Design and 3D printing of a stainless steel reactor for continuous difluoromethylations using fluoroform

Abstract

The design and 3D printing of a stainless steel reactor for reaction with a gaseous reagent is described.

Energy and Resource Efficient Production of Fluoroalkenes in High Temperature Microreactors

“…The reasons for this trend are safer handling of hazardous reactants, a reduction in the (potential) exposure to toxic or hazardous chemical species, and higher process safety in terms of thermal runaway by efficient cooling. Moreover, the application of microreactors in fluorine containing reactions is beneficial in terms of reduced reaction volume, optimal process conditions, and thus higher yields of target products [19,20]. Scale-up of a microreactor process can be easily done just by numbering up [21].…”

“…In the Equations (20) and 21, u is the gas velocity, and d t and L t are the diameter and length of the reactor, respectively. The Bodenstein number Bo represents the ratio of convective flux to diffusive flux [28]:…”

Design and construction of an open source-based photometer and its applications in flow chemistry

“…We have recently published the design and fabrication of a 3D printed stainless steel flow reactor specifically made for a low-temperature two-step continuous deprotonation/ difluoromethylation process. 28 The reactor design and mixing geometry was optimized for this process with channels being slightly oval in the cross section, affording better surface quality after the 3D printing process. The 4 m in total of reaction channels (0.8 mm i.d., ca.…”

“…Computational fluid dynamics was used to predict the mixing performace of the reactor. 28 Measuring the RTD with a step experiment (RB dye) at 1 mL min −1 suggests moderate axial diffusion through the reactor (Fig. S23 †).…”

Momentum, heat and mass transfer simulations of bounded dense mono-dispersed gas-particle systems

“…Other applications include blood flow in the human body, sediment transport in river beds and pyroclastic flows from vulcanos. Current developments indicate that the confinement effect in suspension flows becomes even more important: for example, so-called '3D printing' technology aiming on producing materials capable to be used at high temperatures (e.g., metals or ceramics) is already reality [1]. This enables the use of complex geometries with characteristic dimensions closer to that of the suspended particles.…”