The number of reported deaths from coronavirus disease 2019 (COVID-19) in the US was nearly 205 000 on September 28, 2020. 1 A month earlier, on August 13, 2020, a New York Times analysis of estimates from the Centers for Disease Control and Prevention reported that across the US, at least 200 000 more people had died than expected (based on rates in the past 5 years), between March and late July, and that these estimated deaths were approximately 60 000 higher than the number of deaths that were directly linked to the coronavirus. 2 In this issue of JAMA, Woolf et al 3 corroborate these findings in their analysis of data from the National Center for Health Statistics, confirming that due to incomplete and undocumented data, the number of publicly reported deaths from COVID-19 likely underestimates the actual death toll. The authors estimated that between March 1 and August 1, 2020, a 5-month period, there were 225 000 excess deaths. Of these deaths, they estimate that 65% can be attributed to COVID-19 and the remaining 35% to other conditions, such as diabetes, heart disease, Alzheimer disease, and cerebrovascular disease. By the end of the year it is likely that the total number of excess deaths in 2020 in comparison to the previous years will be greater than 400 000primarily attributable to the COVID-19 pandemic.The implications of these excess deaths are sobering fortheentirecountry,yetareevenmoreprofoundforcommunities of color. Whether these excess deaths are due to nonrespiratory complications of COVID-19 or societal disruptions that reduced or delayed access to health care and worsened other social determinants of health, it is certain that individuals living in the US who are Black, Indigenous, Latino, or Pacific Islander have the highest per capita hospitalizationanddeathrates.OnAugust18,2020,theAmerican Public Media Research Lab reported that individuals who are Black, Indigenous, Latino, or Pacific Islander have experienced higher death rates than individuals who are White or Asian, and that if they had died of COVID-19 at the samerateasWhiteUSresidents,about19 500Black,8400 Latino, 600 Indigenous, and 70 Pacific Islander individuals in the US would still be alive. 4 As startling as these numbers are, the reality is likely worse because these numbers do not include the excess deaths that Woolf et al 3 have estimated or projections for all of 2020.Communities of color have borne the burden of excess deaths from health disparities for generations. In a recent review article, Jackman and Shauman 5 estimated that almost 7.7 million excess deaths occurred among Black individuals from 1900-1999. Although excess deaths were highest in the early decades of the 20th century, in subsequent decades, excess deaths declined only modestly. Over the course of the century, these excess deaths began to occur among older Black