Design and baseline characteristics of the Food4Me study: a web-based randomised controlled trial of personalised nutrition in seven European countries

Celis-Morales, Carlos; Livingstone, Katherine M.; Marsaux, Cyril F. M.; Forster, Hannah; O'Donovan, C.B.; Woolhead, Clara; Macready, Anna L.; Fallaize, Rosalind; Navas-Carretero, Santiago; San-Cristóbal, Rodrigo; Kolossa, Silvia; Hartwig, Kai; Tsirigoti, Lydia; Lambrinou, Christina P.; Moschonis, George; Godlewska, Magdalena; Surwiłło, Agnieszka; Grimaldi, Keith; Bouwman, Jildau; Daly, Eoin; Akujobi, Victor; O’Riordan, Rick; Hoonhout, Jettie; Claassen, Arjan; Hoeller, Ulrich; Gundersen, Thomas E.; Kaland, Siv E.; Matthews, J. N. S.; Μanios, Yannis; Traczyk, Iwona; Drevon, Christian A.; Gibney, Eileen R.; Brennan, Lorraine; Walsh, Marianne C.; Lovegrove, Julie A.; Martínéz, J. Alfredo; Saris, Wim H. M.; Daniel, Hannelore; Gibney, Mike; Mathers, John C.

doi:10.1007/s12263-014-0450-2

Cited by 141 publications

(241 citation statements)

References 32 publications

Supporting

Mentioning

239

Contrasting

Order By: Relevance

“…The present VS was performed in a subsample of the Food4Me PoP study, a four-arm, internet-based RCT conducted across seven European countries on the efficacy of PN approaches on health-related outcomes (Celis-Morales et al 2014).…”

Section: Methodsmentioning

confidence: 99%

“…The Food4Me PoP study protocol has been described in detail (Celis-Morales et al 2014). In brief, participants across seven European countries were recruited via the internet to emulate an internet-based PN service.…”

Section: Design Of the Proof Of Principle Studymentioning

confidence: 99%

“…The Food4Me study, an internet-based randomised controlled trial (RCT) conducted across seven European countries, was designed to test the efficacy of personalised nutrition (PN) approaches on health-related outcomes (Celis-Morales et al 2014). Using data from the Food4Me study, the present paper introduces a novel approach for validating participant identity and describes outcomes from a VS to assess the validity of internet-based, SR anthropometric, demographic and identity data, compared with standardised measurements performed face-to-face.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

How reliable is internet-based self-reported identity, socio-demographic and obesity measures in European adults?

et al. 2015

Self Cite

View full text Add to dashboard Cite

In e-health intervention studies, there are concerns about the reliability of internet-based, self-reported (SR) data and about the potential for identity fraud. This study introduced and tested a novel procedure for assessing the validity of internet-based, SR identity and validated anthropometric and demographic data via measurements performed face-to-face in a validation study (VS). Participants (n = 140) from seven European countries, participating in the Food4Me intervention study which aimed to test the efficacy of personalised nutrition approaches delivered via the internet, were invited to take part in the VS. Participants visited a research centre in each country within 2 weeks of providing SR data via the internet. Participants received detailed instructions on how to perform each measurement. Individual's identity was checked visually and by repeated collection and analysis of buccal cell DNA for 33 genetic variants. Validation of identity using genomic information showed perfect concordance between SR and VS. Similar results were found for demographic data (age and sex verification). We observed strong intra-class correlation coefficients between SR and VS for anthropometric data (height 0.990, weight 0.994 and BMI 0.983). However, internet-based SR weight was under-reported (D -0.70 kg [-3.6 to 2.1], p \ 0.0001) and, therefore, BMI was lower for SR data (D -0.29 kg m -2 [-1.5 to 1.0], p \ 0.0001). BMI classification was correct in 93 % of cases. We demonstrate the utility of genotype information for detection of possible identity fraud in e-health studies and confirm the reliability Carlos Celis-Morales and Katherine M. Livingstone have contributed equally to this work.On behalf of the Food4Me Study.Mention of trade names or commercial products in this publication is solely for the purpose of providing specific information and does not imply recommendation or endorsement by the U.S. Department of Agriculture. The USDA is an equal opportunity provider and employer. Electronic supplementary material 123Genes Nutr (2015) 10:28 DOI 10.1007/s12263-015-0476-0 of internet-based, SR anthropometric and demographic data collected in the Food4Me study.Trial registration: NCT01530139 (http://clinicaltrials.gov/ show/NCT01530139).

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Design Of the Proof Of Principle Studymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

How reliable is internet-based self-reported identity, socio-demographic and obesity measures in European adults?

et al. 2015

Self Cite

View full text Add to dashboard Cite

show abstract

“…Participants in the low intensity group 96 received personalised feedback three times during the intervention (at baseline, month 3 and 97 month 6), whereas those randomized to the high intensity group received personalised 98 feedback five times during the intervention (at baseline and months 1, 2, 3 and 6). In addition, 99 the high intensity group had access to an online forum for discussion of topics related to the 100 intervention, personalised recipes and had more personalised feedback on PA. Further details 101 of the Food4Me PoP study are provided elsewhere (17) . Table 1).…”

Section: Introductionmentioning

confidence: 99%

Characteristics of European adults who dropped out from the Food4Me Internet-based personalised nutrition intervention

Livingstone

Celis‐Morales

Macready

et al. 2016

Public Health Nutr.

Self Cite

View full text Add to dashboard Cite

This article has been published in a revised form in Public Health Nutrition [http://dx.doi.org/10.1017/S1368980016002020. This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. ?? 2016 The Authors.OBJECTIVE: To characterise participants who dropped out of the Food4Me Proof-of-Principle study. DESIGN: The Food4Me study was an Internet-based, 6-month, four-arm, randomised controlled trial. The control group received generalised dietary and lifestyle recommendations, whereas participants randomised to three different levels of personalised nutrition (PN) received advice based on dietary, phenotypic and/or genotypic data, respectively (with either more or less frequent feedback). SETTING: Seven recruitment sites: UK, Ireland, The Netherlands, Germany, Spain, Poland and Greece. SUBJECTS: Adults aged 18-79 years (n 1607). RESULTS: A total of 337 (21 %) participants dropped out during the intervention. At baseline, dropouts had higher BMI (0??5 kg/m2; P<0??001). Attrition did not differ significantly between individuals receiving generalised dietary guidelines (Control) and those randomised to PN. Participants were more likely to drop out (OR; 95 % CI) if they received more frequent feedback (1??81; 1??36, 2??41; P<0??001), were female (1??38; 1??06, 1??78; P=0??015), less than 45 years old (2??57; 1??95, 3??39; P<0??001) and obese (2??25; 1??47, 3??43; P<0??001). Attrition was more likely in participants who reported an interest in losing weight (1??53; 1??19, 1??97; P<0??001) or skipping meals (1??75; 1??16, 2??65; P=0??008), and less likely if participants claimed to eat healthily frequently (0??62; 0??45, 0??86; P=0??003). CONCLUSIONS: Attrition did not differ between participants receiving generalised or PN advice but more frequent feedback was related to attrition for those randomised to PN interventions. Better strategies are required to minimise dropouts among younger and obese individuals participating in PN interventions and more frequent feedback may be an unnecessary burden

show abstract

“…Several methods were used to assess dietary intake of SSB in the identified studies, but most used FFQ (n 24) (47,51,54,56,(59)(60)(61)(62)(63)(64)(65)67,69,(71)(72)(73)76,82,101,103,107,110,121) . Other methods identified through the review were 24 h recalls (24-HDR; n 6) (48,51,52,78,113,122) and diet records/diet diaries (102) .…”

Section: Types Of Methodsmentioning

confidence: 99%

A systematic review of methods to assess intake of sugar-sweetened beverages among healthy European adults and children: a DEDIPAC (DEterminants of DIet and Physical Activity) study

Riordan

Ryan

Perry

et al. 2016

Public Health Nutr.

View full text Add to dashboard Cite

Research indicates that intake of sugar-sweetened beverages (SSB) may be associated with negative health consequences. However, differences between assessment methods can affect the comparability of intake data across studies. The current review aimed to identify methods used to assess SSB intake among children and adults in pan-European studies and to inform the development of the DEDIPAC (DEterminants of DIet and Physical Activity) toolbox of methods suitable for use in future European studies. A literature search was conducted using three electronic databases and by hand-searching reference lists. English-language studies of any design which assessed SSB consumption were included in the review. Studies involving two or more European countries were included in the review. Healthy, free-living children and adults. The review identified twenty-three pan-European studies which assessed intake of SSB. The FFQ was the most commonly used (n 24), followed by the 24 h recall (n 6) and diet records (n 1). There were several differences between the identified FFQ, including the definition of SSB used. In total, seven instruments that were tested for validity were selected as potentially suitable to assess SSB intake among adults (n 1), adolescents (n 3) and children (n 3). The current review highlights the need for instruments to use an agreed definition of SSB. Methods that were tested for validity and used in pan-European populations encompassing a range of countries were identified. These methods should be considered for use by future studies focused on evaluating consumption of SSB

show abstract

Design and baseline characteristics of the Food4Me study: a web-based randomised controlled trial of personalised nutrition in seven European countries

Cited by 141 publications

References 32 publications

How reliable is internet-based self-reported identity, socio-demographic and obesity measures in European adults?

How reliable is internet-based self-reported identity, socio-demographic and obesity measures in European adults?

Characteristics of European adults who dropped out from the Food4Me Internet-based personalised nutrition intervention

A systematic review of methods to assess intake of sugar-sweetened beverages among healthy European adults and children: a DEDIPAC (DEterminants of DIet and Physical Activity) study

Contact Info

Product

Resources

About