Cyclopentolate Associated With Two Cases of Grand Mal Seizure

Cycloplegic Refraction in Children with Cyclopentolate versus Atropine

“…However, central nervous system toxicity including mental deterioration and grand mal seizure can occur with cyclopentolate [37,38]. No adverse effects were recorded and this may be explained by small sample size used.…”

Cycloplegic Refraction in Children with Cyclopentolate versus Atropine

“…However, central nervous system toxicity including mental deterioration and grand mal seizure can occur with cyclopentolate [37,38]. No adverse effects were recorded and this may be explained by small sample size used.…”

Cycloplegic Refraction in Hyperopic Children: Effectiveness of a 0.5% Tropicamide and 0.5% Phenylephrine Addition to 1% Cyclopentolate Regimen

“…In children, these short-acting agents are preferred for cycloplegic refraction. However, the stinging sensation of cyclopentolate and possible side effects of central nervous system toxicity with visual and tactile hallucinations, cerebellar dysfunction, drowsiness, and grand mal seizures (among others) causes concern among physicians prescribing the drug to children for cycloplegic refraction [222324]. During our study period, no significant side effects of cyclopentolate, including central nervous system toxicity, were observed.…”

Machine‐learning random forest algorithms predict post‐cycloplegic myopic corrections from noncycloplegic clinical data

“…36,37 Additionally, the use of these agents may lead to systemic symptoms such as skin flushing, dry mouth, fever, or ocular irritation, with potential risk factors for central nervous system or cardiovascular diseases. [38][39][40] These factors may cause patients, especially children or their parents, to reject the use of cycloplegic agents. For those declining cycloplegia, our model has somewhat addressed the challenge of underestimating patients' objective refraction due to the refusal to use cycloplegic agents.…”

Cycloplegic Refraction in Children with Cyclopentolate versus Atropine

“…However, central nervous system toxicity including mental deterioration and grand mal seizure can occur with cyclopentolate [37,38]. No adverse effects were recorded and this may be explained by small sample size used.…”

Cycloplegic Refraction in Hyperopic Children: Effectiveness of a 0.5% Tropicamide and 0.5% Phenylephrine Addition to 1% Cyclopentolate Regimen

“…In children, these short-acting agents are preferred for cycloplegic refraction. However, the stinging sensation of cyclopentolate and possible side effects of central nervous system toxicity with visual and tactile hallucinations, cerebellar dysfunction, drowsiness, and grand mal seizures (among others) causes concern among physicians prescribing the drug to children for cycloplegic refraction [222324]. During our study period, no significant side effects of cyclopentolate, including central nervous system toxicity, were observed.…”

Machine‐learning random forest algorithms predict post‐cycloplegic myopic corrections from noncycloplegic clinical data

“…36,37 Additionally, the use of these agents may lead to systemic symptoms such as skin flushing, dry mouth, fever, or ocular irritation, with potential risk factors for central nervous system or cardiovascular diseases. [38][39][40] These factors may cause patients, especially children or their parents, to reject the use of cycloplegic agents. For those declining cycloplegia, our model has somewhat addressed the challenge of underestimating patients' objective refraction due to the refusal to use cycloplegic agents.…”

Cycloplegic Refraction in Children with Cyclopentolate versus Atropine

“…However, central nervous system toxicity including mental deterioration and grand mal seizure can occur with cyclopentolate [37,38]. No adverse effects were recorded and this may be explained by small sample size used.…”

Cycloplegic Refraction in Hyperopic Children: Effectiveness of a 0.5% Tropicamide and 0.5% Phenylephrine Addition to 1% Cyclopentolate Regimen

“…In children, these short-acting agents are preferred for cycloplegic refraction. However, the stinging sensation of cyclopentolate and possible side effects of central nervous system toxicity with visual and tactile hallucinations, cerebellar dysfunction, drowsiness, and grand mal seizures (among others) causes concern among physicians prescribing the drug to children for cycloplegic refraction [222324]. During our study period, no significant side effects of cyclopentolate, including central nervous system toxicity, were observed.…”

Machine‐learning random forest algorithms predict post‐cycloplegic myopic corrections from noncycloplegic clinical data

“…36,37 Additionally, the use of these agents may lead to systemic symptoms such as skin flushing, dry mouth, fever, or ocular irritation, with potential risk factors for central nervous system or cardiovascular diseases. [38][39][40] These factors may cause patients, especially children or their parents, to reject the use of cycloplegic agents. For those declining cycloplegia, our model has somewhat addressed the challenge of underestimating patients' objective refraction due to the refusal to use cycloplegic agents.…”