Deficits in haptic perception and right parietal theta power changes in patients with anorexia nervosa before and after weight gain

Abstract

The quality of reproduction of the haptic stimuli and the theta-power changes indicate a cortical dysfunction and deficits in somatosensory integration processing of the right parietal cortex in AN patients even after weight gain.

Haptic Perception in Extreme Obesity: qEEG Study Focused on Predictive Coding and Body Schema

“…Noteworthy, a further finding is that, at the beginning of exploration, OBS showed a significantly lower theta, alpha and beta power in the right hemisphere in comparison with CTR, especially in temporo-parietal regions. In agreement with the results obtained in previous studies on anorectic patients [13,14], our study revealed that extreme obese participants have lower theta power in the right posterior hemisphere, especially during the beginning of the exploration. Whereas, in contrast to what occurred in the lower frequency bands, gamma activity in the OBS group was enhanced across the left fronto-central channels, in all the experimental intervals (Figure 5A,B).…”

Haptic Perception in Extreme Obesity: qEEG Study Focused on Predictive Coding and Body Schema

“…Noteworthy, a further finding is that, at the beginning of exploration, OBS showed a significantly lower theta, alpha and beta power in the right hemisphere in comparison with CTR, especially in temporo-parietal regions. In agreement with the results obtained in previous studies on anorectic patients [13,14], our study revealed that extreme obese participants have lower theta power in the right posterior hemisphere, especially during the beginning of the exploration. Whereas, in contrast to what occurred in the lower frequency bands, gamma activity in the OBS group was enhanced across the left fronto-central channels, in all the experimental intervals (Figure 5A,B).…”

White matter alterations in anorexia nervosa: Evidence from a voxel-based meta-analysis

“…Abnormal structural connectivity in these regions involved in body-image information processing might explain distorted body perception, a key feature in AN (2). Our findings also support the notion that parietal abnormalities in AN possibly lead to difficulties in haptic perception and spatial processing tasks (37,38). Furthermore, two of the studies that did not meet criteria for inclusion in our meta-analysis found differences in areas associated with body self-image.…”

Intellectual Function in Patients with Anorexia Nervosa and Bulimia Nervosa

“…Findings from the present study indicate that patients with AN and BN may not exhibit elevated intelligence (FIQ ≥ 110), as described in several previous studies (Blanz, Detzner, Lay, Rose, & Schmidt, ; Connan et al, ; Davies, Swan, Schmidt, & Tchanturia, ; Dickson et al, ; Grunwald et al, ; Hambrook, Brown, & Tchanturia, ; Holliday, Tchanturia, Landau, Collier, & Treasure, ; Liao et al, ; Lopez et al, ; Seed, Dixon, McCluskey, & Young, ; Southgate, Tchanturia, & Treasure, ; Tchanturia et al, ; Tchanturia et al, ; Tchanturia et al, ). This discrepancy might be caused, to some degree, by methodological differences.…”

Haptic Perception in Extreme Obesity: qEEG Study Focused on Predictive Coding and Body Schema

“…Noteworthy, a further finding is that, at the beginning of exploration, OBS showed a significantly lower theta, alpha and beta power in the right hemisphere in comparison with CTR, especially in temporo-parietal regions. In agreement with the results obtained in previous studies on anorectic patients [13,14], our study revealed that extreme obese participants have lower theta power in the right posterior hemisphere, especially during the beginning of the exploration. Whereas, in contrast to what occurred in the lower frequency bands, gamma activity in the OBS group was enhanced across the left fronto-central channels, in all the experimental intervals (Figure 5A,B).…”

White matter alterations in anorexia nervosa: Evidence from a voxel-based meta-analysis

“…Abnormal structural connectivity in these regions involved in body-image information processing might explain distorted body perception, a key feature in AN (2). Our findings also support the notion that parietal abnormalities in AN possibly lead to difficulties in haptic perception and spatial processing tasks (37,38). Furthermore, two of the studies that did not meet criteria for inclusion in our meta-analysis found differences in areas associated with body self-image.…”

Intellectual Function in Patients with Anorexia Nervosa and Bulimia Nervosa

“…Findings from the present study indicate that patients with AN and BN may not exhibit elevated intelligence (FIQ ≥ 110), as described in several previous studies (Blanz, Detzner, Lay, Rose, & Schmidt, ; Connan et al, ; Davies, Swan, Schmidt, & Tchanturia, ; Dickson et al, ; Grunwald et al, ; Hambrook, Brown, & Tchanturia, ; Holliday, Tchanturia, Landau, Collier, & Treasure, ; Liao et al, ; Lopez et al, ; Seed, Dixon, McCluskey, & Young, ; Southgate, Tchanturia, & Treasure, ; Tchanturia et al, ; Tchanturia et al, ; Tchanturia et al, ). This discrepancy might be caused, to some degree, by methodological differences.…”

Haptic Perception in Extreme Obesity: qEEG Study Focused on Predictive Coding and Body Schema

“…Noteworthy, a further finding is that, at the beginning of exploration, OBS showed a significantly lower theta, alpha and beta power in the right hemisphere in comparison with CTR, especially in temporo-parietal regions. In agreement with the results obtained in previous studies on anorectic patients [13,14], our study revealed that extreme obese participants have lower theta power in the right posterior hemisphere, especially during the beginning of the exploration. Whereas, in contrast to what occurred in the lower frequency bands, gamma activity in the OBS group was enhanced across the left fronto-central channels, in all the experimental intervals (Figure 5A,B).…”

White matter alterations in anorexia nervosa: Evidence from a voxel-based meta-analysis

“…Abnormal structural connectivity in these regions involved in body-image information processing might explain distorted body perception, a key feature in AN (2). Our findings also support the notion that parietal abnormalities in AN possibly lead to difficulties in haptic perception and spatial processing tasks (37,38). Furthermore, two of the studies that did not meet criteria for inclusion in our meta-analysis found differences in areas associated with body self-image.…”

Intellectual Function in Patients with Anorexia Nervosa and Bulimia Nervosa

“…Findings from the present study indicate that patients with AN and BN may not exhibit elevated intelligence (FIQ ≥ 110), as described in several previous studies (Blanz, Detzner, Lay, Rose, & Schmidt, ; Connan et al, ; Davies, Swan, Schmidt, & Tchanturia, ; Dickson et al, ; Grunwald et al, ; Hambrook, Brown, & Tchanturia, ; Holliday, Tchanturia, Landau, Collier, & Treasure, ; Liao et al, ; Lopez et al, ; Seed, Dixon, McCluskey, & Young, ; Southgate, Tchanturia, & Treasure, ; Tchanturia et al, ; Tchanturia et al, ; Tchanturia et al, ). This discrepancy might be caused, to some degree, by methodological differences.…”