Depression Symptoms in Haemodialysis Patients Predict All-Cause Mortality but Not Kidney Transplantation: A Cause-Specific Outcome Analysis

Chilcot, Joseph; Guirguis, Ayman; Friedli, Karin; Almond, Michael; Day, Clara; Silva-Gane, Maria Da; Davenport, Andrew; Fineberg, Naomi; Spencer, Benjamin T.; Wellsted, David; Farrington, Ken

doi:10.1007/s12160-017-9918-9

Cited by 43 publications

(34 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…But as with more recent studies, we were unable to confirm this association . As our patients with longer times to recover postdialysis also had higher self‐reported depression scores, and higher self‐reported depression scores are associated with increased risk of mortality . Then this may explain previous reports of an association between postdialysis recovery times and survival…”

Section: Discussioncontrasting

confidence: 79%

“…5,21 As our patients with longer times to recover postdialysis also had higher self-reported depression scores, and higher self-reported depression scores are associated with increased risk of mortality. 31 Then this may explain previous reports of an association between postdialysis recovery times and survival. 30 In our study, we found that patients who self-reported greater depression scores also reported longer postdialysis recovery times.…”

Section: Discussionmentioning

confidence: 64%

See 1 more Smart Citation

Postdialysis recovery time is extended in patients with greater self‐reported depression screening questionnaire scores

Davenport

Guirguis

Almond

et al. 2018

Hemodialysis International

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussioncontrasting

confidence: 79%

Section: Discussionmentioning

confidence: 64%

Postdialysis recovery time is extended in patients with greater self‐reported depression screening questionnaire scores

Davenport

Guirguis

Almond

et al. 2018

Hemodialysis International

Self Cite

View full text Add to dashboard Cite

show abstract

“…1,2 Although the absolute rates of clinically diagnosed depression are much lower, 3 self-reported depression is associated with increased over-all mortality. 4 A number of psychological theories, including human becoming theory, Bandura's self-efficacy theory, and Orem's self-care model, [5][6][7] have suggested that patients who take greater care of their own medical care have less depression and are more motivated to perform and promote activities designed to maintain or improve health care. 8 Indeed, studies in other chronic healthcare conditions, diabetes mellitus and congestive heart failure have reported that patients who take greater control of their own medical care [9][10][11][12] reported a reduction in emotional burden, 9 short-term improvement in glycaemic control, 10 over-all quality of life, 11 and shortterm changes in self-reported self-management skills predicted intermediate-term changes in improved mental quality of life and long-term changes in better physical quality of life.…”

Section: Introductionmentioning

confidence: 99%

The effects of supported shared‐care and hemodialysis self‐care on patient psychological well‐being, interdialytic weight gain, and blood pressure control

Maharjan

Davenport

2019

Hemodialysis International

Self Cite

View full text Add to dashboard Cite

Introduction: Traditionally hemodialysis (HD) treatments are undertaken by dialysis staff. Self-care has been reported to improve psychological well-being and treatment compliance for patients with chronic diseases. We evaluated our shared-care HD program to determine whether shared-care benefits patients.Methods: We reviewed the electronic health care and HD sessional records and psychological distress thermometer (DT) scores of patients in our HD centers. HD shared care was classified as grade 0-none, grade 1 patients weighing themselves and measuring blood pressure (BP), grade 2 performs HD, and grade 3 additionally troubleshoots problems.Findings: We reviewed 675 HD patients; mean age 64.1 AE 16.3 years, 62.3% male, 45.9% diabetic, Stoke-Davies co-morbidity grade 1 (1-1), frailty score 4 (3-5), DT 3 (0-5). 60.3% performed no shared care, 19% grade 1, 14.8% grade 2, and 6% grade 3. Patients performing more shared care were younger, less frail, less co-morbid, and physically stronger. We then propensity matched 113 patients with grade ≥ 2 shared care for age and frailty with 113 no shared-care patients. Fewer shared-care patients were prescribed antihypertensives (50.7 vs. 70.7%, P < 0.01), and had lower serum N terminal probrain natriuretic peptide 3033 (1083-8502) vs. 4814(1514-135821) pg/mL), phosphate (1.62 AE 0.49 vs. 1.78 AE 0.62 mmol/L), and higher albumin (40.7 AE 4.3 vs. 38.0 AE 4.3 g/ L), all P < 0.05 but no differences in psychological DT scores.Discussion: Although there was no significant benefit in psychological well-being, as measured by the self-reported DT, patients performing more shared care demonstrated other benefits in terms of blood pressure and volume control.

show abstract

“…There is a growing body of evidence demonstrating the association between depression and mortality among individuals with End‐Stage Kidney Failure (ESKF). It is estimated that the presence of depressive symptoms is associated with a 50% increase in the risk of mortality . This is particularly concerning given the high prevalence of depression, which is estimated to be approximately between 23%‐39%, depending on whether diagnostic or screening tools are used for evaluation .…”

Section: Introductionmentioning

confidence: 99%

Is successful treatment of depression in dialysis patients an achievable goal?

Chilcot

Hudson

2018

Seminars in Dialysis

Self Cite

View full text Add to dashboard Cite

Depression is undisputedly common among individuals with End‐Stage Kidney Failure and associated with adverse outcomes. It is well recognized that effective treatments for depression are needed within routine dialysis care. But, are we any closer to successfully treating depression in dialysis patients? We consider this question here with respect to two common treatments, antidepressant medication and cognitive behavioural therapy (CBT). Currently, there are limited data from randomized placebo‐controlled trials regarding the acceptability and efficacy of antidepressants. CBT trials appear to show more consistent treatment effects, albeit the feasibility of routine delivery remains unknown. No studies in dialysis patients has evaluated the combined effects of CBT with antidepressants. There is a need to consider pragmatic depression treatment trials in dialysis patients in order to increase study recruitment in order to have more reliable data from which to evaluate the evidence base. Furthermore, we need to understand why treatments work, and for whom do they work? Lastly, addressing issues surrounding treatment acceptability and implementation as part of regular care remain as key challenges that require attention if we are to improve the mental health of individuals on dialysis.

show abstract

Depression Symptoms in Haemodialysis Patients Predict All-Cause Mortality but Not Kidney Transplantation: A Cause-Specific Outcome Analysis

Abstract: (ISRCTN06146268).

Cited by 43 publications

References 37 publications

Postdialysis recovery time is extended in patients with greater self‐reported depression screening questionnaire scores

Postdialysis recovery time is extended in patients with greater self‐reported depression screening questionnaire scores

The effects of supported shared‐care and hemodialysis self‐care on patient psychological well‐being, interdialytic weight gain, and blood pressure control

Is successful treatment of depression in dialysis patients an achievable goal?

Contact Info

Product

Resources

About