Deciphering
Staphylococcus aureus–
host dynamics using dual activity-based protein profiling of ATP-interacting proteins
Stephen Dela Ahator,
Kristin Hegstad,
Christian S. Lentz
et al.
Abstract:The utilization of ATP within cells plays a fundamental role in cellular processes that are essential for the regulation of host–pathogen dynamics and the subsequent immune response. This study focuses on ATP-binding proteins to dissect the complex interplay between
Staphylococcus aureus
and human cells, particularly macrophages (THP-1) and keratinocytes (HaCaT), during an intracellular infection. A snapshot of the various protein activity and function is provided using a desthiobio… Show more
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