1989
DOI: 10.1001/archderm.125.4.507
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Cyclosporine in the treatment of psoriatic arthritis

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Cited by 25 publications
(15 citation statements)
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“…(1) Efficacy in arthritis: The efficacy of cyclosporin monotherapy has been reported. [248][249][250][251][252] Prospective open-label clinical studies of 3-5 mg/kg per day cyclosporin and methotrexate showed that joint symptoms were slightly improved by both drugs. [252][253][254] In a study evaluating the alleviation of arthritic pain as an end-point, 3 mg/kg per day of cyclosporin was more effective than sulfasalazine.…”
Section: Degree Of Recommendation: B-c1mentioning
confidence: 99%
“…(1) Efficacy in arthritis: The efficacy of cyclosporin monotherapy has been reported. [248][249][250][251][252] Prospective open-label clinical studies of 3-5 mg/kg per day cyclosporin and methotrexate showed that joint symptoms were slightly improved by both drugs. [252][253][254] In a study evaluating the alleviation of arthritic pain as an end-point, 3 mg/kg per day of cyclosporin was more effective than sulfasalazine.…”
Section: Degree Of Recommendation: B-c1mentioning
confidence: 99%
“…However, 2 weeks after discontinuation of cyclosporine, joint pain and swelling recurred. 50 In an open-label prospective study, all seven patients with psoriatic arthritis had improvement of joint pain and swelling after cyclosporine 3.5 mg/kg/day for 6 months. The time to relapse was not documented in this study.…”
Section: Psoriatic Arthritismentioning
confidence: 96%
“…The drug has also been reported to be effective in erythrodermic psoriasis, [27][28][29][30] generalized pustular psoriasis, [31][32][33][34] palmoplantar pustulosis, 35,36 acrodermatitis continua of Hallopeau, [37][38][39] psoriatic nail dystrophy [40][41][42][43] and psoriatic arthropathy. [44][45][46][47] For psoriasis vulgaris, the 'standard' regimen comprises an initial dose for inducing remission of 2Á5-5 mg kg À1 per day given orally, in a single dose or two divided doses. The higher initial dosage of 5 mg kg À1 per day can be given when rapid control is required.…”
Section: Severe Psoriasismentioning
confidence: 99%