Decreased plasma adiponectin concentrations in patients with syndrome X

Abstract

Serum adiponectin levels were lower in patients with syndrome X, and these low adiponectin concentrations may cause endothelial dysfunction. Thus, patients with a marked drop in adiponectin levels may be considered at high risk for future coronary events and may therefore benefit from additional pharmacological treatment.

The Role of Myocardial Perfusion Gated SPECT Study in Women with Coronary Artery Disease: A Correlative Study

“…Similar to our results, Sanlı et al (32) and Adamu et al (10) reported that myocardial perfusion defects on MPS study were related with true ischemia localising on where insignificant stenosis was detected by invasive CAG, and stated that, stress MPS has incremental predictive value for future events in patients without significant CAD. Gated MPS is a useful test to determine especially metabolic syndrome and/or microvascular disease in women who are admitted with atypical cardiac symptoms (10,12,32). Gated study provides that myocardial perfusion defects and functional abnormalities can be simultaneuosly evaluated and attenuation artifacts can be differentiated from real perfusion abnormality.…”

“…Additionally, defining the degree of stenosis in invasive CAG is dependent on operator experience and does not give information about myocardial perfusion. As previously reported, invasive CAG is not adequate to differentiate metabolic syndrome or microvascular disorders yet (11,12,13). To determine regional myocardial perfusion abnormalities and help diagnose metabolic syndrome, MPS study is a valuable method but soft tissue attenuations on scintigraphic images are major limitations.…”