2006
DOI: 10.1007/s00125-006-0159-x
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Abstract: Aims/hypothesis: Evidence strongly suggests that depression and type 2 diabetes are associated, but the direction of the association is still unclear. Depression may occur as a consequence of having diabetes, but may also be a risk factor for the onset of type 2 diabetes. This study examined the latter association by reviewing the literature and conducting a meta-analysis of longitudinal studies on this topic. Methods: Medline and PsycInfo were searched for articles published up to January 2005. All studies th… Show more

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Cited by 828 publications
(563 citation statements)
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“…However, a recent metaanalysis of nine prospective studies reported that depressed adults have a 37% increased risk of developing type 2 diabetes [45]. Negative life events during the first 2 years of life, such as divorce, high parenting stress and foreign origin of the mother predicted an increased risk of diabetesrelated autoimmunity, which critically contributes to the development of type 1 diabetes [46,47].…”
Section: Discussionmentioning
confidence: 99%
“…However, a recent metaanalysis of nine prospective studies reported that depressed adults have a 37% increased risk of developing type 2 diabetes [45]. Negative life events during the first 2 years of life, such as divorce, high parenting stress and foreign origin of the mother predicted an increased risk of diabetesrelated autoimmunity, which critically contributes to the development of type 1 diabetes [46,47].…”
Section: Discussionmentioning
confidence: 99%
“…Although major depression may not be a clearly defined entity, depressive symptoms have been found to be associated with type 2 diabetes in a bidirectional manner. A meta-analysis of nine trials concluded that depressed adults have a 37% higher risk of developing type 2 diabetes [3]. Furthermore, adults with diabetes exhibit a higher risk of depression [76], as do children with metabolic syndrome [77].…”
Section: Psychosocial Factorsmentioning
confidence: 99%
“…less muscle work-all factors promoting obesity. Psychosocial factors may also have contributed to the steep increase in the prevalence type 2 diabetes, in particular increases in the prevalence of short duration of sleep and depressive mood [2,3]. A general diabetes risk factor with increasing prevalence is age.…”
Section: Introductionmentioning
confidence: 99%
“…A pooled analysis of nine longitudinal studies showed a 1.4-fold increased risk of diabetes in depressed patients [2]. Two subsequently published longitudinal studies confirmed a significantly increased risk of onset of type two diabetes in depressed patients [3,4], whereas two other studies did not find an increased risk of diabetes in individuals older than 50 years [5] or in antidepressant users [6].…”
Section: Introductionmentioning
confidence: 99%