volume 66, issue 8, P5013-5017 1992
DOI: 10.1128/jvi.66.8.5013-5017.1992
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Abstract: Bacteriophage +6 has a segmented genome consisting of three pieces of double-stranded RNA (dsRNA). The viral procapsid is the structure that packages plus strands, synthesizes the complementary negative strands to form dsRNA, and then transcribes dsRNA to form plus-strand message. The minus-strand synthesis of a particular genomic segment is dependent on prior packagng of the other segments. The S' end of the plus strand is necessary and sufficient for packaging, while the normal 3' end is necessary for synthe…

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