2020
DOI: 10.3390/ma13143190
View full text |Buy / Rent full text
|
Sign up to set email alerts
|

Abstract: Most available antiseptic solutions available today have strong antibacterial effects, however most also possess major cytotoxic effects on human gingival tissues. The VEGA Oral Care Recovery Kit (StellaLife), previously evaluated in clinical studies, consists of 16 active ingredients that are monographed in the Homeopathic Pharmacopeia of United States (HPUS) and recognized for their accelerated healing properties (reduction in post-op pain). The aim of this study was to compare VEGA to chlorhexidine (CHX) in… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

4
8
0

Year Published

2021
2021
2021
2021

Publication Types

Select...
2

Relationship

1
1

Authors

Journals

citations
Cited by 7 publications
(12 citation statements)
references
References 24 publications
(24 reference statements)
4
8
0
Order By: Relevance
“…Mariotti and Rumpf [19] postulated that CHX can reduce both collagen and non-collagen protein production and proliferation of human gingival fibroblasts (HGFs), even at very low concentrations, and this negatively affects the wound healing process. This was confirmed in a recent in vitro study in which cells were exposed to a concentration diluted 100-fold when compared to the current use in clinical practice [24].…”
Section: Introductionsupporting
confidence: 57%
“…Mariotti and Rumpf [19] postulated that CHX can reduce both collagen and non-collagen protein production and proliferation of human gingival fibroblasts (HGFs), even at very low concentrations, and this negatively affects the wound healing process. This was confirmed in a recent in vitro study in which cells were exposed to a concentration diluted 100-fold when compared to the current use in clinical practice [24].…”
Section: Introductionsupporting
confidence: 57%
“…Nonetheless, little is known about potential synergistic effects within the compound. Currently, there is only one cellular investigation of SLife, which suggested that it had superior cytocompatibility as compared to Chlorhexidine in vitro ( Fujioka-Kobayashi et al, 2020 ).…”
Section: Discussionmentioning
confidence: 99%
“…Little is known about the cytocompatibility of SLife, but the only available study has shown that cell viability of gingival fibroblasts was minimal after 5 min of stimulation with 100% SLife solution ( Fujioka-Kobayashi et al, 2020 ). To determine the maximum non-toxic (MNTD) dose of the solution we employed a concentration curve of SLife ranging from 0% (100% DMEM+) up to 60% (60% SL/40% DMEM+) v/v to challenge L929 fibroblasts for 5 min.…”
Section: Methodsmentioning
confidence: 99%
See 2 more Smart Citations