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Cited by 105 publications
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References 30 publications
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“…Du et al (13) showed that cyclically strained HUVEC and HAEC (10% deformation average, 1 Hz) both induced AP-1 and NF-B in a monophasic manner, consistent with our findings that 10% cyclic strain upregulated VCAM-1 in both cell types. Interestingly, as noted by Dagia et al (9), redox-sensitive GATA is involved in VCAM-1 expression in tumor necrosis factor (TNF)-␣-stimulated HUVEC (41) but not TNF-␣-stimulated HAEC.…”
Section: Discussionsupporting
confidence: 93%
“…Du et al (13) showed that cyclically strained HUVEC and HAEC (10% deformation average, 1 Hz) both induced AP-1 and NF-B in a monophasic manner, consistent with our findings that 10% cyclic strain upregulated VCAM-1 in both cell types. Interestingly, as noted by Dagia et al (9), redox-sensitive GATA is involved in VCAM-1 expression in tumor necrosis factor (TNF)-␣-stimulated HUVEC (41) but not TNF-␣-stimulated HAEC.…”
Section: Discussionsupporting
confidence: 93%
“…41 Nonetheless, cyclic strain-mediated signaling pathways have been directly linked to specific trans-acting factors, such as nuclear factor-B and activator protein-2. 42,43 As noted, both factors have corresponding cis-acting elements in the syndecan-4 promoter region.…”
Section: Discussionmentioning
confidence: 87%
“…Mechanical force is classified into shear stress, compressive stress and stretch stress, and are thought to play roles as tissue-specific regulators of extracellular matrix (ECM) homeostasis. For example, bloodstream affects several vascular components as fluid shear stress, whereas blood pressure will act as stretch stress (Du et al, 1995). Also, in the bone, differentiation, growth and several phenotype expression in the osteoblasts were regulated by several mechanical forces (Singh et al, 2007).…”
Section: Introductionmentioning
confidence: 99%