Depression and anxiety in patients of chronic kidney disease undergoing haemodialysis: A study from western Rajasthan

Gadia, Pankaj; Awasthi, Ankit; Jain, Sanjay; Koolwal, Ghanshyam Das

doi:10.4103/jfmpc.jfmpc_840_20

Cited by 22 publications

(21 citation statements)

References 20 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous studies have shown that gender, educational level [1], serum creatinine concentration [6], and duration of HD [7], are associated with depressive symptoms in patients receiving HD. The illiterate patients had more depressive symptoms [4,5].…”

Section: Introductionmentioning

confidence: 99%

Hierarchical multiple regression investigating factors associated with depressive symptoms in the middle-aged and elderly undergoing haemodialysis

Chang

Bai²,

Lai³

et al. 2023

BMC Public Health

View full text Add to dashboard Cite

Background Depressive moods are commonly seen in patients who receive haemodialysis. This can cause a lack of compliance in their treatment procedures and increase the rate of hospitalization. This study aimed to investigate the relationship between social support and degree of depression in middle-aged and elderly patients undergoing haemodialysis and the predictors of depressive symptoms. Methods A cross-sectional correlational study was designed with a structured questionnaire survey. Patients over 40 years of age were included from five haemodialysis centres. Measures embraced a demographic and clinical characteristics questionnaire, the Centre for Epidemiologic Studies Depression Scale, and the Personal Resource Questionnaire 2000. Statistical analysis was performed using hierarchical multiple regression analysis. Results A total of 179 patients over 40 years of age were included from five haemodialysis centres in the analysis. The mean CES-D score was 19.0(12.3); the majority of participants (60.3%) had a CES-D score ≥ 15, indicating likely depressive status. The mean PRQ2000 score was 75.7(15.9). The proportional mean of the PRQ2000 was 72.11%, indicating moderate social support for participants in this study. Data disclosed that marital status, number of comorbidities, exercise behaviour, and social support could significantly predict depressive symptoms; total explanatory variance was 31.3%. Conclusion Health care professionals should identify those at high risk of depressive symptoms when they provide care to the middle-aged and elderly patients undergoing haemodialysis. These findings may lead to greater insights into the nursing and rehabilitative care of patients treated by chronic maintenance haemodialysis.

show abstract

Section: Introductionmentioning

confidence: 99%

Hierarchical multiple regression investigating factors associated with depressive symptoms in the middle-aged and elderly undergoing haemodialysis

Chang

Bai²,

Lai³

et al. 2023

BMC Public Health

View full text Add to dashboard Cite

show abstract

“…Participants (3 studies) from AFR [30,58,70]; 4,295 (14 studies) from EUR [31,33,34,36,39,43,56,61,66,68,75,78,80,82]; 3,962 (17 studies) from AMR [22,23,24,25,26,29,32,35,38,45,53,55,62,65,67,69,77]; 679 (7 studies) from EMR [40,49,51,60,64,74,81]; 846 (7 studies) from SEAR [28,47,50,59,71,73,79], and 69,660 (13 studies) from the WPR. [27,37,41,42,44,46,48,52,54,57,63,72,76] Figure 2 shows the geographical distribution of the continents of the included studies.…”

Section: Resultsmentioning

confidence: 99%

“…The clinical diagnostic criteria included those of the DSM (20 studies, 2,028 participants) [23,26,27,28,32,34,35,42,46,49,56,60,66,67,70,72,73,74,76,78] ICD (5 studies, 69,954 participants) [25,37,47,71,79] SCID (15 studies, 1,435 participants)[22,33,39,40,43,48,51,53,54,56,57,59,61,65,82], and MINI (21 studies, 6,274 participants). [24,29,30,31,36,38,41,44,45,50,52,55,58,62,64,68,69,75,77,80,81] The sample size of the component studies ranged from 20 [70] to 67,866 [37] patients, with the proportion of women ranging from 0% [25] to 68% [74].…”

Section: Resultsmentioning

confidence: 99%

Global Prevalence of Depression in Chronic Kidney Disease: A Systematic Review and Meta-Analysis

Adejumo,

Edeki,

Dapo

et al. 2023

Preprint

View full text Add to dashboard Cite

BackgroundChronic kidney disease (CKD) is commonly associated with psychosocial problems, especially depression, contributing to poor overall outcomes in CKD patients. Depression has not been given adequate priority in the management of CKD despite its significant adverse impact.ObjectivesThis systematic review and meta-analysis determined the pooled prevalence of clinical depression in the global CKD population and sub-populations.DesignA systematic search of PubMed, African Journals Online (AJOL), and EMBASE was undertaken to identify published articles with relevant data between 1989 and 2022. The pooled prevalence of clinical depression in the global CKD population was determined using random effects meta-analytic techniques.ParticipantsGlobal adult and paediatric CKD populationResultsEligible Sixty-one articles were included in this review, comprising 79,691 CKD patients from 26 countries. The participants’ mean age ranged from 11.0 to 76.3 years. Most (68.9%) of the studies had medium methodological quality. The overall pooled prevalence of depression was 27.6% (95% CI: 23.9–31.5%). Studies using Diagnostic Statistical Manual (DSM), International Classification of Disease, Mini-International Neuropsychiatric Interview and Structured Clinical Interview for DSM disorder returned a pooled prevalence of 31.7%, 39.6%, 23.3%, 25.1%, respectively; p=0.09. There was significant difference in the pooled prevalence of CKD across the various continents; p=0.01.The prevalence of depression was higher among patients on chronic haemodialysis compared to those in pre-dialysis (31.1% versus 18.9%; p=0.02), and among those on hemodialysis compared to peritoneal dialysis (31.9% versus 20.4%; p=0.03). There was no significant difference between adults and children (28.0% versus 15.9%, p=0.17).ConclusionDepression is a common disorder in patients with CKD. The findings of this study have brought to the fore the need for clinicians to make deliberate efforts to evaluate CKD patients for depression, especially those with advanced stages of the disease.The study protocol was registered with PROSPERO (CRD42022382708)Strengths and LimitationsThe pooled prevalence of depression in this study correctly represents the magnitude of the depression in the CKD population because it included only studies where depression was diagnosed clinically.This review involved the global population of both adult and paediatric patients with pre-dialysis and dialytic kidney disease.Only a few studies in this review determined the prevalence of depression in the early stages of CKD.Studies reporting depression prevalence among kidney transplant patients were not included in this review, and the number of studies in the paediatric population was limited.

show abstract

“…Studies from Asia reported higher frequencies of depression in patients with ESRD in urban than in rural areas [24]. Low income [43], unemployment [2] and low education levels [29] are risk factors for depression of CKD or dialysis patients. However, in the reportings of prevalence of depression, adjustment of socioeconomic factors is usually not made.…”

Section: Related Risk Factorsmentioning

confidence: 99%

“…Family support can partially reduce patients’ psychological pressure and enhance physical QOL; appraisal support mediates the relationship between sleep disturbances and depressive symptoms [34]. However, family burdens related to a spouse [43] and number of children [29] are also risk factors for depression.…”

Section: Related Risk Factorsmentioning

confidence: 99%

Depression in dialysis

Tian

Chen

2021

Current Opinion in Nephrology &Amp; Hypertension

View full text Add to dashboard Cite

Purpose of review The aim of this study was to examine updated prevalence rates, risk factors and the prognosis, diagnosis and treatments for depression among dialysis patients. Recent findings Depression influences prognosis, complications, quality of life (QOL), treatment and costs for dialysis patients worldwide. Reported prevalence of depression is 13.1–76.3%; it is higher for dialysis than transplant and higher post than predialysis. Reported depression rates with peritoneal dialysis (PD) compared with in-centre haemodialysis (HD) are inconsistent. Related medical factors are known, but suspected associated patient characteristics including gender and race remain unexplored. Associations between depression in dialysis and QOL, mortality, pathophysiological mechanisms of increased mortality, infection and pathways of inflammation-mediated and psychosocial factors require clarification. Several depression screening instruments are validated for dialysis patients – the Structured Clinical Interview for DSM disorders (SCID) remains the gold standard – but authors suggest the diagnostic standard should be higher than for the general population. Short-term studies indicate nonpharmacological therapy achieves clinical effects for depression in dialysis patients, but research on long-term effects is needed. Summary Depression management through early screening and continuous care models emphasizing dynamic relationships between healthcare teams, patients and families should be encouraged. Large-scale studies of short-term and long-term benefits of pharmacological and nonpharmacological depression management are warranted.

show abstract

Depression and anxiety in patients of chronic kidney disease undergoing haemodialysis: A study from western Rajasthan

Cited by 22 publications

References 20 publications

Hierarchical multiple regression investigating factors associated with depressive symptoms in the middle-aged and elderly undergoing haemodialysis

Hierarchical multiple regression investigating factors associated with depressive symptoms in the middle-aged and elderly undergoing haemodialysis

Global Prevalence of Depression in Chronic Kidney Disease: A Systematic Review and Meta-Analysis

Depression in dialysis

Contact Info

Product

Resources

About