Dermoscopy of Atypical Dermatofibroma

Zaballos, Pedro; Puig, Susana; Malvehy, Josep

doi:10.1001/archderm.142.1.126

Cited by 14 publications

(9 citation statements)

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“…Our dermatopathological correlations of dermatoscopy findings such as reticular lines, white structureless areas, white reticular lines, structureless colored areas, circle‐clod structures, and thick curved lines were similar to those observed in previous studies …”

Section: Discussionsupporting

confidence: 90%

Dermatopathological characteristics of dermatofibromas from dermatoscopic clues

et al. 2019

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Background Several types of dermatofibroma (DF) have been identified dermatopathologically and with dermatoscopic correlation, the dermatopathology has been predictable in limited studies so far. We identify DFs with specific dermatoscopic structures and determine the respective dermatopathological correlates. Methods Dermatoscopic and dermatopathologic correlation of 403 DFs were assessed. A pattern analysis algorithm was used for the dermatoscopic evaluation, each lesion being evaluated according to 10 dermatoscopic patterns with further subdivision of the atypical subtype according and their dermatoscopic similarities to other defined skin lesions. Results Dermatoscopic pattern analysis showed typical patterns in 83.4% of DFs with atypical patterns in 16.6%. We classified the atypical DFs according to their dermatoscopic similarity to certain lesions: Melanoma‐like 2.7%, basal cell carcinoma‐like 0.7%, keratoacanthoma‐like 0.5%, seborrheic keratosis‐like 2.7%; nevus‐like 1.5%; nevus sebaceous‐like 0.9%; xanthogranuloma‐like 0.5%; pyogenic granuloma‐like 0.5%; and spitzoid 6.5%. Dermatopathologically 12 subtypes of DFs were identified. It was found that the most common pattern found in fibrocollagenous DFs was the typical pattern with peripheral reticular lines and central white structureless area (32.9%) whereas non‐fibrocollagenous types were more likely to have atypical patterns (65.1%). Conclusions Our study resulted in new conclusions while supporting some previous findings. The fact that the pathogenesis of DF involves a reactive inflammatory process with fibrosis is likely to have diverse effects on dermatoscopic morphology. If atypical dermatoscopic patterns are identified in suspected DF, excisional biopsy may be prudent.

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Section: Discussionsupporting

confidence: 90%

Dermatopathological characteristics of dermatofibromas from dermatoscopic clues

et al. 2019

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“…The most frequent variant of dermatofibroma was fibrocollagenous type (n = 98, 49%) followed by sclerotic (n = 38, 19%), histiocytic (n = 26, 13%) and cellular (n = 16, 8%) (Figs. [3][4][5][6][7][8][9][10]. The depth of 59.5% of the samples was dermis.…”

Section: Histopathological Findingsmentioning

confidence: 99%

“…10 different dermatoscopic patterns were reported. Although there are several studies examining histopathology or dermatoscopy of dermatofibromas separately the literature lacks a study investigating both in the same patient group. In the present study, we aimed to analyse histopathological, dermatoscopic and digital microscopic features of dermatofibromas.…”

mentioning

confidence: 99%

Clinical, histopathological, dermatoscopic and digital microscopic features of dermatofibroma: a retrospective analysis of 200 lesions

Şenel

Karabulut

Şenel

2015

Acad Dermatol Venereol

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“…High sensitivities and specificities especially for the distinction of melanocytic nevi from malignant melanoma can be reached by using established scoring schemes (3)(4)(5). For many other entities such as benign and malignant neoplasias (6,7) inflammatory disorders (8,9) and skin infections (10,11) and infestations (12,13), dermatoscopic criteria were described. Another special indication for dermoscopy is the microscopic evaluation of the nailfold, mainly in autoimmune diseases, whereby vascular changes are usually seen in early stages (14,15).…”

Section: Dermoscopymentioning

confidence: 99%

Clinical application of multiphoton tomography in combination with confocal laser scanning microscopy for in vivo evaluation of skin diseases

Koehler

Speicher

Lange‐Asschenfeldt

et al. 2011

Experimental Dermatology

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Multiphoton tomography (MPT) is an in vivo imaging technique with very high spatial resolution and efforts are made to combine MPT with other non-invasive imaging methods. The goals of the present study were the description of the features of different dermatological entities as seen in MPT and confocal laser scanning microscopy (CLSM) comparison of these two novel techniques and the 'classical' diagnostic measures visual inspection, dermoscopy and histology with respect to the strengths and weaknesses of the different methods and the potential benefit from their combined implementation. After study approval by the local Ethics Committee, 47 patients (31 male, 16 female, age range: 24-88 years) were recruited from the Department of Dermatology of the University Hospital Jena. In this work, we present an illustrative selection of eleven cases from a clinical study combining in vivo MPT with in vivo CLSM. The patients presented with a broad range of dermatological disorders including seborrheic keratoses, angioma, actinic keratoses, melanocytic nevi, malignant melanoma, psoriasis, pemphigus vulgaris and scarring. Both methods, CLSM and MPT, were found to be suitable for in vivo imaging of superficial skin layers and may therefore be useful in dermatological practice for the diagnosis of skin diseases. However, both methods differ in their technical and physical principles. Thus, despite of many similarities concerning the morphological presentation of cells and tissues, important differences are recognized. Synergies of the combination of CLSM and MPT may be obtained by combined implementation in order to benefit from the fast overview given by CLSM and the detailed imaging of skin structures by MPT.

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Dermoscopy of Atypical Dermatofibroma

Cited by 14 publications

References 0 publications

Dermatopathological characteristics of dermatofibromas from dermatoscopic clues

Dermatopathological characteristics of dermatofibromas from dermatoscopic clues

Clinical, histopathological, dermatoscopic and digital microscopic features of dermatofibroma: a retrospective analysis of 200 lesions

Clinical application of multiphoton tomography in combination with confocal laser scanning microscopy for in vivo evaluation of skin diseases

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