Dermatomyositis Without Muscle Weakness

Dermatomyositis without muscle weakness associated with transitional cell carcinoma of the bladder

“…There have been reports of cases of ADM associated with an underlying malignancy, including lymphoma, 7 carcinoma of the lung, ovary, uterus, 8 breast, 2,6,7 colon, 4 kidney 7 and nasopharynx 9 . Bladder carcinoma is less frequently encountered in association with DM, 10 and to the best of our knowledge, the association of DM without muscle weakness, and transitional cell carcinoma of the bladder has not been reported previously.…”

“…Cutaneous lesions may often precede clinical myositis and muscle weakness develops 3–6 months later in most patients. However, in some patients, muscle disease does not develop or appears to be minor or transient 1–3 . Therefore, the term ‘amyopathic DM’ (ADM), as described by Euwer and Sontheimer, is used to refer to patients who have classical cutaneous findings without clinical or enzymatic evidence of muscle disease for at least 2 years 1 .…”

“…Therefore, the term ‘amyopathic DM’ (ADM), as described by Euwer and Sontheimer, is used to refer to patients who have classical cutaneous findings without clinical or enzymatic evidence of muscle disease for at least 2 years 1 . Cosnes et al 2 . designated their cases as DM without muscle weakness.…”

“…However, controversy still exists concerning the definition of muscle disease. Those subjects who do not have overt muscle weakness or abnormal laboratory parameters are sometimes considered to be ADM 1–3 . On the contrary, some authors believe that the presence of minimal muscle involvement is inconsistent with the diagnosis of ADM 4,5 .…”

Dermatomyositis without muscle weakness associated with transitional cell carcinoma of the bladder

“…There have been reports of cases of ADM associated with an underlying malignancy, including lymphoma, 7 carcinoma of the lung, ovary, uterus, 8 breast, 2,6,7 colon, 4 kidney 7 and nasopharynx 9 . Bladder carcinoma is less frequently encountered in association with DM, 10 and to the best of our knowledge, the association of DM without muscle weakness, and transitional cell carcinoma of the bladder has not been reported previously.…”

“…Cutaneous lesions may often precede clinical myositis and muscle weakness develops 3–6 months later in most patients. However, in some patients, muscle disease does not develop or appears to be minor or transient 1–3 . Therefore, the term ‘amyopathic DM’ (ADM), as described by Euwer and Sontheimer, is used to refer to patients who have classical cutaneous findings without clinical or enzymatic evidence of muscle disease for at least 2 years 1 .…”

“…Therefore, the term ‘amyopathic DM’ (ADM), as described by Euwer and Sontheimer, is used to refer to patients who have classical cutaneous findings without clinical or enzymatic evidence of muscle disease for at least 2 years 1 . Cosnes et al 2 . designated their cases as DM without muscle weakness.…”

“…However, controversy still exists concerning the definition of muscle disease. Those subjects who do not have overt muscle weakness or abnormal laboratory parameters are sometimes considered to be ADM 1–3 . On the contrary, some authors believe that the presence of minimal muscle involvement is inconsistent with the diagnosis of ADM 4,5 .…”

A Rare Lymphoma in a Patient with Amyopathic Dermatomyositis

“…[9] Other malignancies reported with amyopathic dermatomyositis include ovarian, endometrial, and cervical cancer in women, nasopharyngeal carcinoma in Asian populations, gastointestinal malignancies, and melanoma. [4,10,11,[15][16][17][18] One review used two cases to exemplify that even microscopic foci of a tumor can mediate paraneoplastic manifestations. A patient with colon adenocarcinoma and a patient with bladder carcinoma received unremarkable evaluations at the onset of their cutaneous symptoms, only to be diagnosed on repeat evaluation several months later.…”

Dermatomyositis without muscle weakness associated with transitional cell carcinoma of the bladder

“…There have been reports of cases of ADM associated with an underlying malignancy, including lymphoma, 7 carcinoma of the lung, ovary, uterus, 8 breast, 2,6,7 colon, 4 kidney 7 and nasopharynx 9 . Bladder carcinoma is less frequently encountered in association with DM, 10 and to the best of our knowledge, the association of DM without muscle weakness, and transitional cell carcinoma of the bladder has not been reported previously.…”

“…Cutaneous lesions may often precede clinical myositis and muscle weakness develops 3–6 months later in most patients. However, in some patients, muscle disease does not develop or appears to be minor or transient 1–3 . Therefore, the term ‘amyopathic DM’ (ADM), as described by Euwer and Sontheimer, is used to refer to patients who have classical cutaneous findings without clinical or enzymatic evidence of muscle disease for at least 2 years 1 .…”

“…Therefore, the term ‘amyopathic DM’ (ADM), as described by Euwer and Sontheimer, is used to refer to patients who have classical cutaneous findings without clinical or enzymatic evidence of muscle disease for at least 2 years 1 . Cosnes et al 2 . designated their cases as DM without muscle weakness.…”

“…However, controversy still exists concerning the definition of muscle disease. Those subjects who do not have overt muscle weakness or abnormal laboratory parameters are sometimes considered to be ADM 1–3 . On the contrary, some authors believe that the presence of minimal muscle involvement is inconsistent with the diagnosis of ADM 4,5 .…”

A Rare Lymphoma in a Patient with Amyopathic Dermatomyositis

“…[9] Other malignancies reported with amyopathic dermatomyositis include ovarian, endometrial, and cervical cancer in women, nasopharyngeal carcinoma in Asian populations, gastointestinal malignancies, and melanoma. [4,10,11,[15][16][17][18] One review used two cases to exemplify that even microscopic foci of a tumor can mediate paraneoplastic manifestations. A patient with colon adenocarcinoma and a patient with bladder carcinoma received unremarkable evaluations at the onset of their cutaneous symptoms, only to be diagnosed on repeat evaluation several months later.…”

Dermatomyositis without muscle weakness associated with transitional cell carcinoma of the bladder

“…There have been reports of cases of ADM associated with an underlying malignancy, including lymphoma, 7 carcinoma of the lung, ovary, uterus, 8 breast, 2,6,7 colon, 4 kidney 7 and nasopharynx 9 . Bladder carcinoma is less frequently encountered in association with DM, 10 and to the best of our knowledge, the association of DM without muscle weakness, and transitional cell carcinoma of the bladder has not been reported previously.…”

“…Cutaneous lesions may often precede clinical myositis and muscle weakness develops 3–6 months later in most patients. However, in some patients, muscle disease does not develop or appears to be minor or transient 1–3 . Therefore, the term ‘amyopathic DM’ (ADM), as described by Euwer and Sontheimer, is used to refer to patients who have classical cutaneous findings without clinical or enzymatic evidence of muscle disease for at least 2 years 1 .…”

“…Therefore, the term ‘amyopathic DM’ (ADM), as described by Euwer and Sontheimer, is used to refer to patients who have classical cutaneous findings without clinical or enzymatic evidence of muscle disease for at least 2 years 1 . Cosnes et al 2 . designated their cases as DM without muscle weakness.…”

“…However, controversy still exists concerning the definition of muscle disease. Those subjects who do not have overt muscle weakness or abnormal laboratory parameters are sometimes considered to be ADM 1–3 . On the contrary, some authors believe that the presence of minimal muscle involvement is inconsistent with the diagnosis of ADM 4,5 .…”

A Rare Lymphoma in a Patient with Amyopathic Dermatomyositis

“…[9] Other malignancies reported with amyopathic dermatomyositis include ovarian, endometrial, and cervical cancer in women, nasopharyngeal carcinoma in Asian populations, gastointestinal malignancies, and melanoma. [4,10,11,[15][16][17][18] One review used two cases to exemplify that even microscopic foci of a tumor can mediate paraneoplastic manifestations. A patient with colon adenocarcinoma and a patient with bladder carcinoma received unremarkable evaluations at the onset of their cutaneous symptoms, only to be diagnosed on repeat evaluation several months later.…”