Daily variation of melatonin content in the optic lobes of the crab Neohelice granulata

Maciel, Fábio Everton; Geihs, Márcio Alberto; Vargas, Marcelo Alves; Cruz, Bruno Pinto; Ramos, Bianca Padovani; Vakkuri, Olli; Meyer-Rochow, Victor Benno; Nery, Luiz Eduardo Maia; Allodi, Silvana

doi:10.1016/j.cbpa.2007.11.007

Cited by 36 publications

(22 citation statements)

References 27 publications

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“…In the crab Neohelice granulata, melatonin contents of the optic lobes show two diel peaks of comparable values in the middle of both the light and the dark phases. This diurnal pattern, however, persists only in constant darkness, not under continuous illumination (268). Physiological studies on effects of melatonin in crustaceans are still scarce but apparently coming of age, although the exact cellular (neuronal) sources of melatonin are still unclear.…”

Section: Melatoninmentioning

confidence: 99%

Circadian clocks in crustaceans: identified neuronal and cellular systems

Strauß

Dircksen²

2010

Front Biosci

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Circadian rhythms are known for locomotory and reproductive behaviours, and the functioning of sensory organs, nervous structures, metabolism and developmental processes. The mechanisms and cellular bases of control are mainly inferred from circadian phenomenologies, ablation experiments and pharmacological approaches. Cellular systems for regulation summarised here comprise the retina, the eyestalk neuroendocrine X-organ-sinus gland system, several neuropeptides such as red pigment concentrating, hyperglycaemic and pigment-dispersing hormones, and factors such as serotonin and melatonin. No master clock has been identified, but a model of distributed clockwork involves oscillators such as the retinular cells, neurosecretory systems in the optic lobes, putative brain pacemakers, and the caudal photoreceptor. Extraretinal brain photoreceptors mediate entrainment. Comparative analyses of clock neurons and proteins known from insects may allow the identification of candidate clock neurons in crustaceans as putative homologues in the two taxa. Evidence for the existence of "insect-like" intracellular clock proteins and (light sensitive) transcription factors is scarce, but clock-, period-, and cryptochrome-gene products have been localised in the CNS and other organs rendering further investigations into crustacean clockwork very promising.

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Section: Melatoninmentioning

confidence: 99%

Circadian clocks in crustaceans: identified neuronal and cellular systems

Strauß

Dircksen²

2010

Front Biosci

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“…In invertebrates, the role of melatonin has not been studied extensively, though it has been detected in nearly every organism tested, including crustaceans (Balzer et al, 1997;Maciel et al, 2008;Tilden et al, 1997Tilden et al, , 2001Withyachumnarnkul et al, 1992Withyachumnarnkul et al, , 1999. A recent study by Cary et al (2012) showed that melatonin possesses both neuritogenesis and neuroprotective effects in crustacean X-organ cells.…”

Section: Introductionmentioning

confidence: 96%

Induction of ecdysteroidogenesis, methyl farnesoate synthesis and expression of ecdysteroid receptor and retinoid X receptor in the hepatopancreas and ovary of the giant mud crab, Scylla serrata by melatonin

Girish

Swetha

Reddy

2015

General and Comparative Endocrinology

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“…While melatonin has not been studied extensively in invertebrates, it has been detected in nearly every organism tested, including crustaceans (Balzer et al, 1997; Maciel et al, 2008; Markowska et al, 2009; Tilden et al, 1997, 2001b; Withyachumnarnkul et al, 1992, 1999). The eyestalks of crustaceans contain the optic lobes and the x-organ/sinus gland, a neuropeptide-secreting neurohemal structure that is analogous to the vertebrate hypothalamus-pituitary system in that its many hormone products regulate a variety of functions: molt-inhibiting hormone (MIH), the broadly-acting crustacean hyperglycemic hormone (CHH), red pigment concentrating hormone (RPCH), retinal light-adapting hormone (LAH) and dark-adapting hormone (DAH), crustacean cardioactive peptide (CCAP), methylfarnesoate-inhibiting peptide, and neurodepressing hormone (NDH) (for review: Christie et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Melatonin: Neuritogenesis and neuroprotective effects in crustacean x-organ cells

Cary¹,

Cuttler²,

Duda³

et al. 2012

Comparative Biochemistry and Physiology Part A: Molecular &

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Melatonin has both neuritogenic and neuroprotective effects in mammalian cell lines such as neuroblastoma cells. The mechanisms of action include receptor-coupled processes, direct binding and modulation of calmodulin and protein kinase C, and direct scavenging of free radicals. While melatonin is produced in invertebrates and has influences on their physiology and behavior, little is known about its mechanisms of action. We studied the influence of melatonin on neuritogenesis in well-differentiated, extensively-arborized crustacean x-organ neurosecretory neurons. Melatonin significantly increased neurite area in the first 24 h of culture. The more physiological concentrations, 1 nM and 1 pM, increased area at 48 h also, whereas the pharmacological 1μM concentration appeared to have desensitizing effects by this time. Luzindole, a vertebrate melatonin receptor antagonist, had surprising and significant agonist-like effects in these invertebrate cells. Melatonin receptors have not yet been studied in invertebrates. However, the presence of membrane-bound receptors in this population of crustacean neurons is indicated by this study. Melatonin also has significant neuroprotective effects, reversing the inhibition of neuritogenesis by 200 and 500 μM hydrogen peroxide. Because this is at least in part a direct action not requiring a receptor, melatonin’s protection from oxidative stress is not surprisingly phylogenetically-conserved.

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Daily variation of melatonin content in the optic lobes of the crab Neohelice granulata

Cited by 36 publications

References 27 publications

Circadian clocks in crustaceans: identified neuronal and cellular systems

Circadian clocks in crustaceans: identified neuronal and cellular systems

Induction of ecdysteroidogenesis, methyl farnesoate synthesis and expression of ecdysteroid receptor and retinoid X receptor in the hepatopancreas and ovary of the giant mud crab, Scylla serrata by melatonin

Melatonin: Neuritogenesis and neuroprotective effects in crustacean x-organ cells

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