumors.…”

Section: Introductionmentioning

confidence: 99%

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Applying a repetitive time‐reversal method to reduce input power of a wearable hyperthermia applicator for breast cancer treatment

Rahimi

Chamaani

2020

Micro & Optical Tech Letters

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In this article, a hyperthermia healing system is presented for cancer treatment. To alleviate most of the microwave hyperthermia systems problems, such as high input power, complicated beamforming method, unwanted hot spots for superficial tumors, and bulky profile, a simple repetitive time‐reversal method is proposed to design a low power wearable hyperthermia applicator with low hotspots at 915 MHz. The objective of this algorithm is to obtin the desired focusing by the minimum possible number of antennas in an appropriate time and minimum required input power. In this paper, first, a symmetric 11‐element patch array is considered. Then, by applying a repetitive time‐reversal method, the number of elements decreases to 7 for deep and 4 for both superficial and intermediate tumors, respectively. The steady‐state temperature/specific absorption rate focusing and transient thermal analysis are investigated in CST MWS and COMSOL, respectively. The target temperature of 43°C is met after less than 10 minutes. The focusing diameter size varies between 1 and 2 cm depending on the number of elements and arrangements considered for different tumors. Compared to literature, this applicator needs very low input power, produces less unwanted hotspots, improves pationt comfort, reduces treatment cost which all leads to patient treatment persistency. Moreover, it does not need any complicated beamforming method.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Applying a repetitive time‐reversal method to reduce input power of a wearable hyperthermia applicator for breast cancer treatment

Rahimi

Chamaani

2020

Micro & Optical Tech Letters

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“…In addition, all weigh factors in the system of dipole antennas were assumed as one. A various techniques of SAR optimization are reported in topic literature, including, among others, the optimal constrained power focusing [13], the time reversal method for power absorption focusing [11], E-field focusing [16], and many similar ones [10].…”

Section: Problem Optimizationmentioning

confidence: 99%

“…According to bioheat equation, the requested temperature levels of given tissue are connected with corresponding specific absorption rate (SAR) values [14]. Very often, for locoregional tissue heating the single dipole antenna [6], their arrays [15], as well as more complex antenna matrixes [9,11,13,16] are successfully utilized.…”

Section: Introductionmentioning

confidence: 99%

SAR optimization for multi-dipole antenna array with regard to local hyperthermia

Gas¹

2019

ELECTROTECHNICAL REVIEW

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The following paper describes the valid optimization problem of multi-element circular array that contains 16 equal-length dipole antennas surrounding given two-spherical object. The task of the authors was to maximize the specific absorption rate (SAR) inside the inner object, while maintaining its minimum value in the external sphere. The proposed approach includes changes in the powers and phases of the voltage sources supplying individual dipoles of the antenna matrix. The shown method may have huge impact in localized tumor heating during thermal therapy. Streszczenie. Niniejsza praca opisuje ważny problem optymalizacji wieloelementowego szyku kołowego, który zawiera 16 anten dipolowych, o równej długości, otaczających dwu-sferyczny obiekt. Zadaniem autorów była maksymalizacja współczynnika absorpcji własnej (SAR) w wewnętrznym obiekcie, przy zachowaniu jego minimalnej wartości w zewnętrznej kuli. Zaproponowane podejście uwzględnia zmiany mocy i faz źródeł napięciowych zasilających poszczególne dipole szyku antenowego. Przedstawiona metoda może mieć olbrzymi wpływ na zlokalizowane grzanie guza podczas terapii ciepłem. (Optymalizacja współczynnika SAR dla szyku z wieloma antenami dipolowymi pod kątem hipertermii miejscowej)

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Design of Site‐Specific Microwave Phased Array Hyperthermia Applicators Using 434 MHz Reduced Cavity‐Backed Patch Antenna

Baskaran

Arunachalam

2020

Bioelectromagnetics

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Cancers of the neck, breast, and lower extremities are common malignancies diagnosed in India with a higher incidence of advanced-stage disease. Phased array (PA) applicators reported for hyperthermia treatment (HT) of the breast have small focal region and high cross-coupling, and those reported for lower extremities provide regional heating and limited steering. In this study, we present the numerical design of site-specific PA applicators for HT of large solid tumors in the neck, breast, and lower extremities using a miniaturized 434 MHz cavity-backed water-loaded patch antenna. The fabricated antenna has 38 × 36 mm 2 aperture, more than 90% power coupling, 25 MHz bandwidth, and good agreement between simulated and measured specific absorption rate (SAR) in phantom. The site-specific applicators demonstrated less power reflection (<−17.9 dB) and crosscoupling (<−26.8 dB) for 5 mm interring spacing. SAR indicators for 64 cc tumor at varying locations in simplified layered three-dimensional (3D) tissue models of the neck, breast, and leg showed average power absorption ratio (aPA ratio) ≥ 3.16, target to hotspot quotient (THQ) ≥ 0.57, 25% iso-SAR coverage (TC 25) ≥ 81%, and 50% iso-SAR coverage (TC 50) ≥51.8%. Simulation results of site-specific applicators for 3D inhomogeneous patient models showed aPA ratio ≥ 5.98, THQ ≥ 0.9, TC 50 ≥ 86%, and 100% TC 25 for all sites. It is concluded that the 434 MHz miniaturized cavity-backed patch antenna can be used to develop high-density PA applicators with 12-24 antennas for HT of large solid tumors (≥4 cm) in the neck, breast, and lower extremities with 3D steering ability and less cross-coupling (

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Design and characterisation of a phased antenna array for intact breast hyperthermia

Abstract: Computational models and experimental results suggest that the proposed applicator may have potential for delivering conformal thermal therapy in the intact breast.

Cited by 30 publications

References 49 publications

Applying a repetitive time‐reversal method to reduce input power of a wearable hyperthermia applicator for breast cancer treatment

Applying a repetitive time‐reversal method to reduce input power of a wearable hyperthermia applicator for breast cancer treatment

SAR optimization for multi-dipole antenna array with regard to local hyperthermia

Design of Site‐Specific Microwave Phased Array Hyperthermia Applicators Using 434 MHz Reduced Cavity‐Backed Patch Antenna

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