Depression-related weight change and incident diabetes in a community sample

Abstract

This cohort study aimed to compare the incidence of type 2 diabetes in adults with depression-related weight gain, depression-related weight loss, depression with no weight change, and no depression. The study sample included 59,315 community-dwelling adults in Ontario, Canada. Depression-related weight change in the past 12 months was measured using the Composite International Diagnostic Interview—Short Form. Participants were followed for up to 20 years using administrative health data. Cox proportional hazards models compared the incidence of type 2 diabetes in adults with depression-related weight change and in adults with no depression. Adults with depression-related weight gain had an increased risk of type 2 diabetes compared to adults no depression (HR 1.70, 95% CI 1.32–2.20), adults with depression-related weight loss (HR 1.62, 95% CI 1.09–2.42), and adults with depression with no weight change (HR 1.39, 95% CI 1.03–1.86). Adults with depression with no weight change also had an increased risk of type 2 diabetes compared to those with no depression (HR 1.23, 95% CI 1.04–1.45). Associations were stronger among women and persisted after adjusting for attained overweight and obesity. Identifying symptoms of weight change in depression may aid in identifying adults at higher risk of type 2 diabetes and in developing tailored prevention strategies.

The relationship of within-individual and between-individual variation in mental health with bodyweight: An exploratory longitudinal study

“…The majority of research to date on the relationship between mental health and weight has been limited by a reliance on cross-sectional studies [2][3][4][5], and extant prospective studies are limited by infrequent measurements of mental health and weight, with periods of typically one to several years between measurements [6][7][8][9][10]. It is, therefore, unclear how small within-individual fluctuations in mental wellbeing predict weight over shorter time periods, e.g.…”

Social Support and Depression among Stroke Patients: A Topical Review

“…In addition to sad feelings and loss of interest, people with depression may typically experience somatic symptoms, including changes in appetite, sleeping disorder, chronic pain in joints, the back and limbs, fatigue, and gastrointestinal problems [11,12]. Changes in appetite and gastrointestinal problems may then result in other health problems such as diabetes [13]. Besides, depressive symptoms are associated with increased social isolation [14].…”

“…As introduced above, depression does not just impact mental health, but also introduces somatic symptoms and problems in daily life [11][12][13][14][15]25,26]. However, what makes depression worse is that 69% of patients who met the criteria of depression reported only somatic symptoms when they paid a visit to health professionals, according to a study by Simon et al [27].…”