Deep6: Classification of Metatranscriptomic Sequences into Cellular Empires and Viral Realms Using Deep Learning Models

Abstract

Deep6 is a deep learning model that classifies metatranscriptomic sequences as short as 250 nucleotides into prokaryotes, eukaryotes, or one of the four viral realms, using a reference-independent and alignment-free approach. Average accuracies range from 0.87 to 0.97, depending on sequence length.