Demodex folliculorum in rosacea

Fractionated ablative carbon dioxide laser for the treatment of rhinophyma

“…The first descriptions of this condition date back to the Middle Ages, but it was not clinically defined until 1845 when Hebra derived the term rhinophyma from the Greek words rhis , meaning nose, and phyma , meaning growth . Factors implicated in the worsening of rosacea and ultimately in the formation of rhinophyma have included Demodex folliculorum, alcohol, caffeine, spicy foods, and other vasodilatory agents . Androgenic influences have been implicated, as the incidence is greatly increased in males .…”

Refractory Demodex Folliculitis in Five Children with Acute Lymphoblastic Leukemia

“…There is controversy regarding the pathogenicity of the Demodex mite. Rosacea‐like demodicidosis was initially reported in adults with rosacea accompanied by proliferative numbers of D. folliculorum that resolved with a sulfur‐based “Danish ointment” (6–9). Increased numbers of Demodex mites have been found on the forehead and cheeks in patients with rosacea and pustular rosacea, when compared to healthy control population (10,11).…”

Demodex and eye disease

“…26,81,[84][85][86][87] Demodicosis in skin lesions, especially the face, is well documented in dermatology. [88][89][90][91] It is well established that a strong correlation exists between acne rosacea and Demodex, whereby a seven-to eight-fold increased risk of having Demodex in acne rosacea patients exists. 92 As D. brevis resides in sebaceous glands, it can be found in many areas of the body including the face, particularly the cheek and nasal-labial folds 10 as well as the meibomian glands of the eyelid, establishing a strong correlation between acne rosacea and MGD.…”