“…Flaps with no or very mild inflammatory infiltrate usually maintain clinical and histological skin features [4,7,10]. However, some histologic changes are still present such as reduced thickness of horny layer [7,9,10], orthokeratosis [11], mild acanthosis [11], normal or reduced number of skin appendages [2,7,9,10], decrease of secretory activity of sweat glands [9], basal keratinocyte pigmentation [9,10] and elastosis with thicker, tortuous and randomly oriented elastic fibers [8,10]. In this study, maintenance of skin histological features in flap specimens with no or mild inflammation was confirmed.…”