Cytocompatibility of Ti-6Al-4V and Ti-5Al-2.5Fe alloys according to three surface treatments, using human fibroblasts and osteoblasts

Bordji, Karim; Jouzeau, Jean‐Yves; Mainard, Didier; Payan, E.; Netter, Patrick; Rie, K.‐T.; Stucky, T.; Hage‐Ali, M.

doi:10.1016/0142-9612(96)83289-3

Cited by 175 publications

(95 citation statements)

References 29 publications

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“…Por tal motivo, es necesario recurrir a la adición de uno o más metales al elemento base, para modificar su estructura cristalina y en consecuencia sus propiedades físicas y químicas. Un ejemplo de ello es la aleación Ti-6Al-4V, a pesar de que en los últimos años se ha desencadenado una cierta controversia sobre su biocompatibilidad (Bordji, 1996;Geetha, 2009;Tapash, 2011).…”

Section: Introductionunclassified

Determinación por Visión Artificial del Factor de Degradación en Aleaciones Biocompatibles

2013

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ResumenSe determinó por visión artificial el factor de degradación de una aleación biocompatible, AISI 316LVM. Para ello, se utilizó una solución fisiológica simulada (solución de Hanks), electrolito que simula la composición presente en el organismo, es decir, el ambiente donde el implante se utilizará. El comportamiento electroquímico fue evaluado mediante curvas potencio-dinámicas. La caracterización superficial se desarrolló mediante un estereoscopio y los productos de corrosión se evaluaron mediante difracción de rayos X. El sistema usó una imagen microscópica de la superficie del material en su estado natural (brillo espejo) como parámetro base para la comparación, para definir en qué estado se encuentran las muestras una vez han pasado por las pruebas realizadas. Se encontró, que es posible estimar el factor de degradación o de deterioro en un material mediante un análisis topográfico del mismo. Palabras clave: biomateriales, degradación, visión artificial, 316LVM Computer Vision for Determination of Degradation Factor in Biocompatible Alloys AbstractThe degradation factor of a biocompatible alloy, AISI 316LVM, was determined by computer vision. For this, a simulated physiological solution (Hanks' solution) which simulates the electrolyte composition in the body, that is the environment in which the implant is used. The electrochemical behavior was evaluated by potentio-dynamic curves. The surface characterization was performed using a stereoscope and corrosion products were evaluated by X-ray diffraction. The system used a microscopic image of the surface of the material in its natural state (mirror finish) as a basis for comparison parameter to define what state are once samples have undergone testing. It was found that it is possible to estimate the factor of degradation or deterioration of a material through a topographic analysis.

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Section: Introductionunclassified

Determinación por Visión Artificial del Factor de Degradación en Aleaciones Biocompatibles

2013

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“…The addition of alloying elements to titanium (e.g., Al and V) improves titanium's mechanical properties. However, it is possible for the ions to be released and to have a toxic effect on the human organism; thus, it is important to avoid such elements [1][2][3][4][5][6]. These elements can be replaced by nontoxic elements, such as Zr, Nb, Ta, or Mo [5], although the mechanical and microstructural properties of the alloys change due to this replacement.…”

Section: Introductionmentioning

confidence: 99%

Modification of a Ti–Mo alloy surface via plasma electrolytic oxidation in a solution containing calcium and phosphorus

Simka

Krząkała

Korotin

et al. 2013

Electrochimica Acta

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a b s t r a c tInvestigations into the surface modification of a Ti-15Mo alloy via plasma electrolytic oxidation are reported. The oxidation process was conducted in a solution containing Ca(H 2 PO 2 ) 2 , H 3 PO 4 , or (HCOO) 2 Ca. Anodisation was performed at voltages in the range of 100-400 V. The morphology of the sample surface did not change during alloy oxidation at lower voltages. Higher voltages led to the incorporation of calcium and phosphorus or of calcium only into the formed oxide layer and to significant modification of the surface morphology. Based on the SEM and EDX analysis results, a set of samples was selected for further investigations. To study the surface of the Ti-Mo alloy after anodic oxidation, we used scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), thin-layer X-ray diffraction (TL-XRD), and X-ray photoelectron spectroscopy (XPS). The electrochemical characteristics of the modified alloy in Ringer's solution were determined. Anodisation results in a considerable increase in the corrosion resistance of the Ti-15Mo alloy.

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“…These are largely physical and mechanical features such as excellent fatigue and tensile strength, superior corrosion and wear resistance, low modulus of elasticity, good hardness and low density [1]. Titanium alloys are probably the most common materials used in surgical implants and devices, and in recent years has become the bio-metal of choice in dentistry.…”

Section: Introductionmentioning

confidence: 99%

On the correlation between Nd:YAG laser-induced wettability characteristics modification and osteoblast cell bioactivity on a titanium alloy

Lawrence

Hao

Chew

2006

Surface and Coatings Technology

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The factors responsible for modifications to the wettability characteristics of a titanium (Ti6Al4V) alloy bio-metal following Nd:YAG laser treatment and the effects thereof on the response of osteoblast cells were considered in this work. It was found that interaction of the Nd:YAG laser beam with the Ti6Al4V alloy resulted in the wettability characteristics of the bio-metal improving. Such improvements in the wettability characteristics of the Ti6Al4V alloy were found to be due to: an increase in the surface roughness; and increase in the surface oxygen content and an increase in the polar component of the surface energy. From the cell response tests it was determined that the osteoblast cell adhesion and proliferation on the Nd:YAG laser treated Ti6Al4V alloy samples was considerably greater than on the untreated samples. By isolating the effects of surface roughness it was possible to confirm or refute the existence of a correlation between wettability characteristics and osteoblast cell bioactivity for the Nd:YAG laser treated Ti6Al4V alloy. The findings indicated that the aspects of wettability characteristics: surface oxygen content and polar component of the surface energy play an important role in promoting cell proliferation, particularly when surface roughness was simultaneously increased. Thus it was possible to conclude that the wettability characteristics of the Nd:YAG laser treated Ti6Al4V alloy were correlated to osteoblast cell bioactivity.

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Cytocompatibility of Ti-6Al-4V and Ti-5Al-2.5Fe alloys according to three surface treatments, using human fibroblasts and osteoblasts

Cited by 175 publications

References 29 publications

Determinación por Visión Artificial del Factor de Degradación en Aleaciones Biocompatibles

Determinación por Visión Artificial del Factor de Degradación en Aleaciones Biocompatibles

Modification of a Ti–Mo alloy surface via plasma electrolytic oxidation in a solution containing calcium and phosphorus

On the correlation between Nd:YAG laser-induced wettability characteristics modification and osteoblast cell bioactivity on a titanium alloy

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