Danazol for uterine fibroids

Fibroid growth and medical options for treatment

“…However, data from the literature are limited (87,88) and tumor volume reduction has not been confirmed (89). This is probably the consequence of the multiple effects of progestins.…”

Fibroid growth and medical options for treatment

“…However, data from the literature are limited (87,88) and tumor volume reduction has not been confirmed (89). This is probably the consequence of the multiple effects of progestins.…”

Androgen Signaling in Uterine Diseases: New Insights and New Targets

“…Estrogen promotes the proliferation of uterine smooth muscle tissue by acting on ER [38]. Nevertheless, in vitro studies have shown that androgens are involved in the development of uterine fibroids as well (Figure 2) [39,40]. Wong et al found that both high levels of T and E2 were associated with an increased risk of developing uterine fibroids [41].…”

Ulipristal acetate: a novel pharmacological approach for the treatment of uterine fibroids

“……”

Fibroid growth and medical options for treatment

“…However, data from the literature are limited (87,88) and tumor volume reduction has not been confirmed (89). This is probably the consequence of the multiple effects of progestins.…”

Androgen Signaling in Uterine Diseases: New Insights and New Targets

“…Estrogen promotes the proliferation of uterine smooth muscle tissue by acting on ER [38]. Nevertheless, in vitro studies have shown that androgens are involved in the development of uterine fibroids as well (Figure 2) [39,40]. Wong et al found that both high levels of T and E2 were associated with an increased risk of developing uterine fibroids [41].…”

Ulipristal acetate: a novel pharmacological approach for the treatment of uterine fibroids

“……”

Fibroid growth and medical options for treatment

“…However, data from the literature are limited (87,88) and tumor volume reduction has not been confirmed (89). This is probably the consequence of the multiple effects of progestins.…”

Androgen Signaling in Uterine Diseases: New Insights and New Targets

“…Estrogen promotes the proliferation of uterine smooth muscle tissue by acting on ER [38]. Nevertheless, in vitro studies have shown that androgens are involved in the development of uterine fibroids as well (Figure 2) [39,40]. Wong et al found that both high levels of T and E2 were associated with an increased risk of developing uterine fibroids [41].…”

Ulipristal acetate: a novel pharmacological approach for the treatment of uterine fibroids

“……”