Dermoscopic characteristics of microcystic adnexal carcinoma, desmoplastic trichoepithelioma, and morpheaform basal cell carcinoma

Costello, Collin M.; Han, Maggie; Severson, Kevin J.; Maly, Connor; Yonan, Yousif; Nelson, Sara; Swanson, David L.; Mangold, Aaron R.

doi:10.1111/ijd.15040

Cited by 7 publications

(4 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…O diagnóstico do CBC esclerodermiforme é desafiador e tardio dentro da população, em virtude dos vários subtipos histológicos de CBC existentes e por apresentar manifestações clínicas semelhantes. Assim, é necessário usar a dermatoscopia como uma ferramenta auxiliar para atingir um diagnóstico satisfatório (COSTELLO et al, 2021).…”

Section: Resultsunclassified

Carcinoma basocelular esclerodermiforme

Mattos,

Koyama,

Camargo

et al. 2024

ROS

View full text Add to dashboard Cite

Este trabalho buscou verificar a incidência do carcinoma basocelular (CBC) esclerodermiforme, caracterizado como tumor cutâneo, que apresenta caráter infiltrativo, elevadas taxas de recorrências e pior prognóstico, acometendo mais o sexo feminino e a região de cabeça e pescoço. A exposição solar é o fator de risco mais comum para o desencadeamento do CBC esclerodermiforme, com predomínio em pessoas com 70 anos de idade ou mais, pois a exposição à radiação ultravioleta é acumulativa ao longo da vida. O diagnóstico é clínico, mas o auxílio da dermatoscopia é essencial. Entretanto, é um desafio diagnosticar precocemente o CBC esclerodermiforme devido a suas características imprecisas. O tratamento mais indicado é o cirúrgico, especialmente a cirurgia micrográfica de Mohs, pois é considerada a mais precisa. Além da técnica cirúrgica, podem ser associadas quimioterapia e radioterapia. Alguns tumores são extensos e invasivos, podendo causar desconfigurações estéticas no paciente, que pode precisar de cirurgias reconstrutoras depois.

show abstract

Section: Resultsunclassified

Carcinoma basocelular esclerodermiforme

Mattos,

Koyama,

Camargo

et al. 2024

ROS

View full text Add to dashboard Cite

show abstract

“…Costello et al [ 12 ], in a recently published case series, analysed dermoscopic features of four DT cases which revealed polymorphous vessels (2/4), linear serpentine vessels (2/2), circular white structures (4/4), and shiny white structures (1/4). In a study by Ghigliotti et al [ 6 ], no statistical significance was found between the presence of arborizing vessels in the TB (95%) and BCC (86%) groups, and the presence of chrysalis structures (16 vs. 21%, respectively).…”

Section: Discussionmentioning

confidence: 99%

Significance of Dermoscopy in Association with Clinical Features in Differentiation of Basal Cell Carcinoma and Benign Trichoblastic Tumours

Sławińska

Płaszczyńska

Lakomy

et al. 2022

Cancers

View full text Add to dashboard Cite

Background: Although basal cell carcinoma (BCC) can, in the majority of cases, be diagnosed based on clinical and dermoscopic assessment, a potential overlap with benign adnexal skin tumours seems to exist, including trichoblastic tumours (TT). Methods: Retrospective analysis of clinical and dermoscopic features of benign TT and BCC cases was performed to develop a diagnostic algorithm with a potential utility in clinical practice. Results: In the study, 502 histopathologically confirmed BCC cases were compared with 61 TT (including 44 TB (72.13%), 10 TE (16.39%) and 7 DTE (11.48%]). Patients in the BCC group were statistically older (mean age was 71.4 vs. 64.4 years, respectively; p = 0.009). BCC presented generally as larger tumours (mean tumour size 11.0 vs. 8.2 mm for the TT group; p = 0.001) and was more frequently associated with clinically visible ulceration (59.4% vs. 19.7%, respectively; p < 0.001). Comparison of lesion morphology, clinically visible pigmentation, and anatomical location did not show significant differences between the analysed groups. Dermoscopically visible ulceration was significantly more common in the BCC group compared to the TT group (52.2% vs. 14.8%; p < 0.0001). Pigmented structures, specifically brown dots and brown globules, were significantly more prevalent in the TT group (32.8% vs. 11.4%; p = 0.0001 and 29.5% vs. 8.2%; p <0.0001). Similarly, TT more commonly than BCC showed the presence of cloudy/starry milia-like cysts (26.2% vs. 11.6%; p = 0.0031) and yellow globules (16.4% vs. 7.2%; p = 0.033). Conclusions: Despite differences in frequency of clinical and dermoscopic features between BCC and TT in the studied group, differential diagnosis based on these variables is not reliable. Histopathological examination remains a diagnostic gold standard in differentiation of BCC and TT.

show abstract

“…A recent case series found circular white structures in DTE and microcystic adnexal carcinoma. [ 5 ] These structures represented calcification and keratin cysts within the tumor. However, mBCC can also have calcification and keratin cysts rarely and hence dermoscopy alone cannot differentiate DTE, mBCC, and microcystic adnexal carcinoma.…”

Section: Discussionmentioning

confidence: 99%