DOI: 10.1590/s0036-46651989000600009
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Abstract: SUMMARYCoccidioidomycosis i s a systemic mycosis, endemic i n ari d area s of th e America n continent.The ra t wa s employe d a s a n experimenta l host , sinc e i t ha d bee n show n t o reproduce huma n lesion s an d presen t a chroni c cours e o f diseas e with granuloma s mainly restricte d t o lungs . there wa s greate r funga l sprea d tha n i n control s receivin g C . immitis alone , whic h proved self-limitin g i n th e latter . I n contrast , schedul e C le d t o 559 r mortality , wit h both humora … Show more

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