Descrição morfológica e morfométrica da glândula vesicular de cobaias durante o desenvolvimento pós-natal

Abstract

Pesq. Vet. Bras. 33(7): 942-948, julho 2013 942 RESUMO.-Glândulas vesiculares são essenciais para a reprodução, pois suas secreções afetam a função espermá-tica. Cobaias (Cavia porcellus) são um excelente modelo experimental para estudo destas glândulas, contudo não existem dados morfológicos e morfométricos durante seu desenvolvimento. Neste estudo a morfologia (projeções das pregas (PP) e altura das células epiteliais (AE) da tú-nica mucosa) e a morfometria (massa (MG), volume (VG), comprimento (CG), largura das porções cranial (LCR), mé-dia (LM) e caudal (LCA)) das glândulas vesiculares foram determinadas em cobaios (N= 25) com uma (S1), três (S3), (Cavia porcellus) are an excellent experimental model for studying vesicular glands, but no morphologic and morphometric data during its development are available. In the present study, the morphology (projections of the folds (PF) and epithelial tissue high (EH) of the mucosa) and the morphometry (mass (GM), volume (GV), length (GC), width of the portions cranial (CRW), medium (MW) and caudal (CAW)) of the vesicular glands were determined at 1, 3, 5, 8, and 11-weeks of age in male guinea pigs (n = 5/age group). In addition, body mass (BM), body length (BL) and height (BH) and organo-somatic index (OSI) were also determined and the simple correlation coefficient (r) was established between the variables. The glands were restricted to the pelvic cavity, and had its interior filled with a semi-solid mass and, after S8, they occupied also the abdominal cavity and the contents were increased significantly. The mucous membrane presented variable folding and simple columnar epithelium. BM, BL and BH increased continuously with age. GM, GV, GC and CAW did not change from 1 to 5-weeks of age, but increased at 8-weeks of age; GM, GV and LCA also increased at 11-weeks of age. OSI and PF increased at 8 and 11-weeks of age and EH at 5, 8 and 11-weeks of age. There was significant (r) between age, body and glandular parameters; OSI and GM at 8 and 11-weeks of age; age and PF, age and EH and between PF and EH. In conclusion, the guinea pigs vesicular glands followed morphology observed in rats and hamsters, but differed in some aspects from others histricomorfs, can be used as experimental model and its morphological and morphometric development can be divided into three phases: 1 to 5-weeks of age, when they are discrete; 6 to 8-weeks of age when they are generally sharp and >8-weeks of age, when there is an intense increase of the secretory capacity.

The Effect of Kuchala (Arum Korolkowii Regel, 1873) Tuber Tincture to Increase of the Serum Testosterone in the Adult Male Guinea Pigs (Cavia Porcellus Linnaeus, 1758)

“…For this purpose, we analyzed the literature data and found that among different laboratory animal's guinea pig has many morphofunctional similarities with human, namely by the lung physiology [24], hormonal, immunological and corticosteroid responses [13,14]. Importantly, the guinea pig has many common features with human reproduction -by presenting of the accessory glands [16,17], characteristics of the placenta [25], morphological and functional analysis of spermatogenesis [26]. Besides, it has available information that the content of testosterone and androstenedione in serum and testis were different in guinea pigs in the prenatal [20,27], and postnatal [28] periods.…”

Ultrastructural analysis of the spermatogenesis in the guinea pig (Cavia porcellus)

“…Finally, as demonstrated by Nunes et al (2013), the Cavia porcellus in post-pubertal stage 2 are an advantageous experimen tal model to address studies on the processes of homologous recognition, alignment, and synapsis during meiotic prophase, as well as for other topics related to male reproductive characteristics.…”

“…The physiology of the reproductive system of the male guinea pig has been insufficiently described. Especially related to the guinea pig, there are some gaps in the literature regarding to the morphology and ultrastructure of the testis, although there are some studies focusing on quantification of cell types at different sexual stages (Hess & França 2008), accessory glands (Váquez & Del Sol, 2010, Gradela et al 2013), effects of electromagnetic fields on testis (Farkhad et al 2007), and more recently the effects of fluoride and aluminum in the expression of StAR and P450scc in the testis (Dong et al 2016).…”

Participation of the Intercostal Nerves to the Innervation of the Diaphragm Muscle in Cavia porcellus

“…It is frequently used for studies on the anatomy and physiology that shall be applied to the humans and other species. [21][22][23] Even with the diaphragm being responsible for such an essential function as breathing, there are no studies on the role of the intercostal nerves to its innervation in guinea pigs.…”