Denture stomatitis and salivary Candida in Brazilian edentulous patients

Abstract

Denture stomatitis (DS) is frequently associated with high levels of Candida in saliva and deficient denture hygiene. In order to analyse the incidence of DS and its pre-disposing factors, we evaluated 77 edentulous patients before and 6 months after the placement of new complete dentures. Denture stomatitis was observed in 50.6 and 18.2% of the patients at the first and second evaluation, respectively. Salivary flow, Candida counts in saliva and Candida species were similar in both evaluations. Denture stomatitis and Candida in saliva were more common in females. Our results showed that denture replacement and denture hygiene improvement were useful for DS resolution, particularly types I and II. However, oral and denture hygiene must be continuous, inasmuch as salivary Candida counts remained high and it is considered an important pre-disposing factor for DS.

Effect of wearing complete dental prosthesis on candidal count

“…Mucosal lesions occurred more frequently in complete denture wearers followed by partial denture wearers. 12,19 The significant results of this study emphasize the critical need to measure candidal activity of complete denture wearers. 20 …”

“…This may be explained due to the fact that women have more candidal load on the basis of iron deficiency anemia and hormonal changes. [12][13][14] The majority of the women in the present study were in an age group where menopause was likely to occur. Most of the studies found that higher denture induced stomatitis in male patients in comparision to female.…”

Palatal Health of Those Wearing Complete Dentures: For How Long Must a Tissue Conditioner and Chlorhexidine Gluconate Mouthrinse be Used?

“…It usually affects the hard palate and occasionally causes angular cheilitis (2,6,11). Bright erythematous areas, frequently seen on the maxilla, have been found on the oral mucosa under complete or partial dentures in both jaws; they are frequently seen on the maxillae.…”

Detecção da expressão dos genes HWP1, ALS1 e ALS3 de C.albicans, por meio de RT-PCR em tempo real, após desinfecção química e por microonda, de resina acrílica para confecção de dentaduras

“…Embora estudos correntes indiquem que a EP esteja geralmente associada com a presença do fungo C. albicans na saliva, na mucosa bucal e/ou na superfície interna da prótese removível WALKER, 1987;BARBEAU et al, 2003;CAMPOS et al, 2008;CUMMING et al, 1990;DAR-ODEH;SHEHABI, 2003;EMAMI et al, 2007;FARAH;ASHMAN;CHALLACOMBE, 2000;FIGUEIRAL et al, 2007;IACOPINO;WATHEN, 1992;KULAK;ARIKAN;KAZAZOGLU, 1997;PIRES et al, 2002;RAMAGE et al, 2004;WEBB et al, 1998;WILSON, 1998;ZISSIS;YANNIKAKIS;HARRISON, 2006), outros fatores também podem predispor seu desenvolvimento como os relacionados ao uso da prótese, à microbiota e às condições sistêmicas do hospedeiro.…”

“…A ausência de higiene bucal e da prótese promove um ambiente favorável à proliferação de microrganismos, principalmente entre a mucosa de suporte e a própria superfície da prótese (FIGUEIRAL et al, 2007). Destaca-se que outros microrganismos como, por exemplo, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei, C. pseudotropicalis, C. dubliniensis e C. guilliermondi também podem colaborar para a patogênese da doença, no entanto, o fungo C. albicans é o mais freqüentemente associado (ARENDORF; WALKER, 1987;BARBEAU et al, 2003;DAR-ODEH;SHEHABI, 2003;EMAMI et al, 2007;FARAH;ASHMAN;CHALLACOMBE, 2000;FIGUEIRAL et al, 2007;FREITAS et al, 2008;IACOPINO;WATHEN, 1992;PIRES et al, 2002;RAMAGE et al, 2004;WILSON, 1998;ZISSIS;YANNIKAKIS;HARRISON, 2006 WALKER, 1987;BARBEAU et al, 2003;DAR-ODEH;SHEHABI, 2003;EMAMI et al, 2007;FARAH;ASHMAN;CHALLACOMBE, 2000;FIGUEIRAL et al, 2007;FREITAS et al, 2008;IACOPINO;WATHEN, 1992;PIRES et al, 2002;RAMAGE et al, 2004;WILSON, 1998;ZISSIS;YANNIKAKIS;HARRISON, 2006). …”