Dermatitis Venenata From English Ivy (Hedera Helix)

Goldman, Leon

doi:10.1001/archderm.1956.01550090085020

Cited by 11 publications

(5 citation statements)

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“…The skin‐irritating properties of common ivy were, at that time, already known to gardeners in England . Further reports quickly appeared in the Australian, French and German literature , and then sporadically over the next 40 years from the United States and Spain . More recent patch test studies have shown sensitivity to H. helix in Australia , South Africa , and England .…”

Section: Plant Sources Of Some European Herbal Medicinal Products Andmentioning

confidence: 97%

Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products – Part 2: Echinacea purpurea–Lavandula angustifolia

et al. 2015

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Section: Plant Sources Of Some European Herbal Medicinal Products Andmentioning

confidence: 97%

Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products – Part 2: Echinacea purpurea–Lavandula angustifolia

et al. 2015

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“…Although not commonly known to cause dermatitis, English ivy too has been documented at least twice 3 to have caused dermatitis in the form of linear streaked vesicles resembling poison ivy dermatitis. One of the cases 3 happened in 1954 when an engineer presented with repeated episodes of severe contact dermatitis despite prolonged attempts at oral hyposensitization with tablets with extracts of poison ivy.…”

Section: The Use Of Ivy In Dermatologymentioning

confidence: 99%

“…1 This term is used in intrapatient comparative analysis (IPCA) of nevi and is widely recognized as a major indicator for suspicion of melanoma both visually and dermoscopically. 2,3 We previously demonstrated that the ability of a dermatologist to intuitively perceive a nevus that looks different from others relies on the limited diversity of nevi, which constitutes an individual reference system in each patient. 4 A major benefit for training physicians and facilitating self-detection in the at-risk population may come from understanding the robustness, reliability, and diagnostic effect of the IPCA process using the ugly duckling sign in detection of melanoma.…”

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confidence: 99%

Ugly Duckling Sign as a Major Factor of Efficiency in Melanoma Detection

et al. 2017

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IMPORTANCE Understanding the contribution of the ugly duckling sign (a nevus that is obviously different from the others in a given individual) in intrapatient comparative analysis (IPCA) of nevi may help improve the detection of melanoma.OBJECTIVES To assess the agreement of dermatologists on identification of the ugly duckling sign and estimate the contribution of IPCA to the diagnosis of melanoma. DESIGN, SETTING, AND PARTICIPANTSThe same 2089 digital images of the nevi of a sample of 80 patients (mean age, 42 years [range, 19-80 years]; 33 men and 47 women), as well as 766 dermoscopic images from a subset of 30 patients (mean age, 40 years [range, 21-75 years]; 12 men and 18 women), were randomly presented to the same 9 dermatologists for blinded assessment from September 22, 2011, to April 1, 2013. The first experiment was designed to mimic an IPCA situation, with images of all nevi of each patient shown to the dermatologists, who were asked to identify ugly duckling nevi (UDN). The second experiment was designed to mimic a lesion-focused analysis to identify morphologically suspicious nevi. Data analysis was conducted from MAIN OUTCOMES AND MEASURES Number of nevi labeled UDN and morphologically suspicious nevi, specificity of lesion-focused analysis and IPCA, and number of nevi identified for biopsy. RESULTSOf the 2089 clinical images of nevi from 80 patients (median number of nevi per patient, 26 [range, 8-81]) and 766 dermoscopic images (median number of nevi per patient, 19 [range, 8-81]), all melanomas were labeled UDN and as morphologically suspicious nevi by the 9 dermatologists. The median number of UDN detected per patient was 0.8 among the clinical images of nevi (mean, 1.0; range, 0.48-2.03) and 1.26 among the dermoscopic images (mean, 1.4; range, 1.00-2.06). The propensity to consider more or fewer nevi as having ugly duckling signs was independent of the presentation (clinical or dermoscopic). The agreement among the dermatologists regarding UDN was lower with dermoscopic images (mean pairwise agreement, 0.53 for clinical images and 0.50 for dermoscopic images). The specificity of IPCA was 0.96 for clinical images and 0.95 for dermoscopic images vs 0.88 and 0.85, respectively, for lesion-focused analysis. When both IPCA and lesion-focused analyses were used, the number of nevi considered for biopsy was reduced by a factor of 6.9 compared with lesion-focused analysis alone. CONCLUSIONS AND RELEVANCE Intrapatient comparative analysis is of major importance to the effectiveness of the diagnosis of melanoma. Introducing IPCA using the ugly duckling sign in computer-assisted diagnosis systems would be expected to improve performance.

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“…Hedera helix is a popular decorative plant that can cause dermatitis not only from its leaves but also from its roots (3). It is reported to have antimicrobial properties and is used therapeutically in a variety of ointments, hair lotions, teas and expectorants.…”

Section: Commentmentioning

confidence: 99%