Depression is associated with recurrent chest pain with or without coronary artery disease: A prospective cohort study in the emergency department

Kim, Yeunjung; Soffler, Morgan; Paradise, Summer; Jelani, Qurat‐ul‐ain; Dziura, James; Sinha, Rajita; Safdar, Basmah

doi:10.1016/j.ahj.2017.06.003

Cited by 28 publications

(27 citation statements)

References 22 publications

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“…Depression was negatively associated with HRQL in the ‘chest symptoms’ domain. This could reflect the high burden of the underlying ILD or could be due to the general association between chest pain and depression independent of ILD [ 32 ]. The lack of association between HRQL and other comorbidities could be due to the low number of patients for the distinct comorbidities.…”

Section: Discussionmentioning

confidence: 99%

Quality of life assessment in interstitial lung diseases:a comparison of the disease-specific K-BILD with the generic EQ-5D-5L

et al. 2018

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BackgroundPatients with interstitial lung diseases (ILD) have impaired health-related quality of life (HRQL). Little is known about the applicability of the disease-specific King’s Brief Interstitial Lung Disease questionnaire (K-BILD) and the generic EQ-5D-5L in a German setting.MethodsWe assessed disease-specific (K-BILD) and generic HRQL (EQ-5D experience based value set (EBVS) and Visual Analog Scale (VAS)) in 229 patients with different ILD subtypes in a longitudinal observational study (HILDA). Additionally, we assessed the correlation of the HRQL measures with lung function and comorbidities. In a linear regression model, we investigated predictors (including age, sex, ILD subtype, FVC percentage of predicted value (FVC%pred), DLCO percentage of predicted value, and comorbidities).ResultsAmong the 229 patients mean age was 63.2 (Standard deviation (SD): 12.9), 67.3% male, 24.0% had idiopathic pulmonary fibrosis, and 22.3% sarcoidosis. Means scores were as follows for EQ-5D EBVS 0.66(SD 0.17), VAS 61.4 (SD 19.1) and K-BILD Total 53.6 (SD 13.8). K-BILD had good construct validity (high correlation with EQ-5D EBVS (0.71)) and good internal consistency (Cronbach’s alpha 0.89). Moreover, all HRQL measures were highly accepted by patients including low missing items and there were no ceiling or floor effects. A higher FVC % pred was associated with higher HRQL in all measures meanwhile comorbidities had a negative influence on HRQL.ConclusionsK-BILD and EQ-5D had similar HRQL trends and were associated similarly to the same disease-related factors in Germany. Our data supports the use of K-BILD in clinical practice in Germany, since it captures disease specific effects of ILD. Additionally, the use of the EQ-5D-5L could provide comparison to different disease areas and give an overview about the position of ILD patients in comparison to general population.Electronic supplementary materialThe online version of this article (10.1186/s12931-018-0808-x) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Quality of life assessment in interstitial lung diseases:a comparison of the disease-specific K-BILD with the generic EQ-5D-5L

et al. 2018

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“…The results of this study indicated that depression experienced by CHD patients was in the mild category but with a high-frequency occurrence. These results provided an overview of the need for serious effort to prevent an increase in depression levels thus unexpected adverse outcomes can be avoided (Huffman et al, 2010;Kim et al, 2017;Lichtman et al, 2014).…”

Section: Discussionmentioning

confidence: 94%

Determinant Factors of Depression in Patients with Coronary Heart Disease

et al. 2019

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Background. Depression has been related to poor quality of life and recurrence in CHD patients. It is important to explore factors associated with the depression to prevent problems and to assist with appropriate intervention. Furthermore, the determinants of depression in CHD patients in Indonesia are still unknown. Purpose. This study aimed to identify the determinants of depression in CHD patients in Indonesia. Method. This study was a quantitative study with a cross-sectional approach. Samples were recruited from outpatient care in a referral hospital in Bandung using a consecutive sampling technique for a-2 month period (n=101). Data were collected using a questionnaire package consisting of a demographic questionnaire, Beck Depression Index [BDI] (II), Zung Self-rating Anxiety Scale, Seattle Angina Questionnaire, and Spirituality Index of Well-Being. Data were analyzed using descriptive quantitative and logistic regression analysis. Findings. In terms of its association with depression in CHD patients, low spiritual well-being had the highest odds ratio [OR] (OR = 9.3, 95% CI = 2.968 - 29.451, p <0.01); non-anxious state and medication history had low ORs (sequentially OR = 0.2, 95% CI = 0.067 - 0.644, p < 0.01; OR=0.2 95% CI = 0.062 - 0.772, p < 0.01); PCI (percutaneous coronary intervention) with medication had the lowest OR value (OR = 0.02, 95% CI = 0.002 - 0.278, p <0.01). On the other hand, unmarried status and male gender were identified as confounding variables. Conclusions. Low spiritual well-being was a major predictor of depression in CHD patients, whereas no anxiety, and history of medication, consist of CHD medication and reperfusion therapy contributed to a lower risk of depression. It is recommended to include strategies in improving spiritual well being and managing anxiety to reduce the risk of depression among CHD patients.

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“…Our results suggest that the healthcare burden and costs are substantial, due to repeated general practitioner visits, the possible additional diagnostic tests that are performed and the economic burden, given that the majority of this population is still at working age. In the WISE study the costs of symptom-driven care in women with persistent angina was reported to be almost 750.000 dollars per year ( 10 ). Even though healthcare costs cannot be compared between countries, it does provide insight in the extensive costs that are associated with symptomatic women and men with non-obstructed coronary arteries.…”

Section: Discussionmentioning

confidence: 99%

“…Prior studies on the outcome of these women were mainly investigating major adverse cardiovascular events as registered in the hospital setting ( 9 , 10 ). In the Women's Ischemia Syndrome Evaluation (WISE) study, over 15% of women with non-obstructed coronary arteries underwent a second coronary angiography during 5 years of follow up ( 11 ).…”

Section: Introductionmentioning

confidence: 99%

Persistent Symptoms and Health Needs of Women and Men With Non-Obstructed Coronary Arteries in the Years Following Coronary Angiography

Groepenhoff

Eikendal

Rittersma

et al. 2021

Front. Cardiovasc. Med.

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Background: The prognosis of women and men with persistent anginal complaints and non-obstructed coronary arteries is impaired as compared with asymptomatic women and men. The increased healthcare burden in the hospital due to repeated coronary angiography in these women and men has been documented, yet little is known about the percentage of women and men who remain symptomatic and under care of the general practitioner in the years following a coronary angiographic outcome of non-obstructed coronary arteries.Methods: From the Utrecht Coronary Biobank study, including individuals who underwent a coronary angiography from 2011 to 2015 (N = 2,546, 27% women), we selected women and men with non-obstructed coronary arteries (N = 687, 39% women). This population was linked to the Julius General Practitioners Network (JGPN); a database with routine care data of general practitioners. For every individual with non-obstructed coronary arteries, we selected an asymptomatic non-referred age-, sex-, and general practitioner-matched individual from the JGPN. We compared the healthcare consumption of men and women with non-obstructed coronary arteries to these matched individuals. The McNemar's test was used for pairwise comparison, and sex differences were assessed using stratified analyses.Results: The prevalence of non-obstructed coronary arteries was higher in women as compared with men (39 vs. 23%). During a median follow-up of 7 years [IQR 6.4–8.0], 89% of the individuals with non-obstructed coronary arteries (91% women and 87% men) visited their general practitioner for one or more cardiovascular consultations. This was compared to 34% of the matched individuals (89 vs. 34%, p < 0.001). The consultations were most often for angina (equivalents) (57 vs. 11%, p < 0.001) and heart failure (10 vs. 2%, p = 0.015). In addition, they more often consulted the general practitioner for psychosocial complaints (31 vs. 15%, p = 0.005). Findings were similar for women and men.Conclusions: A coronary angiographic outcome of non-obstructed coronary arteries is more common in women than in men. In the years following the coronary angiography, the majority of the population remains symptomatic. Both women and men with non-obstructed coronary arteries had higher health needs for angina, heart failure, and psychosocial complaints than matched asymptomatic individuals.

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Depression is associated with recurrent chest pain with or without coronary artery disease: A prospective cohort study in the emergency department

Cited by 28 publications

References 22 publications

Quality of life assessment in interstitial lung diseases:a comparison of the disease-specific K-BILD with the generic EQ-5D-5L

Quality of life assessment in interstitial lung diseases:a comparison of the disease-specific K-BILD with the generic EQ-5D-5L

Determinant Factors of Depression in Patients with Coronary Heart Disease

Persistent Symptoms and Health Needs of Women and Men With Non-Obstructed Coronary Arteries in the Years Following Coronary Angiography

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