Depressive symptoms, social anxiety, and perceived neck function in patients with head and neck cancer

Rhoten, Bethany A.; Murphy, Barbara A.; Dietrich, Mary S.; Ridner, Sheila H.

doi:10.1002/hed.25129

Cited by 23 publications

(28 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In total 33 of these articles fulfilled the eligibility criteria. In addition, two studies were included after screening the reference lists, resulting in 35 articles . These 35 articles provided results on 27 separate studies.…”

Section: Resultsmentioning

confidence: 99%

“…In Table , the characteristics of the 35 included studies are described. Twenty‐one studies reported on factors associated with depression at a single time point, 10 studies on factors associated with the course of depression and four on both . Results on factors associated with depression at a single time point and the course of depression are presented separately.…”

Section: Resultsmentioning

confidence: 99%

“…Of the 14 studies that investigated factors associated with the course of depression, publication year ranged 1987 to 2018 . Studies mainly focused on mixed HNC patients; two studies focused on oral cavity or laryngeal cancer .…”

Section: Resultsmentioning

confidence: 99%

“…Studies mainly focused on mixed HNC patients; two studies focused on oral cavity or laryngeal cancer . Except for one study, which used a clinical diagnosis of depression, all studies measured symptoms of depression using the HADS‐D, CES‐D, BDI, or SCL‐90 …”

Section: Resultsmentioning

confidence: 99%

“…Eleven of the 35 studies were of high methodological quality (Appendix B). The majority of studies (23/35) did not have a baseline participation rate (the percentage of all eligible patients who wants to participate) of at least 80% or showed selective nonresponse (characteristics of participants differed from those patients who were not willing to participate) . Twenty‐one studies included less than 100 patients and about half (17/35) performed multivariate analyses …”

Section: Resultsmentioning

confidence: 99%

See 4 more Smart Citations

Factors associated with depression over time in head and neck cancer patients: A systematic review

et al. 2019

View full text Add to dashboard Cite

Objective To systematically review the literature on factors associated with a clinical diagnosis of depression or symptoms of depression (depression) among head and neck cancer (HNC) patients. Methods The search was conducted in PubMed, PsycINFO, and CINAHL. Studies were included if they investigated factors associated with depression among HNC patients, they were of prospective or longitudinal nature, and English full text was available. The search, data extraction, and quality assessment were performed by two authors. Based on the data extraction and quality assessment, the level of evidence was determined. Results In total, 35 studies were included: 21 on factors associated with depression at a single (later) time point, 10 on the course of depression, and four on both. In total, 77 sociodemographic, lifestyle, clinical, patient‐reported outcome measures, and inflammatory factors were extracted. Regarding depression at a single time point, there was strong evidence that depression at an earlier time point was significantly associated. For all other factors, evidence was inconclusive, although evidence suggests that age, marital status, education, ethnicity, hospital/region, sleep, smoking, alcohol, surgery, treatment, tumor location, and recurrence are not important associated factors. Regarding the course of depression, we found inconclusive evidence for all factors, although evidence suggests that gender, age, chemotherapy, pain, disease stage, treatment, and tumor location are not important associated factors. Conclusion Depression at an earlier time point is significantly associated with depression later on. Several sociodemographic and clinical factors seem not to be important factors associated with depression. For other factors, further research is warranted.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Factors associated with depression over time in head and neck cancer patients: A systematic review

et al. 2019

View full text Add to dashboard Cite

show abstract

Flourishing in head and neck cancer survivors

Harris

Atchison

et al. 2022

Cancer Medicine

View full text Add to dashboard Cite

Background There is a growing cohort of head and neck cancer (HNC) patients affected by late‐ and long‐term posttreatment side effects. Our study evaluates the relationship between the demographics, clinical characteristics, and posttreatment symptom burden with the subjective sense of flourishing among HNC survivors. Methods A cross‐sectional, single‐center study of adult survivors of squamous cell cancer of the oral cavity, oropharynx, and larynx/hypopharynx who completed the Secure Flourishing Index (SFI) and patient‐reported outcomes related to depression, anxiety, swallowing dysfunction, neck disability, and insomnia between November 2020 and April 2021. Results A total of 100, predominantly male (86%), survivors with an average age of 63.0 ± 9.6 were included in the study. Univariable analysis showed a significant association between higher flourishing scores and advanced age (95% CI: [0.011, 0.84], p = 0.0441), normal diet (95% CI: [5.79, 31.18], p = 0.0149), employment (95% CI: [1.24, 17.20], p = 0.0239), higher income (95% CI: [7.30, 27.72], p = 0.0248), and decreased reported difficulty paying for needs (95% CI: [−33.46, −18.88], p < 0.001). Flourishing was inversely associated with higher symptoms of depression (95% CI: [−2.23, −1.15], p < 0.001), anxiety (95% CI: [−1.92,‐0.86], p < 0.001), swallowing dysfunction (95% CI: [−0.77, −0.26], p < 0.001), neck disability (95% CI: [−1.05, −0.35], p < 0.001), and insomnia (95% CI: [−1.12, −0.22], p = 0.004) in the multivariable analysis. Conclusions Common late‐ and long‐term side effects of HNC treatment and financial hardship are associated with lower levels of flourishing or a more negative perception of life after treatment. Results highlight the importance of symptom burden for survivors' overall evaluation of their quality of life.

show abstract

Prognostic value of nutritional impairment on treatment‐related toxicity and survival in patients with nasopharyngeal carcinoma taking normal nutrition before radiotherapy

Lin

et al. 2020

Head & Neck

View full text Add to dashboard Cite

Background: To investigate nutritional impairment during intensitymodulated radiotherapy (IMRT) in patients with nasopharyngeal carcinoma (NPC) taking normal nutrition before IMRT and its effect on treatment-related toxicities (TRTs) and survival. Methods: Modified nutrition index (m-NI) of 187 patients with NPC, comprised eight indicators (body mass index, circumference of upper arm muscles, total lymphocyte count, red blood cell count, levels of albumin, pre-albumin, transferrin, and hemoglobin), were evaluated before/after IMRT. Patient characteristics, m-NI, and the follow-up data for survival and TRTs were analyzed. Results: The m-NI scores of patients with NPC decreased significantly after IMRT. Severe nutritional impairment (SNI; decrease in m-NI score ≥50%) was an independent prognostic factor for overall survival (OS) and an independent risk factor for grade ≥2 oral mucositis. Classification T4 disease and smoking were SNI risk factors. Conclusions: SNI during IMRT is a risk factor for oral mucositis and a prognostic factor for worse OS in patients with NPC.

show abstract

Depressive symptoms, social anxiety, and perceived neck function in patients with head and neck cancer

Abstract: Impaired physical function and psychological distress are intertwined for patients with head and neck cancer long after completing treatment.

Cited by 23 publications

References 23 publications

Factors associated with depression over time in head and neck cancer patients: A systematic review

Factors associated with depression over time in head and neck cancer patients: A systematic review

Flourishing in head and neck cancer survivors

Prognostic value of nutritional impairment on treatment‐related toxicity and survival in patients with nasopharyngeal carcinoma taking normal nutrition before radiotherapy

Contact Info

Product

Resources

About