DDT, DDE, and 1-hydroxypyrene levels in children (in blood and urine samples) from Chiapas and Oaxaca, Mexico

Abstract

The aim of this study was to evaluate the DDT, DDE, and 1-hydroxypyrene exposure levels of children living in communities located in southeastern Mexico. The study communities were Lacanja and Victoria in Chiapas state and Ventanilla in Oaxaca state. Children living in Lacanja had total blood DDT levels (mean ± SD, 29,039.6 ± 11,261.4 ng/g lipid) that were significantly higher than those of children in Victoria (10,220.5 ± 7,893.1 ng/g lipid) and Ventanilla (11,659.7 ± 6,683.7 ng/g lipid). With respect to the 1-hydroxypyrene levels in urine samples, the levels in Lacanja (4.8 ± 4.1 μg/L or 4.5 ± 3.9 μmol/mol creatinine) and Victoria (4.6 ± 3.8 μg/L or 3.9 ± 3.0 μmol/mol Cr) were significantly higher than levels found in Ventanilla (3.6 ± 1.4 μg/L or 2.5 ± 0.5 μmol/mol Cr). In conclusion, our data indicate high levels of exposure in children living in the communities studied in this work. The evidence found in this study could be further used as a trigger to revisit local policies on environmental exposures.

Expression levels of circulating microRNAs‐126, ‐155, and ‐145 in Mexican women exposed to polycyclic aromatic hydrocarbons through biomass fuel use

“…Data obtained in this investigation showed that the highest mean urinary 1‐OHP level was detected in women who use wood as their principal indoor fuel source for cooking and heating (0.55 ± 0.52 μmol/mol creatinine) (Table ). In line with our results, high urinary 1‐OHP levels have been detected in people chronically exposed to biomass smoke in different studies performed in Mexico (Martínez‐Salinas et al, ; Riojas‐Rodriguez et al, ; Martínez‐salinas et al, ; Pruneda‐Álvarez et al, ; Trejo‐Acevedo et al, , ; Jasso‐Pineda et al, ; Ruiz‐Vera et al, ). Besides, it has been demonstrated that urinary 1‐OHP levels in populations that use biomass combustion as an indoor fuel source is generally higher than those urinary 1‐OHP concentrations found in populations exposed to PAHs through other exposure sources such as vehicular traffic, occupational settings, industrial areas, among others (Chetiyanukornkul et al, ; Polanska et al, ; Yuan et al, ).…”

Effect of aerobic exercise intervention on DDT degradation and oxidative stress in rats

“…Dichlorodiphenyltrichloroethane (DDT), one of the typical persistent organic pollutants, was used worldwide in agricultural pest control and vector-borne disease control. Although the use of DDT has been limited internationally, its presence in unchanged or modified forms is still observed in the environment (water, sediment, and soil) (Dai et al, 2014, Turgut et al, 2013, Tang et al, 2014, Veljanoska-sarafiloska et al, 2013) and can even be detected in fodder plants (Yehouenou et al, 2013) in the bodies of animals (Deribe et al, 2013) and humans (Pérez-Maldonado et al, 2013, Teeyapant et al, 2014). This finding is attributed to its persistence, bioaccumulation, toxicity, and physical–chemical capacity for long-range transport (Aneck-Hahn et al, 2007, Sadasivaiah et al, 2007, Skinner et al, 2013).…”

Levels of Organochlorine Pesticides in Blood Plasma from Residents of Malaria-Endemic Communities in Chiapas, Mexico

“…Yáñez et al [ 13 ] reported that the breast milk from women living in Chiapas had higher levels of DDT and its main metabolite dichlorodiphenyldichloroethylene (DDE) than breast-feeding women from other states, including Oaxaca, Quintana Roo, and San Luis Potosi. Other studies have reported high levels of DDT and its metabolites in blood of children [ 3 , 4 , 14 , 15 ]. Notably, children in Chiapas had the highest levels of DDT and its metabolites out of all children participating in a study that covered several communities of Mesoamerican countries [ 3 ].…”