2020
DOI: 10.5935/2595-0118.20200191
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Definition of pain revised after four decades

Abstract: BACKGROUND AND OBJECTIVES: Inflammation is a defense response of the body to a cellular damage caused by physical, chemical or biological agents, which triggers, among other factors, pain. Although inflammation plays an important role in the protection and regeneration of tissue injury, inflammatory pain results in decreased quality of life. In view of this, the development of safe and less invasive forms for the treatment of inflammatory pain is of great importance. The objective of this study was to evaluate… Show more

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Cited by 20 publications
(13 citation statements)
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References 11 publications
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“…Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, and it is described in terms of such damage directly associated with different functions of the neurological signal with nociceptive perception due to sensations stimulated by subjective and objective factors of the system [ 53 , 54 ]. In this sense, Okuyama et al [ 55 ] evaluated the usnic acid isolated from Usnea diffracta as an analgesic component in a murine pain model by the method of abdominal contortions induced by the intraperitoneal administration of acetic acid at concentrations of 30 and 100 mg/kg.…”
Section: Antinociceptive Activity and Cytotoxicity On Peripheral Blood Cellsmentioning
confidence: 99%
“…Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, and it is described in terms of such damage directly associated with different functions of the neurological signal with nociceptive perception due to sensations stimulated by subjective and objective factors of the system [ 53 , 54 ]. In this sense, Okuyama et al [ 55 ] evaluated the usnic acid isolated from Usnea diffracta as an analgesic component in a murine pain model by the method of abdominal contortions induced by the intraperitoneal administration of acetic acid at concentrations of 30 and 100 mg/kg.…”
Section: Antinociceptive Activity and Cytotoxicity On Peripheral Blood Cellsmentioning
confidence: 99%
“…The experience of pain is subjective and affects quality of life negatively. According to the Brazilian Society for the Study of Pain (Sociedade Brasileira para Estudo da Dor), the perception of pain varies from one individual to another and is influenced by culture and previous experience (14) .…”
Section: Discussionmentioning
confidence: 99%
“…Este estudo se propôs em realizar uma revisão integrativa baseada na leitura de artigos científicos internacionais acerca dos efeitos da FBM por LBI e/ou LED sobre a dor e incapacidade funcional em indivíduos com DLC. Segundo a Associação Internacional para Estudos da Dor (IASP), a dor pode ser definida como "uma experiência sensitiva e emocional desagradável associada a uma lesão tecidual real ou potencial, ou descrita nos termos de tal lesão" 27 . A DLC é uma condição altamente prevalente em todo o mundo e a principal causa de incapacidade em seus portadores, devido ainda os tratamentos não estarem bem estabelecidos pela literatura, optou-se em realizar o estudo envolvendo os efeitos da FBM por LBI 28 .…”
Section: Discussionunclassified