Deep eutectic solvent-assisted fabrication of bioinspired 3D carbon–calcium phosphate scaffolds for bone tissue engineering

Wysokowski, Marcin; Machałowski, Tomasz; Idaszek, Joanna; Chlanda, Adrian; Jaroszewicz, Jakub; Heljak, Marcin; Niemczak, Michał; Piasecki, Adam; Gajewska, Marta; Ehrlich, Hermann; Święszkowski, Wojciech; Jesionowski, Teofil

doi:10.1039/d3ra02356g

Cited by 3 publications

(3 citation statements)

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“…These materials can encompass a wide range of compositions, including metal-organic frameworks, hybrid perovskites, and functional nanocomposites, each tailored for specific applications. [33,34] In catalysis, NADESs serve as efficient and tunable reaction media, facilitating improved selectivity and yield in a range of chemical transformations. Their solubilization capabilities make them valuable in extraction processes for both organic and inorganic compounds, with applications in the purification of natural products and environmental remediation.…”

Section: Components and Methodology Used For Nadesmentioning

confidence: 99%

“…By harnessing the synergistic interactions between inorganic and organic components within DESs, researchers have been able to synthesize hybrid materials exhibiting enhanced performance characteristics. These materials can encompass a wide range of compositions, including metal–organic frameworks, hybrid perovskites, and functional nanocomposites, each tailored for specific applications [33,34] …”

Section: Components and Methodology Used For Nadesmentioning

confidence: 99%

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Natural Deep Eutectic Solvents (NADES): Manufacture, Characteristics, and Their Significance as Designer Solvents

Satija,

Chambyal,

Singh

et al. 2024

ChemistrySelect

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To replace the hazardous organic solvents currently in use, one of the key objectives of green chemistry has been the development of green solvents obtained from natural sources. Natural deep eutectic solvents (NADES) are bio‐based natural compounds, namely primary metabolites like organic acids, sugar, alcohols, amines, and amino acids, which are acceptable to the environment and may eventually replace the conventionally used harsh organic solvents. This study focuses on the recent developments in the realm of these innovative materials as well as the conventional deep eutectic solvents (DES)‐based techniques. A more in‐depth examination of DES's applications in various chemical processes is covered after a description of its definition, manufacture, and unique characteristics. Their significance as designer solvents in various organic reactions and their impact on production methods are addressed.

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Section: Components and Methodology Used For Nadesmentioning

confidence: 99%

Section: Components and Methodology Used For Nadesmentioning

confidence: 99%

Natural Deep Eutectic Solvents (NADES): Manufacture, Characteristics, and Their Significance as Designer Solvents

Satija,

Chambyal,

Singh

et al. 2024

ChemistrySelect

View full text Add to dashboard Cite

show abstract

“…In line with previous research, we also explore the following: "for the purpose of this review, composites are defined as those having a distinct phase distributed through their bulk, as opposed to modular or coated components" ( [40], p. 1329). Therefore, with a few exceptions, we did not consider CaPO 4 deposits produced on different materials by various deposition techniques [41][42][43][44][45][46] or CaPO 4 coated with other compounds [47][48][49][50][51]. However, we did include composite coatings.…”

Section: General Knowledge and Experiencementioning

confidence: 99%

Calcium Orthophosphate (CaPO4) Containing Composites for Biomedical Applications: Formulations, Properties, and Applications

Dorozhkin

2024

J. Compos. Sci.

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The goal of this review is to present a wide range of hybrid formulations and composites containing calcium orthophosphates (abbreviated as CaPO4) that are suitable for use in biomedical applications and currently on the market. The bioactive, biocompatible, and osteoconductive properties of various CaPO4-based formulations make them valuable in the rapidly developing field of biomedical research, both in vitro and in vivo. Due to the brittleness of CaPO4, it is essential to combine the desired osteologic properties of ceramic CaPO4 with those of other compounds to create novel, multifunctional bone graft biomaterials. Consequently, this analysis offers a thorough overview of the hybrid formulations and CaPO4-based composites that are currently known. To do this, a comprehensive search of the literature on the subject was carried out in all significant databases to extract pertinent papers. There have been many formulations found with different material compositions, production methods, structural and bioactive features, and in vitro and in vivo properties. When these formulations contain additional biofunctional ingredients, such as drugs, proteins, enzymes, or antibacterial agents, they offer improved biomedical applications. Moreover, a lot of these formulations allow cell loading and promote the development of smart formulations based on CaPO4. This evaluation also discusses basic problems and scientific difficulties that call for more investigation and advancements. It also indicates perspectives for the future.

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Evaluation of osteoconductive effect of polycaprolactone (PCL) scaffold treated with fibronectin on adipose-derived mesenchymal stem cells (AD-MSCs)

Rezaee Asl

2024

Am J Stem Cells

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Deep eutectic solvent-assisted fabrication of bioinspired 3D carbon–calcium phosphate scaffolds for bone tissue engineering

Abstract: Modification of 3D spongin-derived carbon with tricalcium phosphate achieved in a deep eutectic solvent. The 3D carbon–tricalcium phosphate scaffold shows great potential for stem cell-based tissue engineering.

Cited by 3 publications

References 84 publications

Natural Deep Eutectic Solvents (NADES): Manufacture, Characteristics, and Their Significance as Designer Solvents

Natural Deep Eutectic Solvents (NADES): Manufacture, Characteristics, and Their Significance as Designer Solvents

Calcium Orthophosphate (CaPO4) Containing Composites for Biomedical Applications: Formulations, Properties, and Applications

Evaluation of osteoconductive effect of polycaprolactone (PCL) scaffold treated with fibronectin on adipose-derived mesenchymal stem cells (AD-MSCs)

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