Decongestants, antihistamines and nasal irrigation for acute sinusitis in children

Histamine and H1-antihistamines: Celebrating a century of progress

“…[76][77][78][79][80][81][82][83][84][85][86][87][88][89][90][91] Atopic dermatitis. Histamine acts as a pruritogen through H 4 -receptors in patients with atopic dermatitis, and other mediators, including IL-31 and other cytokines, play an important role.…”

“…H 1 -antihistamines are used to treat symptoms of upper respiratory tract infections, acute otitis media, otitis media with effusion, sinusitis, nasal polyps, nonspecific cough, and nonallergic, nonspecific itching; however, their efficacy and safety have not been confirmed in high-quality randomized controlled trials in patients with any of these disorders. 1,18,57,[80][81][82][83][84][85] Central nervous system and vestibular disorders…”

Histamine and H1-antihistamines: Celebrating a century of progress

“…[76][77][78][79][80][81][82][83][84][85][86][87][88][89][90][91] Atopic dermatitis. Histamine acts as a pruritogen through H 4 -receptors in patients with atopic dermatitis, and other mediators, including IL-31 and other cytokines, play an important role.…”

“…H 1 -antihistamines are used to treat symptoms of upper respiratory tract infections, acute otitis media, otitis media with effusion, sinusitis, nasal polyps, nonspecific cough, and nonallergic, nonspecific itching; however, their efficacy and safety have not been confirmed in high-quality randomized controlled trials in patients with any of these disorders. 1,18,57,[80][81][82][83][84][85] Central nervous system and vestibular disorders…”

Utilização de medicamentos em crianças internadas em um hospital geral

“…Algumas revisões sistemáticas têm demonstrado que alguns desses medicamentos não apresentam benefício significativamente superior ao placebo no tratamento de síndromes das infecções de vias áreas superiores, como congestão nasal e rinorreia [40,41], tosse crônica inespecífica [42] e sinusite aguda [43]. Tais dados retratam a cultura regional de prevenir e tratar quadros de dor e febre, os quais muitas vezes podem ser contornados com medidas não medicamentosas [44].…”

Choice of Silver Drugs in Therapy of Rhinosinusitis at Children Age

“…Как при острых, так и при хронических риносинуситах активно используются препараты с секретолитической активностью [16,17]. На современном этапе фармакологами разработано большое количество синтетических лекарственных средств, призванных улучшить эвакуацию патологического секрета со слизистых оболочек дыхательных путей.…”

Histamine and H1-antihistamines: Celebrating a century of progress

“…[76][77][78][79][80][81][82][83][84][85][86][87][88][89][90][91] Atopic dermatitis. Histamine acts as a pruritogen through H 4 -receptors in patients with atopic dermatitis, and other mediators, including IL-31 and other cytokines, play an important role.…”

“…H 1 -antihistamines are used to treat symptoms of upper respiratory tract infections, acute otitis media, otitis media with effusion, sinusitis, nasal polyps, nonspecific cough, and nonallergic, nonspecific itching; however, their efficacy and safety have not been confirmed in high-quality randomized controlled trials in patients with any of these disorders. 1,18,57,[80][81][82][83][84][85] Central nervous system and vestibular disorders…”

Utilização de medicamentos em crianças internadas em um hospital geral

“…Algumas revisões sistemáticas têm demonstrado que alguns desses medicamentos não apresentam benefício significativamente superior ao placebo no tratamento de síndromes das infecções de vias áreas superiores, como congestão nasal e rinorreia [40,41], tosse crônica inespecífica [42] e sinusite aguda [43]. Tais dados retratam a cultura regional de prevenir e tratar quadros de dor e febre, os quais muitas vezes podem ser contornados com medidas não medicamentosas [44].…”

Choice of Silver Drugs in Therapy of Rhinosinusitis at Children Age

“…Как при острых, так и при хронических риносинуситах активно используются препараты с секретолитической активностью [16,17]. На современном этапе фармакологами разработано большое количество синтетических лекарственных средств, призванных улучшить эвакуацию патологического секрета со слизистых оболочек дыхательных путей.…”

Histamine and H1-antihistamines: Celebrating a century of progress

“…[76][77][78][79][80][81][82][83][84][85][86][87][88][89][90][91] Atopic dermatitis. Histamine acts as a pruritogen through H 4 -receptors in patients with atopic dermatitis, and other mediators, including IL-31 and other cytokines, play an important role.…”

“…H 1 -antihistamines are used to treat symptoms of upper respiratory tract infections, acute otitis media, otitis media with effusion, sinusitis, nasal polyps, nonspecific cough, and nonallergic, nonspecific itching; however, their efficacy and safety have not been confirmed in high-quality randomized controlled trials in patients with any of these disorders. 1,18,57,[80][81][82][83][84][85] Central nervous system and vestibular disorders…”

Utilização de medicamentos em crianças internadas em um hospital geral

“…Algumas revisões sistemáticas têm demonstrado que alguns desses medicamentos não apresentam benefício significativamente superior ao placebo no tratamento de síndromes das infecções de vias áreas superiores, como congestão nasal e rinorreia [40,41], tosse crônica inespecífica [42] e sinusite aguda [43]. Tais dados retratam a cultura regional de prevenir e tratar quadros de dor e febre, os quais muitas vezes podem ser contornados com medidas não medicamentosas [44].…”

Choice of Silver Drugs in Therapy of Rhinosinusitis at Children Age

“…Как при острых, так и при хронических риносинуситах активно используются препараты с секретолитической активностью [16,17]. На современном этапе фармакологами разработано большое количество синтетических лекарственных средств, призванных улучшить эвакуацию патологического секрета со слизистых оболочек дыхательных путей.…”