Decreased mortality but increased morbidity in neonates with jejunoileal atresia; a study of 114 cases over a 34-year period

Stollman, Thamar H.; Blaauw, Ivo de; Wijnen, Marc H. W. A.; Staak, F.H.J.M. van der; Rieu, P.N.M.A.; Draaisma, Jos M. Th.; Wijnen, René

doi:10.1016/j.jpedsurg.2008.10.043

Cited by 114 publications

(148 citation statements)

References 18 publications

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“…It can occur at any age from new born period to infants or even adulthood. The reported frequency of NIO ranges from 0.4 to 3.1/10,000 live births (1)(2)(3)(4)(5) . the etiology of obstruction varies greatly; with common aetiologies such as intestinal atresia, meconium ileus, hirschsprung disease and malrotation of gut with or without volvulus (6) .…”

Section: Introductionmentioning

confidence: 99%

Etiological Spectrum of Neonates Presenting With Intestinal Obstruction at A Tertiary Care Centre

Nagpure¹

2016

jmscr

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Section: Introductionmentioning

confidence: 99%

Etiological Spectrum of Neonates Presenting With Intestinal Obstruction at A Tertiary Care Centre

Nagpure¹

2016

jmscr

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“…One of the three portions of the jejunum twists around the marginal artery of the colon and causes an atresia. Symptoms in this disorder include vomiting, abdominal distension and constipation 16,19 . These were confi rmed in the present study.…”

Section: Discussionmentioning

confidence: 99%

“…The largest study of neonates with jejunoileal atresia showed that short bowel syndrome seems to be the biggest problem resulting in long hospital stay, more feeding problems and higher mortality and morbidity 1,14, 19 . Managing children with short bowel has however improved because of the use of total parentral nutrition (which is not available in our environment), new operative techniques, and better intensive care 19 .…”

Section: Discussionmentioning

confidence: 99%

“…Managing children with short bowel has however improved because of the use of total parentral nutrition (which is not available in our environment), new operative techniques, and better intensive care 19 . These are not readily available in this setting which can thus explain the high mortality rate we had.…”

Section: Discussionmentioning

confidence: 99%

“…These are not readily available in this setting which can thus explain the high mortality rate we had. Though survival has increased in the last 15 years, it has cost the surviving neonates a high percentage of late complications 19 . Patients usually die from short bowel syndrome which can probably explain the deaths we had in this case series and complications related to total parenteral nutrition 2 .…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Apple Peel Small Bowel, A Review of Four Cases: Surgical and Radiographic Aspects

Akinola

Osuoji

2011

J. Nepal Paedtr. Soc.

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Background: Although apple peel intestinal atresia is rare and is associated with a high mortality and morbidity, there is a dearth of its report in African literature. This study reviews four of the cases seen in a state teaching hospital in Lagos, considering the radiographic findings, surgical management and outcome. A brief review of literature is also undertaken. Aims and Objectives: To correle the plain radiographic findings with the surgical findings of neonates gathered over a six year period and to evaluate their surgical management, hoping to further help improve management of such neonates' in future in resource limited regions such as ours. Methodology: It was a retrospective case series of four neonates who were brought in over a period of six years and operated after an initial plain abdominal X-ray. They were done as emergency cases, consent was obtained from their parents and the study was approved by the research and ethics committee. Operative findings were subsequently correlated with their radiographic findings and the surgical outcomes and follow up were documented. Conclusion: This study revealed that "the triple bubble sign" is a common radiographic finding in Apple Peel deformities, as well as gangrene of the jejunum and ileum at surgery.

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Gastrointestinal Tract: Congenital Abnormalities

Fotis

Burns

Thapar

2012

Encyclopedia of Life Sciences

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The gastrointestinal tract may be subject to a variety of congenital abnormalities (i.e. those present at birth) that arise during embryological development. Specific patterns of malformations of the gastrointestinal tract include abnormal lumenisation (stenoses and atresias), duplications, abnormal rotation and fixation, abdominal defects and a variety of others associated with persistence of embryonic structures (e.g. Meckel's diverticulum), or abnormal formation of specific regions of the gastrointestinal tract (e.g. microgastria) or its cellular components (e.g. nerves in Hirschsprung's disease). These disorders primarily result in symptoms of intestinal obstruction, effects on surrounding structures or of associated anomalies. Early recognition is vital and management consists of timely resuscitation and stabilisation of the patients before institution of definitive surgical therapies. Key Concepts: The gastrointestinal tract is composed of anatomically and functionally distinct regions. The structure of gastrointestinal tract is formed by a complex series of processes that occur to the initial simple gut tube including elongation, herniation out of the abdominal cavity, rotation and fixation. A variety of genes working in isolation or in concert orchestrate the various facets of gut development. A failure in any of the various embryological processes that form the gut can lead to congenital abnormalities, which range from extremely rare to relatively common. Many of these abnormalities are associated with other congenital anomalies. Clinically, most present soon after birth with symptoms of intestinal obstruction or of associated anomalies. Early clinical recognition of these disorders is essential to minimise complications and allow the early institution of appropriate therapies. Although surgery is the commonest intervention early treatment must include adequate resuscitation and stabilisation of the child prior to definitive surgery.

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Decreased mortality but increased morbidity in neonates with jejunoileal atresia; a study of 114 cases over a 34-year period

Cited by 114 publications

References 18 publications

Etiological Spectrum of Neonates Presenting With Intestinal Obstruction at A Tertiary Care Centre

Etiological Spectrum of Neonates Presenting With Intestinal Obstruction at A Tertiary Care Centre

Apple Peel Small Bowel, A Review of Four Cases: Surgical and Radiographic Aspects

Gastrointestinal Tract: Congenital Abnormalities

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