Dermatological and musculoskeletal assessment of diabetic foot: A narrative review

Shirazi, Azam Arsanjani; Nasiri, Morteza; Yazdanpanah, Leila

doi:10.1016/j.dsx.2016.03.004

Cited by 13 publications

(12 citation statements)

References 68 publications

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“…Diabetic foot is still the most frequent reason of hospitalization of patients with diabetes [ 7 – 10 ], and diabetes is the main cause of more than half of nontraumatic lower limb amputations [ 11 – 15 ]. In fact, every 30 seconds in the world, a lower limb is amputated due to diabetes [ 16 ], and it goes without saying that these amputations increase mortality rate [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Incidence and Risk Factors of Diabetic Foot Ulcer: A Population-Based Diabetic Foot Cohort (ADFC Study)—Two-Year Follow-Up Study

Yazdanpanah

Shahbazian

Nazari

et al. 2018

International Journal of Endocrinology

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131

104

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Aim/Introduction. This study was carried out to assess the incidence and risk factors of diabetic foot ulcer (DFU). Materials and Methods. In this prospective cohort study in a university hospital, all the participants were examined and followed up for new DFU as final outcome for two years. To analyze the data, the variables were first evaluated with a univariate analysis. Then variables with P value < 0.2 were tested with a multivariate analysis, using backward-elimination multiple logistic regression. Results. Among 605 patients, 39 cases had DFU, so we followed up the remaining 566 patients without any present or history of DFU. A two-year cumulative incidence of diabetic foot ulcer was 5.62% (95% CI 3.89-8.02). After analysis, previous history of DFU or amputation [OR = 9.65, 95% CI (2.13-43.78), P value = 0.003], insulin usage [OR = 5.78, 95% CI (2.37-14.07), P value < 0.01], gender [OR = 3.23, 95% CI (1.33-7.83), P value = 0.01], distal neuropathy [OR = 3.37, 95% CI (1.40-8.09), P value = 0.007], and foot deformity [OR = 3.02, 95% CI (1.10-8.29), P value = 0.032] had a statistically significant relationship with DFU incidence. Conclusion. Our data showed that the average annual DFU incidence is about 2.8%. Independent risk factors of DFU development were previous history of DFU or amputation, insulin consumption, gender, distal neuropathy, and foot deformity. These findings provide support for a multifactorial etiology for DFU.

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Section: Introductionmentioning

confidence: 99%

Incidence and Risk Factors of Diabetic Foot Ulcer: A Population-Based Diabetic Foot Cohort (ADFC Study)—Two-Year Follow-Up Study

Yazdanpanah

Shahbazian

Nazari

et al. 2018

International Journal of Endocrinology

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131

104

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“…Without a prompt and comprehensive assessment, it leads to ulceration and lower limb amputation frequently (6). The antibiotic treatment (antibiotherapy) plays an important role in therapy of these infections.…”

Section: Introductionmentioning

confidence: 99%

Renal function in patients with diabetic foot infection; does antibiotherapy affect it?

et al. 2016

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Introduction: Antibiotic treatment (antibiotherapy) of diabetic foot ulcers has been proven to have toxic effect on renal function. Objectives: This study aimed to evaluate renal function in patients with diabetic foot infection. Patients and Methods: This cross-sectional retrospective study was performed on 142 patients with diabetic foot ulcers hospitalized in Shahid Yahyanejad hospital of Babol during 2013. After referring to profile of the patients, they were assigned to participate in two groups: group A consisted of patients receiving antibiotics with a low risk renal toxicity and patients who received antibiotics with a higher risk of renal toxicity were placed in group B. Glomerular filtration rate (GFR) was measured and calculated based on serum concentration of creatinine and Cockcroft-Gault equation. Data was analyzed using SPSS version 20.0 with chi-square, t test and paired t tests. Results: Group A consisted of 74 patients (52.1%) and 68 patients (47.9%) participated in group B. GFRs before and after antibiotherapy were 64.73±33.87 cc/min and 59.10±30.51 cc/min, respectively (P=0.004). In group B, GFR decreased significantly after antibiotherapy (P=0.002). Conclusion: According to the present study, renal function decreased after antibiotherapy and in patients who received antibiotics with higher nephrotoxicity rate, the rate of this decline was higher.

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“…(Kiani et al, 2014). Diabetes mellitus (DM) ditandai dengan peningkatan kadar glukosa plasma, akibat dari tidak adanya atau sedikit sekresi insulin dengan atau tanpa gangguan bersamaan dari kerja insulin (Arsanjani Shirazi et al, 2016).…”

Section: Pendahuluanunclassified

“…Perkiraan terbaru dari International Diabetes Federation (IDF), menunjukkan tingkat prevalensi global diabetes sebesar 8,4% pada orang dewasa, dan sebanyak 382 juta kasus diabetes pada 2013. Berdasarkan kecenderungan saat ini, diperkirakan angka ini akan berlipat ganda pada tahun 2050 (Boyle et al, 2010;Arsanjani Shirazi et al, 2016). Sekitar 90% pasien diabetes merupakan DM tipe 2, yang ditandai dengan berbagai tingkat resistensi dan defisiensi insulin.…”

Section: Pendahuluanunclassified

Komplikasi Muskuloskeletal pada Pasien Diabetes Melitus

Prakasa

2020

jiskh

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Latar belakang. Selain komplikasi makrovaskular dan mikrovaskuler, pasien diabetes mungkin mengalami beberapa komplikasi muskuloskeletal. Dampak komplikasi muskuloskeletal terhadap kualitas hidup penderita diabetes sangat besar. Terdapat banyak data epidemiologi yang mengaitkan komplikasi ini dengan diabetes, tetapi patogenesis dan faktor penyebab belum dijelaskan lebih lanjut. Oleh karena itu, tujuan dari studi literatur ini adalah untuk mengetahui lebih lanjut komplikasi muskuloskeletal pada pasien diabetes melitus. Metode. Studi ini merupakan literature review, dengan sumber pustaka yang digunakan sebanyak 22 pustaka, berasal dari 1 jurnal nasional dan 21 jurnal internasional. Hasil. Beberapa penelitian menunjukkan komplikasi muskuloskeletal yang sering dijumpai pada penderita diabetes melitus antara lain kapsulitis bahu, sindrom mobilitas sendi terbatas (LJM), kontraktur Dupuytren, carpal tunnel syndrome dan trigger finger. Kerusakan pembuluh dan saraf, glikosilasi protein, dan peningkatan kolagen di kulit dan jaringan ikat muskuloskeletal adalah beberapa faktor yang diduga berkontribusi dalam perkembangan gangguan muskuloskeletal pada penderita diabetes. Kesimpulan. Manifestasi muskuloskeletal dari diabetes sering ditemui, dan meskipun tidak mengancam nyawa, ia merupakan penyebab penting dari morbiditas, nyeri dan kecacatan. Kata Kunci: diabetes melitus, komplikasi, muskuloskeletal

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Dermatological and musculoskeletal assessment of diabetic foot: A narrative review

Cited by 13 publications

References 68 publications

Incidence and Risk Factors of Diabetic Foot Ulcer: A Population-Based Diabetic Foot Cohort (ADFC Study)—Two-Year Follow-Up Study

Incidence and Risk Factors of Diabetic Foot Ulcer: A Population-Based Diabetic Foot Cohort (ADFC Study)—Two-Year Follow-Up Study

Renal function in patients with diabetic foot infection; does antibiotherapy affect it?

Komplikasi Muskuloskeletal pada Pasien Diabetes Melitus

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