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Cited by 4 publications
(2 citation statements)
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References 7 publications
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“…Moreover, opioid use and addiction appear particularly pertinent to T2D and obesity as similar pathophysiologic pathways are implicated in drug and food addiction, likely involving the gut-brain axis [ 15 ]. The neuropeptide hormone oxytocin (OXT) is emerging as an important part of the gut-brain axis and as a promising treatment of obesity, T2D, and addiction [ 2 , 16 20 ]. OXT synthesis in the brain hypothalamus is regulated by leptin, insulin, and dopaminergic pathways, which are particularly relevant to obesity, glucose metabolism, and addiction [ 16 , 17 ].…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Moreover, opioid use and addiction appear particularly pertinent to T2D and obesity as similar pathophysiologic pathways are implicated in drug and food addiction, likely involving the gut-brain axis [ 15 ]. The neuropeptide hormone oxytocin (OXT) is emerging as an important part of the gut-brain axis and as a promising treatment of obesity, T2D, and addiction [ 2 , 16 20 ]. OXT synthesis in the brain hypothalamus is regulated by leptin, insulin, and dopaminergic pathways, which are particularly relevant to obesity, glucose metabolism, and addiction [ 16 , 17 ].…”
Section: Introductionmentioning
confidence: 99%
“…In addition, OXT signaling may be connected to gut microbiota. For example, feeding mice with Lactobacillus reuteri resulted in a significant up-regulation of plasma levels of oxytocin and associated surge in grooming behavior [ 2 , 18 ].…”
Section: Introductionmentioning
confidence: 99%