Ullmann's Encyclopedia of Industrial Chemistry 2000
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Cyanuric Acid and Cyanuric Chloride
Abstract: The article contains sections titled: 1. Introduction 2. Cyanuric Acid … Show more
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Cited by 61 publications
(22 citation statements)
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Abstract
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“…Treatment of cyanuric acid (103) with ammonia under the influence of pressure and 350–400 °C afforded melamine 69. 87 Melamine is a durable thermosetting plastic utilized in high-pressure decorative laminates, 88 insulation, 89 and fire-retardant additives, 90 as well as in the impregnation of décor paper, 91 and fertilizer for crops. 92 Also, melamine derivatives treat African trypanosomiasis.…”
Section: Synthesis
mentioning
confidence: 99%
“…Conversely, replacing three hydrogens of cyanuric acid (103) when it is in the form of enol with an alkali earth metal such as NaOH furnished triazine salts 69 ( Scheme 41 ). 87 The harsh thermal conditions in method A may promote efficient substitution; however, decomposition may occur, leading to decreasing selectivity. In contrast, the lower temperature in method B allow better control and enhance the selectivity.…”
Section: Synthesis
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Treatment of cyanuric acid (103) with ammonia under the influence of pressure and 350–400 °C afforded melamine 69. 87 Melamine is a durable thermosetting plastic utilized in high-pressure decorative laminates, 88 insulation, 89 and fire-retardant additives, 90 as well as in the impregnation of décor paper, 91 and fertilizer for crops. 92 Also, melamine derivatives treat African trypanosomiasis.…”
Section: Synthesis
mentioning
confidence: 99%
“…Conversely, replacing three hydrogens of cyanuric acid (103) when it is in the form of enol with an alkali earth metal such as NaOH furnished triazine salts 69 ( Scheme 41 ). 87 The harsh thermal conditions in method A may promote efficient substitution; however, decomposition may occur, leading to decreasing selectivity. In contrast, the lower temperature in method B allow better control and enhance the selectivity.…”
Section: Synthesis
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…NHDT is unstable and gradually hydrolyzes during storage. [38][39][40][41][42] Its solution changes from alkaline to acidic and a large amount of white precipitate appears at last in a non-alkaline solution. HNMR spectra analysis showed that the white precipitate is cyanuric acid (5).…”
Section: Analysis Of Nhdt and Its Hydrolyzed Products
mentioning
confidence: 99%
“…The hydrolysis process of the NHDT under alkaline conditions is verified by the test method discussed later and by existing studies. [38][39][40][41][42] Therefore, the hydrolyzed products of NHDT are compound 4, compound 6 and Cl − under alkaline conditions.…”
Section: Analysis Of Nhdt and Its Hydrolyzed Products
mentioning
confidence: 99%
Abstract
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“…Compound ( 40) is a bioconjugate incorporating the structural component of s-triazine tethered with tetrazole. 47 In vitro, analysis of (40) suggested that exhibited good cytotoxicity against human alveolar basal epithelium adenocarcinoma A549 (IC 50 = 41.3 mmol L −1 ), human ovarian teratocarcinoma PA-1 (IC 50 = 10.6 mmol L −1 ), hepatocarcinoma Huh7 (IC 50 = 19.9 mmol L −1 ), cervical cancer HeLa (IC 50 = 3.7 mmol L −1 ), and human embryonic kidney HEK293 (IC 50 = 15.8 mmol L −1 ). Aer investigation, it was suggested that the possible mechanism of cytotoxicity is through HIF pathway inhibition.…”
Section: Anticancer Activity
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Treatment of cyanuric acid (103) with ammonia under the influence of pressure and 350–400 °C afforded melamine 69. 87 Melamine is a durable thermosetting plastic utilized in high-pressure decorative laminates, 88 insulation, 89 and fire-retardant additives, 90 as well as in the impregnation of décor paper, 91 and fertilizer for crops. 92 Also, melamine derivatives treat African trypanosomiasis.…”
Section: Synthesis
mentioning
confidence: 99%
“…Conversely, replacing three hydrogens of cyanuric acid (103) when it is in the form of enol with an alkali earth metal such as NaOH furnished triazine salts 69 ( Scheme 41 ). 87 The harsh thermal conditions in method A may promote efficient substitution; however, decomposition may occur, leading to decreasing selectivity. In contrast, the lower temperature in method B allow better control and enhance the selectivity.…”
Section: Synthesis
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…NHDT is unstable and gradually hydrolyzes during storage. [38][39][40][41][42] Its solution changes from alkaline to acidic and a large amount of white precipitate appears at last in a non-alkaline solution. HNMR spectra analysis showed that the white precipitate is cyanuric acid (5).…”
Section: Analysis Of Nhdt and Its Hydrolyzed Products
mentioning
confidence: 99%
“…The hydrolysis process of the NHDT under alkaline conditions is verified by the test method discussed later and by existing studies. [38][39][40][41][42] Therefore, the hydrolyzed products of NHDT are compound 4, compound 6 and Cl − under alkaline conditions.…”
Section: Analysis Of Nhdt and Its Hydrolyzed Products
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Compound ( 40) is a bioconjugate incorporating the structural component of s-triazine tethered with tetrazole. 47 In vitro, analysis of (40) suggested that exhibited good cytotoxicity against human alveolar basal epithelium adenocarcinoma A549 (IC 50 = 41.3 mmol L −1 ), human ovarian teratocarcinoma PA-1 (IC 50 = 10.6 mmol L −1 ), hepatocarcinoma Huh7 (IC 50 = 19.9 mmol L −1 ), cervical cancer HeLa (IC 50 = 3.7 mmol L −1 ), and human embryonic kidney HEK293 (IC 50 = 15.8 mmol L −1 ). Aer investigation, it was suggested that the possible mechanism of cytotoxicity is through HIF pathway inhibition.…”
Section: Anticancer Activity
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Treatment of cyanuric acid (103) with ammonia under the influence of pressure and 350–400 °C afforded melamine 69. 87 Melamine is a durable thermosetting plastic utilized in high-pressure decorative laminates, 88 insulation, 89 and fire-retardant additives, 90 as well as in the impregnation of décor paper, 91 and fertilizer for crops. 92 Also, melamine derivatives treat African trypanosomiasis.…”
Section: Synthesis
mentioning
confidence: 99%
“…Conversely, replacing three hydrogens of cyanuric acid (103) when it is in the form of enol with an alkali earth metal such as NaOH furnished triazine salts 69 ( Scheme 41 ). 87 The harsh thermal conditions in method A may promote efficient substitution; however, decomposition may occur, leading to decreasing selectivity. In contrast, the lower temperature in method B allow better control and enhance the selectivity.…”
Section: Synthesis
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…NHDT is unstable and gradually hydrolyzes during storage. [38][39][40][41][42] Its solution changes from alkaline to acidic and a large amount of white precipitate appears at last in a non-alkaline solution. HNMR spectra analysis showed that the white precipitate is cyanuric acid (5).…”
Section: Analysis Of Nhdt and Its Hydrolyzed Products
mentioning
confidence: 99%
“…The hydrolysis process of the NHDT under alkaline conditions is verified by the test method discussed later and by existing studies. [38][39][40][41][42] Therefore, the hydrolyzed products of NHDT are compound 4, compound 6 and Cl − under alkaline conditions.…”
Section: Analysis Of Nhdt and Its Hydrolyzed Products
mentioning
confidence: 99%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Compound ( 40) is a bioconjugate incorporating the structural component of s-triazine tethered with tetrazole. 47 In vitro, analysis of (40) suggested that exhibited good cytotoxicity against human alveolar basal epithelium adenocarcinoma A549 (IC 50 = 41.3 mmol L −1 ), human ovarian teratocarcinoma PA-1 (IC 50 = 10.6 mmol L −1 ), hepatocarcinoma Huh7 (IC 50 = 19.9 mmol L −1 ), cervical cancer HeLa (IC 50 = 3.7 mmol L −1 ), and human embryonic kidney HEK293 (IC 50 = 15.8 mmol L −1 ). Aer investigation, it was suggested that the possible mechanism of cytotoxicity is through HIF pathway inhibition.…”
Section: Anticancer Activity
mentioning
confidence: 99%