Defining the Susceptibility of Acne-Prone and Sensitive Skin Populations to Extrinsic Factors

Mills, Otto H.; Berger, Richard S.

doi:10.1016/s0733-8635(18)30437-6

Cited by 35 publications

(18 citation statements)

References 17 publications

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“…Born out of clinical practice, it might be that sensitive skin plays a role in interindividual variability in reactivity potential among dermatological patients, as experienced in skin diseases such as psoriasis or acne [6,63]. This knowledge relates sensitive skin to knowledge on pathology in skin diseases and could be the basis for addressing solutions to differences in individual skin reactions in clinical practice.…”

Section: Discussionmentioning

confidence: 99%

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What Is Sensitive Skin? A Systematic Literature Review of Objective Measurements

Richters

Falcone

Uzunbajakava³

et al. 2014

Skin Pharmacol Physiol

148

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Despite sensitive skin being highly prevalent, no consensus on the definition and pathomechanism of sensitive skin exists. Here we report the results of a systematic literature review of diagnostic methods for sensitive skin at clinical, histological and biophysical levels. A systematic search revealed 27 out of 1,701 articles which we appraised in detail. Impaired skin barrier function and increased vascular reactivity are most often associated with sensitive skin. We identified key reasons causing an ambiguity around the sensitive skin phenomenon. We propose using standardized selection methods of subjects by a multifactorial questionnaire spanning a range of provocations, including those of chemical, mechanical and environmental origin, followed by clinical, histological and top-notch biophysical measurements. This could lead to a breakthrough in the understanding of the sensitive skin phenomenon, fueling advances of biomedical and dermatological science. © 2014 S. Karger AG, Basel

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Section: Discussionmentioning

confidence: 99%

“…Various imprecisely defined terms have been proposed to characterize susceptible skin, emphasizing its heterogeneous presentation, and only few research groups have focused on objective approaches to identify differences in sensitive skin [1,2,3,4,5,6,7,8,9,10]. …”

Section: Introductionmentioning

confidence: 99%

What Is Sensitive Skin? A Systematic Literature Review of Objective Measurements

Richters

Falcone

Uzunbajakava³

et al. 2014

Skin Pharmacol Physiol

148

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“…Essentially a self‐diagnosed condition, the level and nature of symptoms needed to produce the self‐perception of sensitivity are difficult to quantify, but will almost certainly be highly variable between individuals. In 1991, Mills and Berger 4 attempted to categorize sensitive skin phenotypes, but acknowledged that, at present, we have little understanding as to why some people appear to have sensitive skin and/or react adversely to cosmetics, while others do not. Certainly, some pre‐existing skin conditions do appear to predispose to sensitive skin, atopic eczema being arguably the best known 3,4 …”

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confidence: 99%

Sensitive skin: an epidemiological study

et al. 2001

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“…Even though this test is quite artificial, it appears to correlate well with those individuals who experience heightened neurosensory input during actual cosmetic and skin care product use (13,14), but this remains controversial (15). Mills and Berger (16) have suggested selecting sensitive skin panelists based on the flushing response to red wine, history of a severe sunburn or allergic contact dermatitis, demonstration of a low minimal erythemal dose (MED), a high density of facial Demodex folliculorum mites, or heightened erythema due to friction following polyethylene‐film occlusion to the chin overnight.…”

Section: Assessing and Testing Products Designed For Sensitive Skinmentioning

confidence: 99%

Cosmetic selection in the sensitive-skin patient

Draelos

2001

Dermatol Ther

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The incidence of sensitive skin is increasing with great rapidity in the United States and Japan. This increase may be due in part to recognition of the condition, an increase in the number of skin products used on a daily basis by persons in developed countries, and other unidentified influences. Sensitive skin may be due to enhanced immune responsiveness, altered neurosensory input, and/or diminished barrier function. Guidelines for cosmetic and skin care product selection in the sensitive‐skin patient include a paucity of ingredients, a minimum of potential allergens, a reduction in cutaneous irritants, and restoration of the cutaneous barrier. This article presents a thought pattern for addressing cosmetics issues in the sensitive‐skin patient.

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Defining the Susceptibility of Acne-Prone and Sensitive Skin Populations to Extrinsic Factors

Cited by 35 publications

References 17 publications

What Is Sensitive Skin? A Systematic Literature Review of Objective Measurements

What Is Sensitive Skin? A Systematic Literature Review of Objective Measurements

Sensitive skin: an epidemiological study

Cosmetic selection in the sensitive-skin patient

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