Definition of Three Serotypes of Hantaviruses by a Double Sandwich ELISA with Biotin-Avidin Amplification System

Four Serotypes of Haemorrhagic Fever with Renal Syndrome Viruses Identified by Polyclonal and Monoclonal Antibodies

“…So far, several investigators have proposed that hantavirus isolates can be classified into three (Schmaljohn et al, 1985;Goldgaber et al, 1985) or four (Lee et al, 1985b) serotypes. In the present study, 20 HFRS strains were analysed; the conclusions and proposed antigenic classification are shown in Table 6.…”

“…The serological relationships of HFRS viruses in the U.S.S.R. have also been reported (Tkachenko et al, 1982). Studies on the serotyping of HFRS viruses have been reported by Goldgaber et al (1985) and Lee et al (1985 b). We have developed an immune adherence haemagglutination (IAHA) test for the detection of HFRS virus antigen and antibody (Sugiyama et al, 1984b), and demonstrated that it discriminates Rattus virus strains from the Apodemus strain 76-118 (Sugiyama et al, 1984a).…”

Viruses of Hemorrhagic Fever with Renal Syndrome (HFRS) Grouped by Immunoprecipitation and Hemagglutination Inhibition

“…HFRS-related viruses have also been classi fied into 3 groups by enzyme-linked immun osorbent assay [13] and 4 groups by antibody test neutralization [14,15]. The relationships between virological differences among HFRS viruses and differences in clinical symptoms remain to be defined.…”

The antigenic analysis of haemorrhagic fever with renal syndrome viruses in China by monoclonal antibodies

“…The antigenic difference between those from wild species of mouse and most house rats was shown by using cross-IFAT, cross-neutralization and crossblocking tests (Song et al 1984). This has also been clearly shown by Schmaljohn et al (1985) and Goldgaber et al (1985). They defined three antigenic groups or serotypes by analysing the cross-reactivity of virus isolates in radio-and immunoassays.…”