Cytophagic histiocytic panniculitis. Systemic histiocytosis presenting as chronic, nonhealing, ulcerative skin lesions

Willis, S. M.

doi:10.1001/archderm.121.7.910

Cited by 16 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…To our knowledge this patient is the youngest case re~ ported [1,3,6,7]. The search for aetiological factors, including infection-associated haemophagocytic syndrome, was negative.…”

Section: Case Reportmentioning

confidence: 82%

Histiocytic cytophagic panniculitis: Report of a case in a 12-year-old girl

et al. 1991

View full text Add to dashboard Cite

show abstract

“…To our knowledge this patient is the youngest case re~ ported [1,3,6,7]. The search for aetiological factors, including infection-associated haemophagocytic syndrome, was negative.…”

Section: Case Reportmentioning

confidence: 82%

Histiocytic cytophagic panniculitis: Report of a case in a 12-year-old girl

et al. 1991

View full text Add to dashboard Cite

show abstract

“…The multitude of clinical manifestations exhibited by these two cases in general parallel those described previously. 1s3- 4 However we wish to draw attention to the unusual manner of presentation in case 2. Although the 'patient eventually manifested the full-blown picture of CHP, presentation with ascites has hitherto not been described.…”

Section: Discussionmentioning

confidence: 97%

Cytophagic histiocytic panniculitis: A diagnostic dilemma

Cheah

Looi

Tan

et al. 1992

Hematological Oncology

View full text Add to dashboard Cite

Cytophagic histiocytic panniculitis (CHP) is a recently recognized entity that frequently poses a perplexing diagnostic problem. Although the classical case presents with a relapsing fever, subcutaneous nodules, pancytopenia and liver dysfunction, most patients have in addition a multitude of other manifestations which confuse the clinical picture. Notwithstanding the variable clinical course, the disease frequently terminates in fatal hemorrhage. Diagnosis is based on histological features. A lobular panniculitis with an infiltrate of cytologically benign cytophagocytic histiocytes in skin nodules is the sine qua non of CHP. Hence, a deep skin biopsy which includes subcutaneous fat is mandatory to establish the diagnosis. Published information regarding this newly described entity remains scarce and we report two cases of CHP, one occurring in a 30-year-old Kadazan man and another in a 17-year-old Chinese woman seen at the University Hospital, Kuala Lumpur. The latter case presented with exudative ascites, an unusual feature, possibly due to intra-abdominal panniculitis. In addition, we record the development of cirrhosis in the same patient.

show abstract

“…Спустя десятилетие после описания доброкачественного гистио-цитоза c цитофагическим Пн [5] стало ясно, что во многих случаях он демонстрирует на-личие моноклональной популяции Т-лим-фоцитов, что указывает на лимфоидное про-исхождение заболевания [7]. В последую-щем было показано, что это поражение не всегда фатально, как ранее предпологали, и может иметь благоприятное течение [7][8][9][10]. В отечественных и зарубежных рабо-тах, посвященных изучению Пн Вебе-ра-Крисчена, гистиоцитарного цитофаги-ческого Пн, диагностика осуществлялась только на клинических и гистологических проявлениях; иммуноморфологические, ви-русологические и молекулярные методы ис-следования не применялись.…”

unclassified