J. Clin. Lab. Anal. volume 27, issue 6, P423-426 2013 DOI: 10.1002/jcla.21622 View full text
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Gaosi Xu, Yingqian Gong

Abstract: Background The aim of this study was to elucidate whether the CD4+ memory T (Tm) cells differentiation to regulatory T cells (Tregs) play a role in the immunological defects in patients with chronic kidney disease (CKD), and if the oxidized low‐density lipoprotein (oxLDL) had affect on on CD4+ Tm cells and Tregs apoptosis in these subjects. Methods CD4+ Tm cells and Tregs were detected by flow cytometry in each group of ten subjects. Apoptosis was measured by flow cytometry and confirmed by Western blotting. …

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