Déficit de vitamina D en la fractura osteoporótica de cadera y factores asociados

Larrosa, M.; Casado, Enrique; Gómez, Antonio; Moreno, Mireia; Berlanga, Eugenio; Ramon, Jordi; Gratacós, Jordi

doi:10.1157/13114538

Cited by 18 publications

(4 citation statements)

References 26 publications

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“…The significant relation of low bone density and vitamin D deficiency is consistent with that reported by Napoli et al, 20 Rossini et al, 21 and Larrosa et al 22 …”

Section: Discussionsupporting

confidence: 90%

Hypovitaminosis D Among Patients Admitted With Hip Fracture to a Level-1 Trauma Center in the Sunny Upper Egypt

Farouk

Mahran

Said

et al. 2016

Geriatr Orthop Surg Rehabil

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Introduction:Despite abundant sunshine, hypovitaminosis D is common in the Middle East. The aim of this study was to determine the prevalence of hypovitaminosis D and related correlates among patients with hip fracture in Assiut University Hospitals in Upper Egypt.Materials and Methods:A cross-sectional study was carried out in 133 patients with hip fracture, aged 50 years and older, admitted to Trauma Unit of Assiut University Hospitals, from January through December 2014. Patients were selected by systematic random sampling. Serum 25-hydroxy vitamin D level was measured by enzyme-linked immunosorbent assay; bone mineral density (BMD) by dual-energy X-ray absorptiometry. Weight and height measurements were used for body mass index (BMI) calculation.Results:Patients’ median age was 70 years (range: 50-99); 51.9% were females. Osteoporosis (femoral neck T score: <−2.5 standard deviation) prevalence was 72.2%. Of all patients, 60.9% had vitamin D deficiency (<20 ng/mL); 15.8% reported vitamin D inadequacy (from 20 to 29 ng/mL) and vitamin D levels were normal in 23.3% (>30 ng/mL). According to univariate analysis, vitamin D deficiency was significantly associated with obesity (P = .012) and low T scores of the femoral neck (P = .001), L2 (P = .021), L3 (P = .031), L4 (P = .012), and the greater trochanter (P < .001). In a multivariable logistic regression model, high BMI and low BMD of the femoral neck and greater trochanter were associated with hypovitaminosis D.Conclusion:Prevalence of hypovitaminosis D is high among patients with hip fracture and associated with low BMD and high BMI. Increasing awareness about prevention as well as detection and treatment of vitamin D deficiency is recommended.

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“…The significant relation of low bone density and vitamin D deficiency is consistent with that reported by Napoli et al, 20 Rossini et al, 21 and Larrosa et al 22 …”

Section: Discussionsupporting

confidence: 90%

Hypovitaminosis D Among Patients Admitted With Hip Fracture to a Level-1 Trauma Center in the Sunny Upper Egypt

Farouk

Mahran

Said

et al. 2016

Geriatr Orthop Surg Rehabil

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“…The prevalence of hypovitaminosis D in osteoporotic hip fracture patients is high and secondary hyperparathyroidism is observed in more than half of the cases. In patients with low sunlight exposure and low nutritional and functional status, vitamin D deficiency is particularly prevalent [11]. About three-quarters of patients with hip fractures have vitamin D deficiency and two-thirds have secondary hyperparathyroidism.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Vitamin D Levels and Its Correlation With Osteoporosis and Fracture Site Comminution in Osteoporotic Hip Fractures in Tertiary Care Hospital

Vellingiri¹,

Ethiraj²,

Nagakumar³

et al. 2021

Cureus

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Introduction: A global concern is vitamin D deficiency and insufficiency. There is a particularly high risk for pregnant women, people of color (Blacks, Hispanics, and those with increased skin melanin pigmentation), obese children and adults, and children and adults who are abstinent from direct sun exposure. The goal of this study was to understand the incidence of vitamin D deficiency in patients with osteoporotic hip fractures in our rural population and also to know its association with osteoporosis and osteoporotic hip fractures in a tertiary care trauma center. Methods: This prospective research was performed at our tertiary trauma treatment center in Kolar, Karnataka, India by the Department of Orthopedics from September 2019 and July 2020. The age category was 45-90 years, intertrochanteric fractures were graded using the Boyd and Griffin classification and femoral neck fractures the Garden's staging. The research included all patients with fractures after a trivial trauma such as slip and fall while standing/walking and excluded patients with a serious history of trauma such as road traffic accidents/falls from height and pathological fractures. This study involved 30 patients. Age and gender, type of fracture, vitamin D levels, Singh’s index, and comminution of fracture site were reported in patient demographics. Results: Thirty patients comprised the study population. Most of them were female. Females comprised 18 out of the 30. There were twelve, thirteen, and five persons in our sample population between the ages of 45-60, 61-75, and >75 years. The Singh's index was tabulated. Mean vitamin D levels were 9.64+/-3.23 in the femur fracture group and 13.42+/-5.31 in the intertrochanteric fracture group. Mean levels of vitamin D are included as a graphical representation. The comminution of the fracture site in groups of the femur and intertrochanteric fractures was eight and six, respectively. Conclusion: Early diagnosis and treatment of these patients with vitamin D for osteomalacia and anti-osteoporotic osteoporosis regimens will hopefully enhance bone, muscle, and general health, minimizing falls and fractures.

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“…Es interesante remarcar que las mujeres con fracturas vertebrales tambié n presentaron una alta prevalencia de valores bajos de 25-OH-D y una mayor frecuencia de alteraciones en los pará metros del metabolismo mineral. De hecho, el 88% de estas mujeres tenían al menos una alteració n asociada, incluyendo un aumento del marcador de resorció n, de PTH o valores sé ricos bajos de vitamina D, siendo este ú ltimo el trastorno má s frecuente en este grupo de pacientes, un hallazgo que coincide con los resultados de otros estudios en los que destaca la alta prevalencia de dé ficit de vitamina D en individuos con fracturas 22 . A pesar de que el dé ficit de vitamina D se ha relacionado previamente con una disminució n de la DMO y con un incremento del riesgo de fracturas [23][24][25][26] , algunos estudios no han encontrado una asociació n significativa entre los valores sé ricos de vitamina D y dicho riesgo 27,28 .…”

Section: Discusió Nunclassified

Identificación de las características clínicas y alteraciones analíticas asociadas a la fractura vertebral en mujeres con osteoporosis posmenopáusica

Cerdá¹,

Peris²,

Monegal³

et al. 2012

Medicina Clínica

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Déficit de vitamina D en la fractura osteoporótica de cadera y factores asociados

Cited by 18 publications

References 26 publications

Hypovitaminosis D Among Patients Admitted With Hip Fracture to a Level-1 Trauma Center in the Sunny Upper Egypt

Hypovitaminosis D Among Patients Admitted With Hip Fracture to a Level-1 Trauma Center in the Sunny Upper Egypt

Assessment of Vitamin D Levels and Its Correlation With Osteoporosis and Fracture Site Comminution in Osteoporotic Hip Fractures in Tertiary Care Hospital

Identificación de las características clínicas y alteraciones analíticas asociadas a la fractura vertebral en mujeres con osteoporosis posmenopáusica

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