Dental anomalies in non‐syndromic orofacial clefts: A clinical approach

Neves, Lucimara Teixeira das; Carvalho, Izabel Maria Marchi de; Cobourne, Martyn T.; Gomide, Márcia Ribeiro

doi:10.1111/odi.14226

Cited by 5 publications

(4 citation statements)

References 160 publications

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“…Thus, it is possible that disorders in these events may predispose to dental anomalies in individuals with cleft . 29,30 Studies with two and three-dimensional images have identified mandibular asymmetry in patients with unilateral cleft lip and palate 31,32 Changes in mandibular volume were also observed in this type of cleft. 33 Further studies are necessary to relate mandibular changes and dental anomalies, especially root dilaceration in individuals with cleft.…”

Section: Discussionmentioning

confidence: 99%

Root Curvature in Non-Syndromic Oral Clefts: A Case-Control Study in a Brazilian Population

Lopes

Guimarães

Nascimento

et al. 2022

The Cleft Palate Craniofacial Journal

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Objective This study assesses the degree of root curvature in patients with non-syndromic cleft lip and/or palate (NSCL/P). Design Retrospective. Case-control study. Setting Root curvature was assessed in lower premolars and molars in 800 panoramic radiographs: 400 from patients with cleft and 400 from healthy control individuals. Root curvature was classified according to its angulation, as well as its apical, medial, or coronal localization. Results The frequency of mild curvature in the NSCL/P group compared to the control group was higher in premolars especially in the left second premolar in cleft palate (OR: 6.91; 95% CI: 3.23−14.77; P < .0001). The frequency of moderate curvature in molars was significantly higher in the cleft group, with the highest risk in the right first molar in the cleft lip group (OR: 2.74; 95% CI: 1.67−4.52; P < .0001). Inclination was more frequently observed in the apical third of the root in the group with cleft, whereas for the control group, the curvature was more frequent in the medial third. In patients with cleft, the OR of curvature in the apical third was significant in premolars (left lower second premolar: Cleft lip, OR: 1.91; 95% CI: 1.04−3.52; P = .03; right lower second premolar: Cleft lip, OR: 1.91, 95% CI: 1.04−3.50; P = .03, cleft lip and palate, OR: 1.75; 95% CI: 1.12−2.73; P = .01). Conclusion The results of the current study indicate differences in root curvature in patients with non-syndromic cleft lip and/or palate, which should be considered during the dental treatment planning of patients.

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Section: Discussionmentioning

confidence: 99%

Root Curvature in Non-Syndromic Oral Clefts: A Case-Control Study in a Brazilian Population

Lopes

Guimarães

Nascimento

et al. 2022

The Cleft Palate Craniofacial Journal

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“…In addition, dens invaginatus such as radicular lingual groove always found in maxillary lateral incisor has higher prevalence in patients with CLP ( 37 ), it creates a pathological dental pocket. Such a pocket resulted from an infolding of the enamel into dentine destroys the connection between periodontal tissue and cementum and allows bacteria propagate within, which can't be easily removed ( 26 , 61 , 62 ).…”

Section: Mechanisms Linking Periodontitis and Clpmentioning

confidence: 99%

Dental caries and periodontitis risk factors in cleft lip and palate patients

Li²,

Zhang³

et al. 2023

Front. Pediatr.

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Cleft lip and palate (CLP) is the most common congenital facial malformation and has a significant developmental, physical, and psychological impact on those with the deformity and their families. Risk factors contributing to CLP may conclude as genetic factors and environmental factors. The anatomical and morphological abnormalities related to CLP are favorable for dental plaque accumulation on the tooth surface. Therefore, patients with CLP undergo poorer oral hygiene and higher susceptibility to dental caries and periodontitis. In this review, we aim to conclude and update probable causes underlying the association between CLP and poor oral health and provide novel ideas of targeted early prevention for such oral diseases.

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“…In favor of this connection are the epidemiological studies that show a higher frequency of dental anomalies in NSOC patients and unaffected relatives, and the genetic studies that show similarly altered genes and pathways in NSOC and dental anomalies. The connection between dental anomalies and NSOC is reviewed by das Neves et al, 2022. Initially, the authors report the frequencies of the most common dental anomalies in patients with NSOC and describe the candidate genes shared by these conditions.…”

Section: Figurementioning

confidence: 99%