Cystic Retinal Tufts and Their Relationship to Retinal Detachment

Spectral-domain optical coherence tomography characteristics of cystic retinal tuft

“…In this study, the CRT on SD-OCT images exhibited hyperreflective irregular elevated lesions with internal hyporeflective cystoid cavities, and normal layers of the neuroepithelium could not be distinguished. Our results based on the widefield SD-OCT imaging were generally consistent with the characteristic intralesional cystic changes on histopathological analysis of CRT [2]. This demonstrates the utility of widefield SD-OCT imaging in detecting subtle features of the peripheral retinal lesions that are often hidden on standard ophthalmic examinations.…”

Spectral-domain optical coherence tomography characteristics of cystic retinal tuft

“…In this study, the CRT on SD-OCT images exhibited hyperreflective irregular elevated lesions with internal hyporeflective cystoid cavities, and normal layers of the neuroepithelium could not be distinguished. Our results based on the widefield SD-OCT imaging were generally consistent with the characteristic intralesional cystic changes on histopathological analysis of CRT [2]. This demonstrates the utility of widefield SD-OCT imaging in detecting subtle features of the peripheral retinal lesions that are often hidden on standard ophthalmic examinations.…”

Autosomal dominant peripheral cystic retinal patches and non-cystic retinal tufts associated with peripapillary crescents, retinal breaks and uveitis

“…They have features similar to cystic retinal tufts, but their size, shape and location between the posterior border of the vitreous base and equator are different from the original description of cystic retinal tufts [4,9]. This suggests that the cystic retinal patches are either variants of cystic retinal tufts or a new lesion altogether.…”

“…Cystic retinal tufts, zonular traction tufts, lattice degeneration and retinal holes associated with meridional complexes are associated with retinal detachment [3,4,5,8,9,18,25,27]. The cystic retinal patches in this kindred were different in size, morphology and location to these lesions, but their cystic appearance would suggest that they were the most probable location for the retinal breaks.…”

“…The affected members of the kindred we studied have abnormalities that we have called cystic retinal patches to indicate that they do not fit into the descriptions of well-known peripheral retinal lesions [3,4,5,8,9,18,25,27]. They have features similar to cystic retinal tufts, but their size, shape and location between the posterior border of the vitreous base and equator are different from the original description of cystic retinal tufts [4,9].…”

Navigated single-capture 3D and cross-sectional wide-field OCT of the mid and peripheral retina and vitreoretinal interface

“…Previous studies have been conducted long time ago with limitations in terms of visualization, imaging, documentation, and length of follow up. [22][23][24][25][26] This work presents the expected limitations for a pilot study being neither non-consecutive nor retrospective. However, the ability of imaging the mid and peripheral neuroretina and vitreoretinal interface using Navigated Single-Capture 3D and Cross-Sectional 23 mm long WF SS-OCT scans can be considered a landmark achievement as it can potentially change clinical management and reduce the number of patients suffering from RD and needing surgery, by allowing the early recognition of lesions that need treatment or increase the risk of RD.…”

Spectral-domain optical coherence tomography characteristics of cystic retinal tuft

“…In this study, the CRT on SD-OCT images exhibited hyperreflective irregular elevated lesions with internal hyporeflective cystoid cavities, and normal layers of the neuroepithelium could not be distinguished. Our results based on the widefield SD-OCT imaging were generally consistent with the characteristic intralesional cystic changes on histopathological analysis of CRT [2]. This demonstrates the utility of widefield SD-OCT imaging in detecting subtle features of the peripheral retinal lesions that are often hidden on standard ophthalmic examinations.…”

Autosomal dominant peripheral cystic retinal patches and non-cystic retinal tufts associated with peripapillary crescents, retinal breaks and uveitis

“…They have features similar to cystic retinal tufts, but their size, shape and location between the posterior border of the vitreous base and equator are different from the original description of cystic retinal tufts [4,9]. This suggests that the cystic retinal patches are either variants of cystic retinal tufts or a new lesion altogether.…”

“…Cystic retinal tufts, zonular traction tufts, lattice degeneration and retinal holes associated with meridional complexes are associated with retinal detachment [3,4,5,8,9,18,25,27]. The cystic retinal patches in this kindred were different in size, morphology and location to these lesions, but their cystic appearance would suggest that they were the most probable location for the retinal breaks.…”

“…The affected members of the kindred we studied have abnormalities that we have called cystic retinal patches to indicate that they do not fit into the descriptions of well-known peripheral retinal lesions [3,4,5,8,9,18,25,27]. They have features similar to cystic retinal tufts, but their size, shape and location between the posterior border of the vitreous base and equator are different from the original description of cystic retinal tufts [4,9].…”

Navigated single-capture 3D and cross-sectional wide-field OCT of the mid and peripheral retina and vitreoretinal interface

“…Previous studies have been conducted long time ago with limitations in terms of visualization, imaging, documentation, and length of follow up. [22][23][24][25][26] This work presents the expected limitations for a pilot study being neither non-consecutive nor retrospective. However, the ability of imaging the mid and peripheral neuroretina and vitreoretinal interface using Navigated Single-Capture 3D and Cross-Sectional 23 mm long WF SS-OCT scans can be considered a landmark achievement as it can potentially change clinical management and reduce the number of patients suffering from RD and needing surgery, by allowing the early recognition of lesions that need treatment or increase the risk of RD.…”

Spectral-domain optical coherence tomography characteristics of cystic retinal tuft

“…In this study, the CRT on SD-OCT images exhibited hyperreflective irregular elevated lesions with internal hyporeflective cystoid cavities, and normal layers of the neuroepithelium could not be distinguished. Our results based on the widefield SD-OCT imaging were generally consistent with the characteristic intralesional cystic changes on histopathological analysis of CRT [2]. This demonstrates the utility of widefield SD-OCT imaging in detecting subtle features of the peripheral retinal lesions that are often hidden on standard ophthalmic examinations.…”

Autosomal dominant peripheral cystic retinal patches and non-cystic retinal tufts associated with peripapillary crescents, retinal breaks and uveitis

“…They have features similar to cystic retinal tufts, but their size, shape and location between the posterior border of the vitreous base and equator are different from the original description of cystic retinal tufts [4,9]. This suggests that the cystic retinal patches are either variants of cystic retinal tufts or a new lesion altogether.…”

“…Cystic retinal tufts, zonular traction tufts, lattice degeneration and retinal holes associated with meridional complexes are associated with retinal detachment [3,4,5,8,9,18,25,27]. The cystic retinal patches in this kindred were different in size, morphology and location to these lesions, but their cystic appearance would suggest that they were the most probable location for the retinal breaks.…”

“…The affected members of the kindred we studied have abnormalities that we have called cystic retinal patches to indicate that they do not fit into the descriptions of well-known peripheral retinal lesions [3,4,5,8,9,18,25,27]. They have features similar to cystic retinal tufts, but their size, shape and location between the posterior border of the vitreous base and equator are different from the original description of cystic retinal tufts [4,9].…”

Navigated single-capture 3D and cross-sectional wide-field OCT of the mid and peripheral retina and vitreoretinal interface

“…Previous studies have been conducted long time ago with limitations in terms of visualization, imaging, documentation, and length of follow up. [22][23][24][25][26] This work presents the expected limitations for a pilot study being neither non-consecutive nor retrospective. However, the ability of imaging the mid and peripheral neuroretina and vitreoretinal interface using Navigated Single-Capture 3D and Cross-Sectional 23 mm long WF SS-OCT scans can be considered a landmark achievement as it can potentially change clinical management and reduce the number of patients suffering from RD and needing surgery, by allowing the early recognition of lesions that need treatment or increase the risk of RD.…”